This case series described 3 patients with typical Guillain-Barre Syndrome preceded by symptoms of (and biologically confirmed) COVID-19, with neurological symptoms appearing within the first 22 days of COVID-19 symptoms.
Patients from Geneva and Lausanne University Hospitals, Switzerland, between March and April 2020
All patients presented with distal paresthesias and rapidly progressive limb weakness, evolving to either moderate tetraparesis (n =2) or tetraplegia (n=1) and areflexia (n=3) within the first five days.
- All showed classic demyelinating pattern
- One required mechanical ventilation
Neurological symptoms appeared at 7, 15 and 22 days after the appearance of typical COVID-19 related symptoms
- Initial RT-PCR swab +SAR-CoV-2 on initial swab for two patients, third patient showed seroconversion and a 4th swap was positive.
- All received IVIG
- One patient was discharged, one now walks with assistance, the third is bed-bound but can rise to stand up.