COVID-19: Expert Review of Relevant and Emerging Literature

COVID-19: Expert Reviews of Relevant and Emerging Literature2020-08-17T11:22:55-04:00

This study investigated the case fatality rate (CFR) among confirmed COVID-19 cases (N=22,512) in Italy, using Italian National Institute of Health surveillance data up to March 17, 2020.

In this small sample of COVID-19 infected patients who were mostly young, male with mild infections, half were viral positive even after resolution of their symptoms. This information can provide useful tool for clinicians and policymakers to ensure that recovered patients do not spread the virus.

This document presents estimates of predicted health service utilization and deaths due to COVID-19 by day for the next 4 months for each state in the US.

This study provides useful information about when we can expect antibodies to appear after infection, and how that might be used in future clinical testing.

We are still learning about the antibody response in patients infected with COVID-19 This is a case series of 173 patients with SARS-CoV-2. Serial plasma samples (n=535) were collected during the hospitalizations, and they tested for total antibodies (Ab), IgM and IgG.

In an editorial, UK’s government was criticized for being slow to respond to the pandemic by not following instructive experiences from other countries.

In this preliminary uncontrolled case series of 5 critically ill patients with COVID-19 and ARDS, convalescent plasma containing neutralizing antibody showed promising results in treating severe cases. These observations require evaluation in clinical trials.

We would really like to have a treatment for COVID-19. This preliminary study sought to determine whether a plasma transfusion from recovered patients may help critically ill patients with severe infections.

The authors describe a case series of 5 critically ill patients with laboratory-confirmed COVID-19 and acute respiratory distress syndrome (ARDS) who had:

This report details why cruises are at significant risk for outbreaks, and no one should be going on one during the COVID-19 pandemic.

About 30 million people travel on 272 cruise ships each year worldwide. Cruise ships are a closed environment where travelers from many countries come into contact with each other. Because of that, they are often the setting for outbreaks. This report details more than 800 cases of lab-confirmed cased of COVID-19 from three cruise ship voyages. Other cruises have detailed smaller outbreaks. Ten associated deaths have been reported so far.

This study explains why long-term care facilities are at high risk for Covid-19 outbreaks and must identify and exclude potentially infected staff and visitors, actively monitor for potentially infected patients, and implement appropriate infection prevention and control measures.

On February 28, 2020, after a confirmed case of Covid-19 was identified, the authors launched a case investigation, contact tracing, quarantine of exposed persons, isolation of confirmed and suspected cases, and on-site enhancement of infection prevention and control. This report details their findings.

This study comparing patients who died from COVID to those who recovered details some laboratory values that are more/less common as well as the most common complications.

This study compared the clinical characteristics of 113 patients who died from COVID to 161 who recovered in China. Key findings included:

Local law enforcement in Florida and Illinois have arrested individuals for endangering others during the outbreak.

This study investigated the case fatality rate (CFR) among confirmed COVID-19 cases (N=22,512) in Italy, using Italian National Institute of Health surveillance data up to March 17, 2020.

In this randomized control trial, health care providers were less likely to accurately recall information when overloaded with too much and too frequent communication during an emergency.

In this paper series on risk communication in times of an epidemic or pandemic, an international interdisciplinary team determined that transparent communication can build credibility and trust during a pandemic.

This study concluded that children of all ages are susceptible to COVID-19, with no significant gender differences. Young children, particularly infants, are more vulnerable to infection.

Objective: To identify the epidemiological characteristics and transmission patterns of children infected with COVID-19

Data: Nationwide case series of 2143 children with COVID-19 in China from January 16 to February 8, 2020

Results: There were 731 (34.1%) laboratory-confirmed cases and 1412 (65.9%) suspected cases.

This modeling study argues that undocumented cases are very common and lead to most of the spread of SARS-CoV2.

One of the biggest concerns of public health officials is that people can be infected with SARS-CoV2, not know it, and infect others. We don’t know how many such people exist, and how contagious they are.

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