The All of Us Research Program includes data that is powering more than 6,500 active research projects and offers researchers a variety of tools for analysis.
The Indiana Clinical and Translational Sciences Institute (CTSI) is taking part in an ambitious nationwide effort to accelerate research aimed at improving the health of our nation. The Indiana CTSI initiative supports the goal of the National Institutes of Health’s (NIH) All of Us Research Program to advance disease prevention and treatment by considering individual variability in genetic makeup, lifestyle, and environment. For this purpose, All of Us is establishing one of the largest and most diverse biomedical, social, and environmental data resources available for research. All of Us aims to enroll at least one million participants who reflect the diversity of the country to advance precision medicine research and fuel new insights into human health.
As a member of a national consortium of the Clinical and Translational Science Awards (CTSA) Community Engagement Cores led by Dr. Linda Cottler from the University of Florida and Dr. Mickey Eder from the University of Minnesota, the Indiana CTSI has been awarded a grant to facilitate use of All of Us data by health researchers, students, and community partners. According to the All of Us, nearly 500,000 participants have shared a range of data; more than 350,000 have shared electronic medical records; and 474,000 have shared a blood, saliva or urine sample. About 45% of participants self-identify with a racial or ethnic minority group, and 75% identify with communities historically underrepresented in biomedical research.
All of Us offers publicly available aggregate data based on participants’ survey responses, physical measurements, electronic health record information, and wearables data. Researchers and students interested in analyzing individual-level data must register to use the Researcher Workbench platform. Researchers can begin the registration process at http://www.researchallofus.org/CTSA-PACERcommunitynetwork-apply.
Access to the platform is free. However, researchers may need to use cloud computing credits for some analyses. Newly registered researchers receive $300 in initial computational credits to explore the dataset and begin their analysis. The Indiana CTSI Team includes principal investigator, Sarah Wiehe, MD, MPH, co-investigators Kosali Simon, PhD and Jing Su, PhD, program manager Brenda Hudson, MA, data manager Hailemichael Shone, PhD, and data analysts Colin Hoffman, MS and Netsanet Gebregziabher, MS. Additionally, the University of Notre Dame All of Us contact is Jessica Brookshire, MS. The All of Us team provides support to using the All of Us Workbench to Indiana CTSI researchers and students. The Indiana CTSI All of Us Support Team is available to assist with accessing and analyzing data from the All of Us cohort. If you are interested in learning more about how the Indiana CTSI All of Us Support Team can help, please contact us at https://redcap.uits.iu.edu/surveys/?s=TAXT7JA4PJJAXPLM.
The Indiana CTSI contributes to the CTSA/PACER All of Us Community Network in collaboration with the All of Us Research Program’s Division of Engagement and Outreach. The division partners with community organizations nationwide to foster relationships with participants, researchers, and health care providers. The Indiana CTSI initiative and other researcher engagement activities are central to building a diverse community of researchers. There are now more than 6,400 All of Us researchers from all career stages, institution types, backgrounds, and experiences.
The Indiana CTSI All of Us Team will be hosting a presentation on the All of Us Data: what is it, why you may want to use it, and how to access it. This webinar will take place on October 25th from 12 PM – 1 PM. Everyone is welcome to attend. Link to sign up: https://redcap.link/aou