Aaron Carroll

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Review: Treatment of 5 critically ill patients with COVID-19 with convalescent plasma

In this preliminary uncontrolled case series of 5 critically ill patients with COVID-19 and ARDS, convalescent plasma containing neutralizing antibody showed promising results in treating severe cases. These observations require evaluation in clinical trials. We would really like to haveRead More
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Review: Public health responses to COVID-19 outbreaks on cruise ships — Worldwide, February–March 2020

This report details why cruises are at significant risk for outbreaks, and no one should be going on one during the COVID-19 pandemic. About 30 million people travel on 272 cruise ships each year worldwide. Cruise ships are a closedRead More
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Review: Epidemiology of COVID-19 in a long-term care facility in King County, Washington

This study explains why long-term care facilities are at high risk for Covid-19 outbreaks and must identify and exclude potentially infected staff and visitors, actively monitor for potentially infected patients, and implement appropriate infection prevention and control measures. On FebruaryRead More
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Review: Clinical characteristics of 113 deceased patients with coronavirus disease 2019: Retrospective study

This study comparing patients who died from COVID to those who recovered details some laboratory values that are more/less common as well as the most common complications. This study compared the clinical characteristics of 113 patients who died from COVIDRead More
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Review: Epidemiological characteristics of 2143 pediatric patients with 2019 coronavirus disease in China

This study concluded that children of all ages are susceptible to COVID-19, with no significant gender differences. Young children, particularly infants, are more vulnerable to infection. Objective: To identify the epidemiological characteristics and transmission patterns of children infected with COVID-19Read More
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Review: Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (SARS-CoV2)

This modeling study argues that undocumented cases are very common and lead to most of the spread of SARS-CoV2. One of the biggest concerns of public health officials is that people can be infected with SARS-CoV2, not know it, andRead More
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Review: Case-fatality rate and characteristics of patients dying in relation to COVID-19 in Italy

At the outset of Italy’s COVID-19 outbreak, they launched a surveillance system to collect information on all people with COVID-19 in-country. There are concerns as to why the fatality rate (what percent of people who are infected die) is soRead More
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Review: Profiling early humoral response to diagnose novel coronavirus disease (COVID-19)

This study provides key data on how long it takes to develop antibodies after symptoms of COVID (5 days for IgM and IgA, and 14 days for IgG) and argues that combining IgM ELISA assay with PCR makes a falseRead More
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