Chemical Genomics Core Facility seminar: Structure-activity relationships by nuclear magnet resonance (NMR)

December 18, 2020 @ 4:00 pm – 5:00 pm America/Indiana/Indianapolis Timezone

The IU School of Medicine Chemical Genomics Core Facility (CGCF) is planning web-based tutorials and seminar presentations about some of their new services.

The third event will be on Friday, December 18 at 4 pm. It will be about structure-activity relationships by nuclear magnet resonance (NMR) by Ratan Rai, PhD.

NMR is a powerful technique to detect and characterize 3D structures and dynamics of biomacromolecules and their interactions. It has emerged as an excellent tool for the identification of small organic molecules that weakly bind to a target macromolecule and will then be modified or added to another small molecule to act as a potent inhibitor. In this seminar, Rai will explain NMR as a tool for fragment-based drug discovery and how to utilize this approach to identify and validate initial hits and generate leads. The core facility is equipped with a 600 MHz solution NMR with cryo-probe for the structure elucidation of biomolecules and interaction study.

Join from computer or mobile:
Meeting ID: 875 8750 0060
Password: 043971

|2020-10-12T20:39:25-04:00October 12th, 2020|0 Comments

About the Author:

Anna Carrera
Anna Carrera is the research communications manager for Indiana University's Precision Health Initiative, IU School of Medicine Research Affairs and the Indiana Clinical and Translational Sciences Institute. She joined the team in June 2019 after working as a TV news reporter for ten years. She loves sharing stories about the great research being done across the state to improve the health of Hoosiers.

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