Megan McHenry

About Megan McHenry

Megan S. McHenry, MD, MS, FAAP is a pediatrician and an Assistant Professor of Pediatrics in the Ryan White Center for Pediatric Infectious Disease and Global Health at Indiana University School of Medicine. Dr. McHenry's research focuses on early childhood development in children living in resource-limited settings. This work is frequently aligned with community-engaged research and dissemination and implementation science frameworks. She primarily conducts research in collaboration with the Academic Model for Providing Access to Healthcare (AMPATH) Research Network in Kenya. Dr. McHenry currently has a career development award through the National Institutes of Health to develop a neurodevelopmental screening program for children born to HIV-infected mothers in Kenya.

Dr. McHenry is also the Director of Pediatric Global Health Education and a co-Director of the Morris Green Physician-Scientist Development Program at Indiana University School of Medicine. In additional to global health lectures, she also educates residents and students on early childhood development, basic biostatistical techniques, research methodologies, and research ethics. She mentors multiple pediatric fellows, residents, and medical students interested in early childhood development within global contexts.

Review: A cross‐sectional community‐based observational study of asymptomatic SARS‐CoV‐2 prevalence in the greater Indianapolis area

This cross-sectional study found that the prevalence of SARS-CoV-2 in the asymptomatic adult population of the Indianapolis metropolitan area was 3.1% Study called asymptomatic novel CORonavirus iNfection (ACORN), led by Eli Lilly researchers between April 7, 2020 and May 16,Read More
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Review: Temperature, humidity, and latitude analysis to estimate potential spread and seasonality of coronavirus disease 2019 (COVID-19)

The cohort study modeled data from 50 different cities and found that SARS-CoV-2 appears to behave like a seasonal respiratory virus.  8 cities w/ substantial spread of COVID-19 were compared with 42 cities that have not been affected or didRead More
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Review: Cardiac MRI of children with multisystem inflammatory syndrome (MIS-C) associated with COVID-19: cCase series

This case series reviewed the cardiac MRIs of 4 children and adolescents with multisystem inflammatory syndrome in children (MIS-C), with findings favoring post-infectious myocarditis without signs of coronary abnormalities.  Study took place in France All 4 children underwent transthoracic echocardiographyRead More
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Review: Retraction notice: Cardiovascular disease, drug therapy, and mortality in COVID-19

A retraction notice was published regarding the study titled: “Cardiovascular disease, drug therapy, and mortality in COVID-19,” which appeared in The New England Journal of Medicine on May 1st.  Because of concerns that arose from a separate study concerning dataRead More
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Review: Retraction notice: Hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19: a multinational registry analysis

A retraction notice was published regarding the study titled: “Hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19: a multinational registry analysis,” which appeared in The Lancet on May 22nd.  Concerns about the data were raised andRead More
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Review: A randomized trial of hydroxychloroquine as postexposure prophylaxis for COVID-19

This randomized trial showed that hydroxychloroquine did not prevent presumed/confirmed COVID-19 when used as post-exposure prophylaxis within 4 days of high- or moderate-risk COVID-19 exposure. This randomized, double-blind, placebo-controlled trial occurred across the United States and parts of Canada EnrolledRead More
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Review: Effect of convalescent plasma therapy on time to clinical improvement in patients with severe and life-threatening COVID-19: A randomized clinical trial

This randomized clinical trial showed that convalescent plasma therapy + standard treatment did not improve time to clinic improvement within 28 days compared to standard treatment alone in patients with severe or life-threatening COVID-19.  Patients were recruited from 7 medicalRead More
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Review: Impact of COVID-19 pandemic on ST‐elevation myocardial infarction in a non‐COVID-19 epicenter

This study found that during the COVID-19 pandemic, patients presenting for ST-elevation myocardial infarction (STEMI) were more likely to present late and have lower left ventricle ejection fraction (LVEF) on presentation.   From January 1, 2020, to April 15, 2020, 143Read More
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Review: Effects of non-pharmaceutical interventions on COVID-19 cases, deaths, and demand for hospital services in the UK: a modelling study

This modeling study explored different interventions (not involving medications/vaccines) influencing new cases and deaths related to COVID-19 and found that intermittent periods of more intensive lockdown-type measures may be necessary to prevent healthcare systems from being overwhelmed.  The model exploredRead More
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Review: Delayed specific IgM antibody responses observed among COVID-19 patients with severe progression

This observational study found that half of the patient with negative IgM and RT-qPCR-positive SARS-CoV-2 had severe COVID-19 disease.  IgM-based gold immunochromatographic assay (GICA) is the test used within this study, to investigate its utility Severe cases were defined asRead More
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