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Transgenic and Genome Editing Facility (TGEF)



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Affiliation :  Purdue University

Director:   Judy Hallett

Website:  https://www.purdue.edu/discoverypark/bioscience/facilities/core/transgenic/index.php

Description:
The TGEF Shared Resource is a state-of-the-art facility that offers a large number of services, including the creation of transgenic, gene knock-in and knock-out mouse and rat models for gain-of-function and loss-of-function experiments. Model systems based on transgenic and knock-in/knock-out strategies provide approaches that are developmentally, anatomically and physiologically relevant to human disease, and that can supplement traditional xenograft models for testing new anti-cancer therapies. Genome-edited animal models provide valuable reagents for studies ranging from the regulatory mechanisms governing gene expression patterns to cell-cell interactions, cell cycle control and regulation of signal transduction pathways.

Policies: Services Offered:
  • Mouse/Rat Transgenic Production
  • Mouse/Rat CRISPR-mediated Knock Out Production
  • Mouse/Rat CRISPR-mediated Knock In Production
  • Mouse/Rat Embryo and Sperm Cryopreservation
  • Mouse IVF
  • Mouse/Rat Strain Rederivation
Contact Information:
Judy Hallett
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(765) 496-3352

|2021-04-07T12:52:22-04:00April 7th, 2021|Comments Off on Transgenic and Genome Editing Facility (TGEF)

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