Megan McHenry

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About Megan McHenry

Megan S. McHenry, MD, MS, FAAP is a pediatrician and an Assistant Professor of Pediatrics in the Ryan White Center for Pediatric Infectious Disease and Global Health at Indiana University School of Medicine. Dr. McHenry's research focuses on early childhood development in children living in resource-limited settings. This work is frequently aligned with community-engaged research and dissemination and implementation science frameworks. She primarily conducts research in collaboration with the Academic Model for Providing Access to Healthcare (AMPATH) Research Network in Kenya. Dr. McHenry currently has a career development award through the National Institutes of Health to develop a neurodevelopmental screening program for children born to HIV-infected mothers in Kenya.

Dr. McHenry is also the Director of Pediatric Global Health Education and a co-Director of the Morris Green Physician-Scientist Development Program at Indiana University School of Medicine. In additional to global health lectures, she also educates residents and students on early childhood development, basic biostatistical techniques, research methodologies, and research ethics. She mentors multiple pediatric fellows, residents, and medical students interested in early childhood development within global contexts.

Clinical Characteristics: Within this surveillance cohort of 598 hospitalized pregnant women with COVID-19, 55% were asymptomatic at admission. Among these pregnant women, 2% had pregnancy losses during COVID-19-associated hospitalizations and were experienced by both symptomatic and asymptomatic women. Inflammation: Within Read More
Clinical characteristics This cross-sectional study examined racial/ethnic variation in nasal gene expression of trans-membrane serine protease 2 (TMPRSS2). Within the 305 individuals with tissue samples (nasal epithelium collected during 2015-2018),  TMPRSS2 expression was significantly higher in Black individuals compared with Read More
Clinical Characteristics In this case series of 91 children who tested positive for COVID-19 in Korea, 22% were asymptomatic. These children were tested for COVID-19 when they had a history of close contact with confirmed cases. Only 8.5% of symptomatic Read More
Clinical Characteristics This prospective observational cohort study describes the clinical characteristics of 651 children and adolescents from England, Wales, and Scotland, of which 52 met WHO criteria for MIS-C. In addition to the WHO diagnostic criteria, children with MIS-C were Read More
Transmission A small study of 18 breastfeeding women with COVID-19 found that SARS-CoV-2 RNA was found in only one sample, and a viral culture from that sample was negative. This suggests that breast milk is an unlikely source of infection Read More
Personal Protective Equipment A quality improvement study looking at comparative fitted filtration efficiencies for various mask styles found N95 makes had efficiencies of 98.%; surgical mask with ties was 71.5%; procedure mask with ear loops was 38.1%. Used and/or expired Read More
Case reports: A case report of early-onset, severe COVID-19 infection in a neonate was published, suggestive of vertical transmission. Another case report describes an infant who present with incomplete Kawaski Disease as their primary symptoms of COVID-19 infection. Treatment: Within Read More
Clinical Testing and Evaluations In a cohort of 145 patients with mild to moderate COVID-19 illness, replication of SARS-CoV-2 in older children led to similar levels of viral RNA as adults, but significantly greater amounts are detected in children younger Read More
Vaccine Update:  The mRNA-1273 vaccine (from Moderna and NIAID) induced anti-SARS-COV-2 immune responses (anti-Spike-2P glycoprotein antibody) in all participants and no trial-limiting safety concerns were identified. Epidemiology: During hospital-wide SARS-CoV-2 antibody (Ab) screening in healthcare workers (HCW) and staff in Read More
This cross-sectional study found that the prevalence of SARS-CoV-2 in the asymptomatic adult population of the Indianapolis metropolitan area was 3.1% Study called asymptomatic novel CORonavirus iNfection (ACORN), led by Eli Lilly researchers between April 7, 2020 and May 16, Read More

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