Early Career Investigator Awards (KL2)2021-01-14T09:49:54-05:00

The Indiana CTSI provides funding for special research fellowships for early career investigators in clinical-translational research.

  • These awards are designed to provide promising junior faculty investigators with the opportunity to be mentored in research-intensive, multi-disciplinary settings toward the goal of developing careers in translational research.
  • Translational research is the process of turning observations in the laboratory, clinic, and community into interventions to improve the health of individuals and the public.
  • Emphasis of these awards is to move findings from basic laboratory and pre-clinical research (T1) to the development of new treatment options/interventions or clinical trials (T2) to dissemination/clinical implementation (T3) to studying population health outcomes/health metrics (T4).
  • The goal of the CTSI is to make awards at all of these stages.
  • It is important that the proposed research has clear applications to human disease and health outcomes.

Early Career Investigator Award eligibility requirements

To be eligible, candidates must fall into one of the following categories:

  1. Clinician-scientists with a doctoral degree (physicians, nurses, dentists, pharmacists, clinical psychologists, optometrists, veterinarians, allied health care professionals, etc.)
  2. Basic scientists with a PhD who are doing translational research which involves some component of human subjects research and has high potential for early translation into impacting patient care

Additional eligibility criteria

Early Career Investigator Award candidates must:

  • Be United States citizens or permanent residents
  • Hold a full-time faculty appointment with their institution by start of award
  • Be full-time junior faculty who would be eligible to apply as Principal Investigator on an NIH grant or career development award, but who have not yet been a Principal Investigator on an R01 or equivalent grant
  • Be able to identify co-mentors who are faculty investigators from two different disciplines (preferably a clinician-scientist and a PhD-scientist)
  • Be planning to submit a grant for external funding (either a career development award or independent research grant) during the first 12 months of the award

What are the benefits?

Early Career Investigator Awardees receive:

  • Partial salary support
  • Pilot research monies
  • Travel funds to attend the annual national meeting of the Clinical and Translational Science Awards (CTSA) Program in Washington, D.C.

How to apply

Applications for the Indiana CTSI’s Early Career Investigator Awards are due in January, and awards begin in July of each year. The award is for two years (renewable at the end of year one with satisfactory progress).
Questions? Contact Patricia McGuire at pcmcguir@iu.edu or 317-278-2824.

CTSA KL2 Awardees

Ephrem Abebe Ephrem Abebe, PharmD
Pharmacy Practice, Purdue University
Email: eabebe@purdue.edu
Primary Mentor: Richard Holden, PhD
Co-Mentor: Sarah Wiehe, MD

Title of Project: A Systems Approach to Improve Medication Safety During Care Transitions for Children with Medical Complexity

Michael Bushey Michael Bushey, MD, PhD
Psychiatry, IU School of Medicine
Email: mabushey@iu.edu
Primary Mentor: Kurt Kroenke, MD
Co-Mentor: Alan McGuire, PhD

Title of Project: Collaborative Care for Opioid Dependence and Pain

Allyson Dir Allyson Dir, PhD
Psychiatry, IU School of Medicine
Email: adir@iu.edu
Primary Mentor: Matthew Aalsma, PhD
Co-Mentor: Sarah Wiehe, MD

Title of Project: Utilizing Parent peer Navigators to Increase Parental Engagement in Youth Services: Development and Implementation of an Intervention Among Justice-Involved Youth

Danielle Janosevic Danielle Janosevic, DO
Nephrology, IU School of Medicine
Email: djanosev@iupui.edu
Primary Mentor: Pierre Dagher, MD
Co-Mentor: Kenneth White, PhD

Title of Project: The Spatial and Temporal Signature of Sepsis Associated Acute Kidney Injury

Monica Kasting Monica Kasting, PhD
Health & Kinesiology, Purdue University
Email: mlkastin@purdue.edu
Primary Mentor: Susan Rawl, PhD, RN
Co-Mentor: Cleveland Shields, PhD

Title of Project: Developing an Intervention to Increase Hepatitis C Virus Screening among Baby Boomers in Primary Care

Jennifer Maratt Jennifer Maratt, MD, MS
Digestive and Liver Disease, IU School of Medicine
Email: jmaratt@iu.edu
Primary Mentor: Thomas Imperiale, MD
Co-Mentor: Marianne Matthias, PhD

Title of Project: Improving Endoscopy Efficiency through Patient Engagement

Jennifer Carnahan Jennifer Carnahan, MD, MPH
General Internal Medicine, IU School of Medicine
Email: jenncarn@iupui.edu
Primary Mentor: Alexia Torke, MD
Co-Mentor: Daniel Clark, PhD

Title of Project: The Nurse Intervention to Facilitate Transitions to home Environment (NIFT-E) Study

Andrea Cohee Andrea Cohee, PhD, RN
IU School of Nursing
Email: aamaners@iu.edu
Primary Mentor: Victoria Champion, PhD, RN
Co-Mentor: Patrick Monahan, PhD

Title of Project: Developing the Breast Cancer Self-Efficacy Scale for Partners (BCSES-P)

Hebatullah Ismail Hebatullah Ismail, MD
Pediatrics, IU School of Medicine
Email: Heismail@iu.edu
Primary Mentor: Linda DiMeglio, MD, MPH
Co-Mentor: Carmella Evans-Molina, MD, PhD
Co-Mentor: Cindy Nakatsu, PhD

Title of Project: Prebiotics to Improve and Preserve ß-cell function in Newly-Diagnosed Type 1 Diabetes

April Savoy April Savoy , PhD
Engineering Technology, Computer Information Technology, Purdue University
Email: asavoy@iupui.edu
Primary Mentor: Michael Weiner, MD
Co-Mentor: Teresa Damush, PhD

Title of Project: Closing the Cross-institutional Referral Loop: Applying Human Factors to Improve Consultation Notes

Chen Chen Chen Chen, PhD, RN
IU School of Nursing
Email: cxchen@iu.edu
Primary Mentor: Dennis Fortenberry, MD
Co-Mentor: Janet Carpenter, PhD

Title of Project: Phenotypic Characterization of Dysmenorrhea in Female Adolescents & Young Adults

Sara Honaker Sara Honaker, PhD
Pediatrics, IU School of Medicine
Email: smhonake@iupui.educ
Primary Mentor: Stephen Downs, MD
Co-Mentor: Sarah Wiehe, MD

Title of Project: Development of Health Communication Module for Pediatric Obstructive Sleep Apnea

Stephen Jordan Stephen Jordan, MD, PhD
Infectious Disease, IU School of Medicine
Email: jordansj@iu.edu
Primary Mentor: David Nelson, PhD
Co-Mentor: William Geisler, MD

Title of Project: Role of Interferon-gamma in Clearance of Chlamydia Trachomatis Infection in Women

Joy Lee Joy Lee, PhD
General Internal Medicine, IU School of Medicine
Email: joyllee@iu.edu
Primary Mentor: Michael Weiner, MD
Co-Mentor: Marianne Mathias

Title of Project: Improving Secure Messaging in Primary Care

Carolyn McCormick Carolyn McCormick, PhD
Human Development & Family Studies, Purdue University
Email: mccorm37@purdue.edu
Primary Mentor: Linda Smith, PhD
Co-Mentor: Mandy Rispoli, PhD

Title of Project: Translating Measures of Visual Experience for use in Clinical Trials with Young Children with Autism

Lauren Nephew Lauren Nephew, MD
Gastroenterology, IU School of Medicine
Email: lnephew@iu.edu
Primary Mentor: Naga Chalasani, MD
Co-Mentor: Susan Rawl, PhD

Title of Project: Racial Disparities in Curative Therapies for Hepatocellular Carcinoma

Teresa Bell Teresa Bell, PhD
Surgery, IU School of Medicine
Email: terebell@iupui.edu
Primary Mentor: Aaron Carroll, MD, MS
Co-Mentor: Christopher Harle, PhD, MS

Title of Project: Risk Factors for Prescription Opioid Misuse after Traumatic Injury in Adolescents

Brandon Gufford Brandon Gufford, PharmD, PhD
Clinical Pharmacology, IU School of Medicine
Email: bgufford@iu.edu
Primary Mentor: Zeruesenay Desta, PhD
Co-Mentor: Samir Gupta, MS, MD

Title of Project: Integrative Approaches to Predict Complex Herb-Drug and Drug-Drug Interactions

Anne Krendl Anne Krendl, PhD
Psychological & Brain Sciences, IU-Bloomington
Email: akrendl@indiana.edu
Primary Mentor: Brian D’Onofrio, PhD
Co-Mentor: Kurt Kroenke, MD

Title of Project: Reducing mental health stigma to promote treatment adherence

Xin Lu Xin Lu, PhD
Biological Sciences, Notre Dame
Email: xlu@nd.edu
Primary Mentor: M. Sharon Stack, PhD
Co-Mentor: Liang Cheng, MD

Title of Project: Novel Antibody-Drug Conjugates for Personalized Therapy of Lethal Prostate Cancer

Olena Mazurenko Olena Mazurenko, PhD, MD, MS
Health Policy & Management, IU Public Health
Primary Mentor: Christopher Harle, PhD
Co-Mentor: Matthew Bair, MD, MS

Title of Project: Balancing patient-centeredness and patient safety: the case of pain care and patient satisfaction among hospitalized patients

Takashi Hato Takashi Hato, MD
Medicine, IU School of Medicine
Email: thato@iu.edu
Primary Mentor: Pierre Dagher, MD
Co-Mentor: Kenneth Dunn, PhD

Title of Project: Modulating purine metabolism to treat kidney injury in sepsis.

Kyle S Minor Kyle S. Minor, PhD
Psychology, IUPUI
Email: ksminor@iupui.edu
Primary Mentor: Paul Lysaker, PhD
Co-Mentor: Sarah Wiehe, MD, MPH

Title of Project: Implementing wearable technologies as novel therapeutic tools for Serious Mental Illness.

Marguerite O'Haire Marguerite O’Haire, PhD
Comparative Pathobiology, Purdue University
Email: mohaire@purdue.edu
Primary Mentor: Shelley MacDermid Wadsworth, MBA, PhD
Co-Mentor: Louanne Davis, PsyD, HSPP

Title of Project: Therapeutic efficacy of service dogs for veterans with posttraumatic stress disorder and their spouses

Jenifer Prosperi Jenifer Prosperi, PhD
Biochemistry & Molecular Biology, IU-South Bend
Email: jrprospe@iupui.edu
Primary Mentor: Sharon Stack, PhD
Co-Mentor: Kathy Miller, MD

Title of Project: Targeting APC-mediated pathways to circumvent breast cancer chemoresistance.

Andrea S Shin Andrea S. Shin, MD
Gastroenterology & Hepatology, IU School of Medicine
Email: ashin@iu.edu
Primary Mentor: David Nelson, PhD
Co-Mentor: John Wo, MD

Title of Project: Fecal bile acids, fecal short chain fatty acids and the intestinal microbiota in patients with irritable bowel syndrome (IBS) and control volunteers

Tuan Manh Tran Tuan Manh Tran, MD, PhD
Infectious Disease, IU School of Medicine
Email: tuantran@iu.edu
Primary Mentor: Chandy John, MD, MHS
Co-Mentor: Mark H. Kaplan, PhD

Title of Project: Systems biology approaches to define immunity to Plasmodium falciparum and elucidate the complex host responses during the course of malaria infections

Jill Fodstad Jill Fodstad, PhD, HSPP, BCBA-D
Psychiatry, IU School of Medicine
Email: jfodstad@iupui.edu
Primary Mentor: Noha Minshawi, PhD, HSPP, BCBA-D
Co-Mentor: David Dunn, MD

Title of Project: “Development of a parent-training program to decrease early self-injury in infants and toddlers with intellectual and developmental disabilities”

Craig S Lammert Craig S. Lammert, MD
Gastroenterology, IU School of Medicine
Email: clammert@iu.edu
Primary Mentor: Tatiana Foroud, PhD
Co-Mentor: Naga Chalasni, MD

Title of Project: “Genetic Repository of Autoimmune Liver Diseases and Contributing Exposures (GRACE)”

Troy A Markel Troy A. Markel, MD
Surgery, IU School of Medicine
Email: tmarkel@iupui.edu
Primary Mentor: Mervin Yoder, MD
Co-Mentor: Teresa Zimmers, PhD

Title of Project: “Hydrogen Sulfide is a Key Paracrine Gasotransmitter in Human Bone Marrow Mesenchymal Stem Cell Mediated Intestinal Protection”

Tamika Zapolski Tamika Zapolski, PhD
Psychology, IUPUI
Email: tzapolsk@iupui.edu
Primary Mentor: Matthew Aalsma, PhD
Co-Mentor: Michelle Salyers, PhD

Title of Project: “Modifying and pilot testing a dialectical behavior therapy (DBT) intervention to reduce risk-taking behaviors in adolescents”

Laurie Littlepage Laurie Littlepage, PhD
Chemistry & Biochemistry, Notre Dame
Email: laurie.littlepage@nd.edu
Primary Mentor: Sharon Stack, PhD
Co-Mentor: Sunil Badve, MD

Title of Project: “Overcoming breast cancer chemoresistance using ZNF217 as a prognostic marker and therapeutic target”

Jason Mackey Jason Mackey, MD, MS
Neurology, IU School of Medicine
Email: jmacket3@iuhealth.org
Mentor: Linda Williams, MD
Co-Mentor: Andrew Saykin, PsyD

Title of Project: “Advanced imaging of ongoing vasculopathy in intracerebral hemorrhage”

Eric Orman Eric Orman, MD
Gastroenterology, IU School of Medicine
Email: esorman@iu.edu
Mentor: Naga Chalasani, MD
Co-Mentor: Malaz Boustani, MD, MPH

Title of Project: “Optimizing care for hospitalized patients with cirrhosis: The Midwest cirrhosis consortium”

Ukamaka Oruche Ukamaka Oruche, PhD, RN, PMHCNS-BC
Nursing, IU School of Nursing
Email: uoruche@iu.edu
Mentor: Sheri L. Robb, PhD, MT-BC
Co-Mentor: Matthew Aalsma, PhD

Title of Project: “Developing the Family Management Efficacy (FAME) Intervention for African American Families of Adolescents with Disruptive Behavior Disorders”

Emily Sims Emily Sims, MD
Pediatrics, IU School of Medicine
Email: eksims@iupui.edu
Mentor: Carmella Evans-Molina, MD, PhD
Co-Mentor: Linda DiMeglio, MD, MPH

Title of Project: “B cell derived miR-21 as an intrinsic protective response and biomarker in type 1 diabetes (T1D)”

Timothy W Corson Timothy W. Corson, PhD
Ophthalmology, Indiana University
Email: tcorson@iupui.edu
Primary Mentor: Zhong-Yin Zhang, PhD
Co-Mentor: Douglas Schwartzentruber, MD, FACS

Title of Project: “Targeted degradation of a mutant G-protein as a novel uveal melanoma therapy”

Pascal Jean-Pierre Pascal Jean-Pierre, PhD
Psychology, University of Notre Dame
Email: pjeanpierre@nd.edu
Mentor: Andrew Saykin, PsyD, ABCN
Co-Mentor: Rudolph M. Navari, MD, PhD, FACP

Title of Project: “A Pilot Randomized, Placebo Controlled Trial of Naproxen Sodium to Treat Cancer and Treatment-Related Neurocognitive Dysfunction (CRND) in Breast Cancer (BraCa) Patients Treated with Chemotherapy”

Wendy R Miller Wendy R. Miller, PhD, RN, CCRN
School of Nursing
Email: wrtruebl@indiana.edu
Mentor: Tamilyn Bakas, PhD, Rn, FAHA, FAAN
Co-Mentor: Malaz Boustani, MD, MPH / Janice M. Buelow, PhD, RN, FAAN

Title of Project: “Development of a Tailored Epilepsy Self-Management Intervention for Older Adults”

Brownsyne Tucker Edmonds Brownsyne Tucker Edmonds, MD, MPH, MS
Obstetrics and Gynecology, IUSM
Email: btuckere@iupui.edu
Primary Mentor: Richard Frankel, PhD
Co-Mentor: Lee Learman, MD, PhD

Title of Project: “Using simulation to assess the influence of race and class on periviable counseling among obstetricians and neonatologists.”

Rajashekhar Gangaraju Rajashekhar Gangaraju, PhD
Ophthalmology, IUSM
Email: rgangara@iupui.edu
Mentor: Keith L. March, MD, PHD & Raj K. Maturi, MD
Co-Mentor: Alon Harris, PhD FARVO & Carmella Evans-Molina, MD, PhD

Title of Project: Vascular and neuronal repair with adipose stromal cells in retinopathy: Sight in place of blindness

Shelley Johns Shelley A. Johns, PsyD, ABPP
Medicine, IUSM
Email: sheljohn@iupui.edu
Mentor: Kurt Kroenke, MD
Co-Mentor: Mary DeGroot, PhD

Title of Project: Mindfulness-Based Stress Reduction for Breast Cancer Survivors with Persistent Cancer-Related Fatigue: A Randomized Controlled Trial

Grzegorz Nalepa Grzegorz Nalepa, MD, PhD
Pediatrics, IUSM
Email: gnalepa@iupui.edu
Primary Mentor: D Wade Clapp, MD
Co-Mentor: Zhong-Yin Zhang, PhD

Title of Project: Discovery of druggable phosphatase tumor suppressor signaling network in glioblastoma multiform

Sarah Tersey Sarah Tersey, PhD
Pediatrics, IUSM
Email: stersey@iupui.edu
Primary Mentor: Raghavendra Mirmira
Co-Mentor: Kieren Mather

Title of Project: Role of 12-lipoxygenase in human type 2 diabetes.

Shawn K Ahlfeld Shawn K. Ahlfeld, MD
Pediatrics / Neonatal-Perinatal Medicine, IUSM
Email: skahlfel@iupui.edu
Mentor: Simon Conway, PhD

Assistant Professor of Pediatrics, neonatal-perinatal medicine, IU School of Medicine, will pursue research related to understanding the molecular mechanisms underpinning the development of bronchopulmonary dysplasia (BPD) which is a major cause of morbidity and mortality in premature infants.

Lauren Bell Lauren Bell, PhD
Medicine, Gastroenterology/Hepatology, IU
Email: lnbell@iupui.edu
Mentor: Naga Chalasani, MD

Assistant Research Professor of Medicine, gastroenterology/hepatology, clinical pharmacology and cellular and integrative physiology, IU School of Medicine, will focus on investigating the pathogenesis and treatments for nonalcoholic steatohepatitis (NASH).

Jon Duke Jon Duke, MD, MS
Medicine, General Medicine/Informatics, IUSM
Email: jduke@regenstrief.org
Mentor: Michael Murray, PharmD, MPH

Assistant Professor of Medicine, IU School of Medicine, will explore ways to improve the recognition and management of adverse drug events, particularly in the settings of polypharmacy.

Shoji Ichikawa, PhD
Medicine, Endocrinology, IUSM
Email: ichikawa@iupui.edu
Mentor: Sharon Moe, MD

Assistant Research Professor of Medicine, endocrinology and metabolism, IU School of Medicine, will investigate an effective therapy for a metabolic bone disease named familial tumoral calcinosis.

Philip L Johnson Philip L. Johnson, PhD
Psychiatry, IUSM
Email: philjohn@iupui.edu
Mentor: Todd Skaar, PhD

Assistant Professor of Psychiatry, IU School of Medicine, will explore new non-hormonal or selective hormonal treatments for adverse menopausal symptom clusters.

Elaine Lipscomb Elaine Lipscomb, PhD
Medicine, IUSM
Email: lipscome@iupui.edu
Mentor: Douglas K. Miller, MD

Assistant Research Professor of Medicine, IU School of Medicine, will seek to advance understanding of the comparative effectiveness of obesity, food and nutrition public policies on behavior and obesity-related outcomes across different populations.

Catherine Mosher Catherine Mosher, PhD
Psychology, IUPUI
Email: cemosher@iupui.edu
Mentor: Victoria Champion, PhD, RN, FAAN

Assistant Professor of Psychology, IUPUI, will aim to develop, evaluate and disseminate internet-based interventions to improve the physical and psychological well-being of lung cancer patients and their family caregivers.

Brian Samuels Brian Samuels, MD, PhD
Ophthalmology, IUSM
Email: bcsamuel@iupui.edu
Mentor: Anantha Shekhar, MD, PhD

Assistant Professor of Ophthalmology, IU School of Medicine, will focus on the role of the central nervous system and the progression of glaucoma with the probability of directly translating this research into novel clinical treatment options.

Ragini Vittal Ragini Vittal, PhD
Medicine, Pulmonary, IUSM
Email: rvittal@iupui.edu
Mentor: David S. Wilkes, MD

Assistant Professor of Medicine, IU School of Medicine, will investigate the testing and development of an anti-fibrotic therapeutic agent for the treatment of idiopathic pulmonary fibrosis (IPF).

Zhanxiang Wang Zhanxiang Wang, MD, PhD
Pediatrics, Endocrinology/Diabetes, IUSM
Email: wangz@iupui.edu
Mentor: Debbie Thurmond, PhD

Assistant Research Professor of Pediatrics, diabetes, IU School of Medicine, will study the value of readily available nutritional supplements in restoring or augmenting beta cell function in humans with diabetes.

John P Breinholt John P. Breinholt, MD
Pediatric Cardiology, IUSM
Email: jpbreinh@iupui.edu
Mentor: Michael Sturek, PhD

Assistant Professor of Pediatric Cardiology, IU School of Medicine, will explore developing an animal model to allow evaluation of branch pulmonary artery stenosis and vessel properties after injury.

Laura Hays, PhD
Nursing, IUPUI
Email: lmhays@iupui.edu
Mentor: Ronald T. Ackermann, MD, MPH

Assistant scientist, IU School of Nursing, will develop a group-based adaptation of the Diabetes Prevention Program lifestyle intervention to increase adoption of diabetes risk-reducing behaviors among African American women with pre-diabetes.

Melissa A Kacena Melissa A. Kacena, PhD
Ortho Surgery
Email: mkacena@iupui.edu
Mentor: David Burr, PhD

Assistant professor of orthopaedic surgery, IU School of Medicine, will investigate the mechanism(s) by which megakaryocyte growth factors enhance bone healing.

Julie Otte Julie Otte, PhD, RN, OCN
Nursing
Email: jelam@iupui.edu
Mentor: Todd Skaar, PhD

Assistant Professor of Adult Health, IU School of Nursing, whose research focuses on conducting translational research to examine physiological pathways that link sleep disturbances with other common menopausal symptoms in breast cancer survivors.

Joshua Shrout Joshua Shrout, PhD
Microbiology, Notre Dame
Email: Joshua.shrout@nd.edu
Mentor: Clay Fuqua, PhD

Assistant professor of civil engineering and geological sciences, University of Notre Dame, will focus on studying bacteria, such as Pseudomonas aeruginosa, and how it colonizes and coordinates behavior to establish infections.

Margie Snyder Margie Snyder, PharmD
Pharmacy, Purdue University
Email: snyderme@purdue.edu
Mentor: Brad Doebbeling, MD, MSc, FACP

Assistant Professor of Pharmacy Practice at the Purdue College of Pharmacy will aim to develop community pharmacy-based interventions that enhance patient-centered outcomes while reducing adverse drug events among ambulatory patients.

Brian Decker Brian Decker, MD
Nephrology, IUSM
Mentor: Sharon Moe

Assistant Professor, IUSM Nephrology, will aim to study CYP450-mediated drug metabolism in kidney disease.

Jacob Kean Jacob Kean, PhD
Speech and Hearing Sciences, IUB
Email: jakean@indiana.edu
Mentor: Andrew Saykin, PsyD

Assistant Professor, Speech and Hearing Sciences, will aim to study hyperactivity of the default neuroanatomical network following traumatic brain injury.

Sheri Robb Sheri Robb, PhD
Nursing, IUPUI
shrobb@iu.edu
Mentor: Joan Haase

Assistant Professor, IU School of Nursing, will aim to study music-based interventions for children with cancer.

Erik Imel Erik Imel, MD
Endocrinology, IUSM
Email: eimel@iu.edu
Mentor: Michael Econs

Eric Imel, Assistant Professor, IUSM Endocrinology, will aim to study the role of growth factors in phosphate wasting disorders.

Melissa Carpentier Melissa Carpentier, PhD
Psychology, IU
Email:
Mentor: Vicki Champion

Assistant Professor, Psychology, will aim study community interventions for pediatric cancer survivors.

Rachel Vreeman Rachel Vreeman, MD
Pediatrics, IUSM
Email: rvreeman@iu.edu
Mentor: Edward Leichty

Assistant Professor, IUSM Pediatrics, will aim to study interventions to improve adherence in children with HIV

Martin Were Martin Were, MD
Biomedical Informatics, IUSM
Email: mwere@regenstrief.org
Mentor: William Tierney

Assistant Professor, IUSM, will aim to study interventions to improve patient safety in the hospital.

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