Review: Viral loads in throat and anal swabs in children infected with SARS-CoV-2

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Review: Viral loads in throat and anal swabs in children infected with SARS-CoV-2

Review: Viral loads in throat and anal swabs in children infected with SARS-CoV-2

This retrospective study found inconsistent results of RT-PCR-testing using throat and anal swabs for monitoring SARS-CoV-2 infection.

  • RT-PCR assay on throat and anal swabs were simultaneously tested in 212 of 2138 pediatric patients with suspected SARS-CoV-2 infection in Wuhan Children’s Hospital. 78 of 212 patients were confirmed with SARS-CoV-2 infection according to the positive results obtained from either throat or anal swabs
  • Of the 78 patients, 17 were positive on anal swabs and 37 were positive on throat swabs, as well as 24 were double positive.
  • The diagnostic potential of these two types of specimens showed significant difference (positive rate: 78.2% on throat swabs vs. 52.6% on anal swabs, McNemar Test P = 0.0091) and exhibited a weak positive consistency with Kappa value was 0.311 (P < 0.0001).
  • Viral loads showed no difference and correlation between throat and anal swabs.
  • Further research is needed to determine if there is a fecal-oral route of transmission for SARs-CoV-2
|2020-05-21T08:43:25-04:00May 20th, 2020|COVID-19 Literature|0 Comments

About the Author: Megan McHenry

Megan McHenry

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