Service Cores

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Service Cores

Indiana CTSI Research Service Cores and Resources

The Indiana CTSI Research Service Cores and Resources are your aid to locate instrumentation and services suited to your research. A listing of a Core’s capabilities, contact information, and website address can be found by clicking their ‘Learn More’ button. All of the Designated Service Cores are eligible for CTSI Core Pilot grants and Post-Doc grants
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IU Indianapolis

Designated Service Core

Behavioral Phenotyping Core (BPC)

The BPC advises upon and/or conducts behavioral experiments in rats or mice. Assays include assessments of general sensory and motor function, cognitive processing, affective reactivity, and PK/PD relationships in drug evaluations.

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Purdue University

Non-Designated Service Resource

Bindley Bioscience Center

Biomolecular technologies, imaging and cytomics, bioinformatics support, and bionanotechnology with an emphasis on nanochemistry and functionalization of nanomaterials.

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Purdue University

Non-Designated Service Resource

Center for Comparative Translational Research

Translational research spans the continuum in which research findings from the researcher’s lab are moved to the patients ‘bedside’ (human) or ‘barn’ (animal). The Center for Comparative Translational Research (CTR) wants to make bridging the gap between benchtop and bedside/barn easier by helping researchers conduct comparative animal studies using induced and spontaneous disease models. It does so by facilitating, coordinating, integrating …

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IU Bloomington

Designated Service Core

CISAB Mechanisms of Behavior Laboratory

The Mechanisms of Behavior Core offers the equipment, reagents, bench space, and expertise to answer questions related to the roles of genetics and hormones in relation to animal behavior.

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IU Indianapolis

Non-Designated Service Resource

Electrophysiology Core

The Electrophysiology Core performs rodent brain slice electrophysiological recordings to measure brain cell function.

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Notre Dame

Designated Service Core

Freimann Life Sciences Center (FLSC)

The Freimann Life Sciences Center is comprised of 2 state-of-the-art animal facilities equipped to house a wide variety of vertebrates. FLSC’s key goals are to support the University of Notre Dame’s teaching and research. The Center is fully accredited by the Association for Assessment and Accreditation of Laboratory Animal Care International.

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IU Indianapolis

Designated Service Core

Genome Editing Center

The Indiana University Genome Editing Center (IUGEC) is a shared resource whose mission is to provide Indiana University and external investigators access to state-of-the-art genome editing technologies by assisting with the generation of genetically modified mouse models and cell lines in a time- and cost-effective manner.

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Purdue University

Designated Service Core

Histology Research Laboratory (HRL)

The Histology Research Laboratory is a full service histology laboratory that provides general histology, immunohistochemistry, frozen sectioning, decalcified and undecalcified bone histology, and slide digitization services. Board certified veterinary pathologists are also available for consultation.

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Purdue University

Designated Service Core

Imaging Facility

The Bioscience Imaging Facility, Purdue University, is a 24hr/7day access core facility specializing in confocal microscopy, multi-photon and light sheet microscopy, pre-clinical molecular and nuclear imaging and computed tomography (mCT) with offline analysis workstations.

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IU Indianapolis

Non-Designated Service Resource

Immunohistochemistry Research Lab (IHC Research Lab)

The Immunohistochemistry Research Lab specializes in assisting researchers with histologic and immunohistochemical labeling of cells or tissue sections as well as collaborations with surgical pathologists.

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IU Indianapolis

Designated Service Core

In Vivo Therapeutics Core (IVT)

The In Vivo Therapeutics Core (IVTC) supports the research and development of safe and more efficacious drug treatment. The IVTC provides cost-effective and comprehensive services including, but not limited to, on-site breeding facilities as well as a numerous in vivo pharmacology models to facilitate the development and testing of novel pharmacological & cellular therapies.

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IU Indianapolis

Designated Service Core

In-Vivo Imaging Core

The In-Vivo Imaging Core provides imaging services for clinical trials, observational, and preclinical studies. We also provide radiochemistry support for molecular imaging. Currently, the Imaging Core is equipped with state-of-the-art imaging systems, including 3T MRI scanners, PET-CT scanners, Bruker 9.4 T preclinical PET-MRI scanner, a Siemens Eclipse Medical Cyclotron, and Radiochemistry Facilities. Highly skilled faculty and staff are available to assist with research …

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Notre Dame

Designated Service Core

Integrated Imaging Facility (NDIIF)

The Notre Dame Integrated Imaging Facility (NDIIF) is a state-of-the-art research core that makes available to the Notre Dame science and engineering community, as well as external customers, an integrated suite of sophisticated microscopes and imaging stations. The NDIIF also provides resident professional staff (three Ph.D.-level imaging specialists and two technicians) to guide the non-expert users. 

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Notre Dame

Non-Designated Service Resource

Keck Center for Transgene Research (resources)

Unique research resources available for collaboration

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IU Indianapolis

Non-Designated Service Resource

Laboratory Animal Resource Center (LARC)

The Laboratory Animal Resource Center (LARC) provides basic husbandry, training, supplies, and specialized service support for medical research at IU School of Medicine.

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IU Bloomington

Designated Service Core

Laboratory Animal Resources (LAR)

LAR provides housing, food, water, bedding, enrichment and medical care for animals housed in LAR animal facilities to be used for research. Research is overseen by an Institutional Animal Care and Use Committee (IACUC) and the Institutional Official and is accredited by AAALAC International and their three primary standards (The Guide for the Care and Use of Laboratory Animals, Guide for the Care and Use of Agricultural Animals in Research and Teaching, and the European …

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IU Indianapolis

Designated Service Core

Multiplex Analysis Core (MAC)

The Multiplex Analysis Core (MAC) offers microplate-based immunoassay systems that can perform multiplex analysis of multiple different analytes in a single sample. The MAC uses a Bio-Plex 200 Multiplex System with High Throughput Fluidics based on Luminex technology.

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Purdue University

Designated Service Core

Pre-Clinical Research Laboratory (PCL)

The Pre-Clinical Research Laboratory (PCL) helps researchers conduct pre-clinical animal research by providing research expertise, technical support, surgical experience, and surgical facilities and equipment. The PCL is a multidisciplinary laboratory where researchers conduct advanced clinical and applied research using induced animal models ranging from rodents to pigs and sheep

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IU Indianapolis

Designated Service Core

Preclinical Modeling and Therapeutics Core (PMTC)

The Preclinical Modeling and Therapeutics Core (PMTC) facilitates the development of pharmacological and cellular therapies for cancer. It provides advanced resources essential for the preclinical validation of novel drug targets and biomarkers of cancer. The PMTC provides expertise in:
• Cellular response technologies
• Breeding of specialized mouse strains
• Tumor modeling
• In vivo therapeutics efficacy & safety testing
• …

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Purdue University

Designated Service Core

Purdue MRI Facility

The Purdue MRI Facility houses two 3T full body MRI systems and one 7T small bore (animal) MRI system that are available for research involving MRI, MR spectroscopy, and other MR applications.

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Purdue University

Designated Service Core

Transgenic and Genome Editing Facility (TGEF)

Offering transgenic and CRISPR-mediated targeted gene editing in mice and rats; gene-targeting in mouse embryonic stem cells (ES) cells; embryo and sperm cryopreservation; in vitro fertilization; rederivation for importation or clean-up of infected lines. Also offering assistance with project design and mouse/rat breeding colony maintenance.

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Purdue University

Designated Service Core

Translational Pharmacology Facility

The PTP Core offers automated blood monitoring in rodents and large animals utilizing stress free sampling through CulexTM technology. We perform a host of services from early lead identification PK and PD assessment through product testing of human formulations in pigs and minipigs, including preclinical formulation development, biodistribution studies, metabolomics analysis, and in vivo toxicological evaluation.

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Purdue University

Non-Designated Service Resource

Veterinary Clinical Trials (VCT)

The Veterinary Clinical Trials Support Service (VCT) facilitates veterinary clinical trials and provides expertise and technical support for translational clinical investigations using animal models of spontaneous, naturally-occurring diseases in client-owned animals and for trials leading to novel drugs or devices.

|2024-03-28T10:47:31-04:00March 28th, 2024|Comments Off on Service Cores

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