Servicecore – Do not remove
Service Cores
Indiana CTSI Research Service Cores and Resources
Purdue University
Bindley Bioscience Center
Biomolecular technologies, imaging and cytomics, bioinformatics support, and bionanotechnology with an emphasis on nanochemistry and functionalization of nanomaterials.
IU Indianapolis
Biochemical Genetics Laboratory
Our laboratory provides clinically validated liquid chromatography tandem mass spectrometry testing for researchers interested in quantifying metabolites in a wide range of biospecimens with a particular focus on amino acid, organic acid, and acylcarnitine analyses.
IU Indianapolis
Bioinformatics Core
The Bioinformatics Core provides advanced computation and informatics approaches to analyze large and complex biological datasets.
Purdue University
Bioinformatics Core
The Bioinformatics Core provides data analysis services for genomics, proteomics and metabolomics data.
Purdue University
Biological Evaluation (BE-SR)
The Biological Evaluation Shared Resource performs highly customizable efficacy testing of novel drug or therapies for antitumor activity. We also acquire blood or tissues for pharmacokinetic or pharmacodynamic analyses.
IU Indianapolis
Biospecimen Collection and Banking Core
The IUSCCC Biospecimen Collection and Banking Core (BC2) provides an extensive collection of well-annotated samples from patients with malignancy and normal controls to support studies exploring the biologic basis of cancer, move basic findings to the clinic, and probe the biology underlying clinical and population phenomena.
IU Indianapolis
Biospecimen Management Core (CTSL/SSF)
The CTSI Biospecimen Management Core consists of the Specimen Storage Facility (SSF) and the Clinical and Translational Support Laboratory (CTSL), which together offer cost efficient sample processing & storage services with a focus on consistent quality and sample integrity.
IU Indianapolis
Biostatistics and Health Data Science Core
The Biostatistics and Health Data Science Core collaborates with investigators in the planning, statistical design, data management, and analysis of health related clinical, laboratory and epidemiological research projects. Grant development assistance is provided without charge.
IU Bloomington
Biostatistics Consulting Center
The Biostatistics Consulting Center provides study design and data analysis for health-related research, including study design, grant or protocol development, sample size and power calculations, data management, data analysis, and scientific writing. Support can range from hourly support on a short-term project to including a biostatistician on a long-term grant collaboration.
IU Indianapolis
Cell and Gene Therapy Manufacturing
The Cell and Gene Therapy Manufacturing (CGTM) Facility collaborates with investigators through all phases of cell and gene therapy manufacturing, from pre-clinical design through treatment of patients. The facility is under the direction of Emily Hopewell, PhD, and comprises the Cell Immunotherapy and Transduction Facility (CIT), the Vector Production Facility (VPF), and the Bioprocess Development and Cell Manufacturing Lab (BDL). Each section of the CGTM is led by a …
Purdue University
Center for Comparative Translational Research
Translational research spans the continuum in which research findings from the researcher’s lab are moved to the patients ‘bedside’ (human) or ‘barn’ (animal). The Center for Comparative Translational Research (CTR) wants to make bridging the gap between benchtop and bedside/barn easier by helping researchers conduct comparative animal studies using induced and spontaneous disease models. It does so by facilitating, coordinating, integrating …
IU Bloomington
Center for Genomics and Bioinformatics (CGB)
The CGB offers a wide range of genomic services, including high-throughput DNA/RNA extraction, library preparation, next-generation sequencing, and bioinformatic analysis.
IU Indianapolis
Center for Proteome Analysis
The IUSM Center for Proteome Analysis provides numerous types of mass-spectrometry based proteomics services, including global proteome quantitation, affinity purification-mass spectrometry, targeted mass spectrometry analysis for precise quantitation, post-translational modification analysis, and a variety of consulting services.
Notre Dame
Center for Research Computing
The CRC houses two complementary resources: the High-Performance Computing section, providing over 35,000 cores of computational power with the associated support infrastructure for both hardware and installed software, and the Cyberinfrastructure section, empowering Faculty and industry partners to develop research software and environments that support advanced data and information processing services including acquisition, storage, management, integration, mining and …
IU Bloomington
Center for Survey Research (CSR)
Leading academic research center providing expert research design, sampling, questionnaire design, interface development and programming, data collection, data processing, and analysis services for wide range of qualitative and quantitative research projects. Partnering on cutting-edge research that involves surveys, interviews, focus groups, or structured observations.
Notre Dame
Center for Zebrafish Research
3,000 sq. ft. facility consisting of 8 double-sided racks and 38 single-sided racks, maintained independently. Separate room houses the nursery.
IU Bloomington
CISAB Mechanisms of Behavior Laboratory
The Mechanisms of Behavior Core offers the equipment, reagents, bench space, and expertise to answer questions related to the roles of genetics and hormones in relation to animal behavior.
IU Indianapolis
Clinical Pharmacology Analytical Core (CPAC)
The Clinical Pharmacology Analytical core provides drug and metabolite concentrations from a variety of biological matrices such as (but not limited to): plasma, urine, CSF, and tissue using HPLC-MS/MS. Additional services include protein binding of drugs, formulation studies, drug stability, drug metabolism, and metabolite screening.
Purdue University
Cryo-EM Facility
The Purdue Cryo-EM facility provides access to state-of-the-art instrumentation enabling users to collect data for high-resolution single particle reconstructions and tomographic studies of cells and larger complexes.
IU Bloomington
Electron Microscopy Center (IUB-EMC)
The IU Bloomington Electron Microscopy Center (IUB-EMC) provides equipment, services and expertise for biological and material science electron microscopy.
Purdue University
Flow Cytometry and Cell Sorting Facility
The Purdue Flow Cytometry Core Facility provides instrumentation, data analysis software, training and technical expertise for flow cytometry analysis and cell sorting. Our capabilities also include the characterization of genome and transcriptomes using the Fluidigm C1 and 10X Genomics systems, in partnership with the Purdue Genomics Core Facility.
Notre Dame
Freimann Life Sciences Center (FLSC)
The Freimann Life Sciences Center is comprised of 2 state-of-the-art animal facilities equipped to house a wide variety of vertebrates. FLSC’s key goals are to support the University of Notre Dame’s teaching and research. The Center is fully accredited by the Association for Assessment and Accreditation of Laboratory Animal Care International.
Notre Dame
Genomics and Bioinformatics Core Facility (GBCF)
The Genomics & Bioinformatics Core Facility (GBCF) at the University of Notre Dame offers comprehensive services and support for state-of-the-art genomics experiments and bioinformatics analysis. This includes next generation Illumina sequencing, a variety of standard and specialty DNA and RNA library construction methods, consultation, and analysis support.
IU Indianapolis
HANDS In Autism Interdisciplinary Training & Resource Center
The HANDS (Helping Answer Needs by Developing Specialists) in Autism® Interdisciplinary Training & Resource Center is located within the Department of Psychiatry at the Indiana University School of Medicine. The HANDS team offers services including:
(1) recruitment,
(2) behavioral, educational, functional, and/or vocational assessment of individuals across a broad range of ages and functioning levels, and
(3) program evaluation efforts targeted to a range …
IU Indianapolis
Histology and Histomorphometry Core (HHC)
Histology and Histomorphetry Core (HHC) provides histological and histomorphometric services for basic science (non-clinical) research. Mineralized (plastic embedded), soft tissue (paraffin embedded), and cryopreserved specimens can be processed by the facility.
Purdue University
Histology Research Laboratory (HRL)
The Histology Research Laboratory is a full service histology laboratory that provides general histology, immunohistochemistry, frozen sectioning, decalcified and undecalcified bone histology, and slide digitization services. Board certified veterinary pathologists are also available for consultation.
IU Indianapolis
Human Vascular Imaging Core (HVIC)
The HVIC performs functional and anatomic vascular imaging measuremetns (flow-mediated dilation and carotid intima-media thickness).
Purdue University
Imaging Facility
The Bioscience Imaging Facility, Purdue University, is a 24hr/7day access core facility specializing in confocal microscopy, multi-photon and light sheet microscopy, pre-clinical molecular and nuclear imaging and computed tomography (mCT) with offline analysis workstations.
IU Bloomington
Imaging Research Facility (IRF)
The IRF is a state-of-the-art neuroimaging facility that enables cutting-edge neuroscience research and training using non-invasive imaging methodologies, including both MRI and EEG.
IU Indianapolis
In Vivo Therapeutics Core (IVT)
The In Vivo Therapeutics Core (IVTC) supports the research and development of safe and more efficacious drug treatment. The IVTC provides cost-effective and comprehensive services including, but not limited to, on-site breeding facilities as well as a numerous in vivo pharmacology models to facilitate the development and testing of novel pharmacological & cellular therapies.
IU Indianapolis
In-Vivo Imaging Core
The In-Vivo Imaging Core provides imaging services for clinical trials, observational, and preclinical studies. We also provide radiochemistry support for molecular imaging. Currently, the Imaging Core is equipped with state-of-the-art imaging systems, including 3T MRI scanners, PET-CT scanners, Bruker 9.4 T preclinical PET-MRI scanner, a Siemens Eclipse Medical Cyclotron, and Radiochemistry Facilities. Highly skilled faculty and staff are available to assist with research …
IU Indianapolis
Indiana Center for Biological Microscopy (ICBM)
The ICBM provides researchers with access to laser-scanning confocal, 2-photon and epi-fluorescence microscopes (http://www.medicine.iupui.edu/ICBM/USING-THE-FACILITY). Center personnel train individual researchers to use all imaging systems and provide expert help in the design, conduct and analysis of imaging studies. As necessary, center personnel can also be hired to conduct microscopy studies for laboratories lacking the necessary expertise.
Notre Dame
Integrated Imaging Facility (NDIIF)
The Notre Dame Integrated Imaging Facility (NDIIF) is a state-of-the-art research core that makes available to the Notre Dame science and engineering community, as well as external customers, an integrated suite of sophisticated microscopes and imaging stations. The NDIIF also provides resident professional staff (three Ph.D.-level imaging specialists and two technicians) to guide the non-expert users.
IU Indianapolis
Investigational Agent Acquisition Program
Goal: The goal of the CTSI Investigational Agent Acquisition Program (IAAP) is to assist CTSI investigators seeking investigational agents for use in clinical trials.
Scope: The IAAP program will assist in acquiring drugs, neutraceuticals, biologics or other materials to be used in a Investigational New Drug Application or IND-exempt clinical trial.
Eligibility: Any faculty within the CTSI member institutions.
Overview: Moving bench research into …
IU Indianapolis
Islet and Physiology Core
The Islet and Physiology Core of the Center for Diabetes and Metabolic Diseases provides investigators with the capability to obtain high quality rodent pancreatic islets for study. The Core also provides services for islet transplantation and will assist investigators who wish to perform immunohistochemistry, immunofluorescence, and/or analysis of beta cell mass on whole pancreata from mouse and rat models.
IU Indianapolis
IU School of Medicine Center for Electron Microscopy (iCEM)
The Indiana University School of Medicine Electron Microscopy Center is a full service research laboratory providing both Transmission and Scanning Electron Microscopy. The service provided can apply both traditional methods and recent technical developments to suit the investigator’s needs.
IU Indianapolis
Laboratory Animal Resource Center (LARC)
The Laboratory Animal Resource Center (LARC) provides basic husbandry, training, supplies, and specialized service support for medical research at IU School of Medicine.
IU Bloomington
Laboratory Animal Resources (LAR)
LAR provides housing, food, water, bedding, enrichment and medical care for animals housed in LAR animal facilities to be used for research. Research is overseen by an Institutional Animal Care and Use Committee (IACUC) and the Institutional Official and is accredited by AAALAC International and their three primary standards (The Guide for the Care and Use of Laboratory Animals, Guide for the Care and Use of Agricultural Animals in Research and Teaching, and the European …
Purdue University
Life Science Microscopy Facility
The Life Science Microscopy Facility (LSMF) is an electron microscopy core with both service and individual use options.
IU Bloomington
Light Microscopy Imaging Center (LMIC)
The LMIC provides access and training for confocal and super-resolution light microscopy systems with support for experimental design and data visualization.
Notre Dame
Magnetic Resonance Research Center
The Magnetic Resonance Research Center (MRRC) supports research in chemistry, biochemistry, molecular biology, engineering and related fields. The MRRC operates six solution-state NMR spectrometers (400 to 800 MHz), a solid-state 300 MHz NMR instrument, and an X-band EPR spectrometer. Most instruments are equipped with sample changers for increased sample throughput. See the MRRC website for more information.
Purdue University
Metabolite Profiling Facility (MPF)
The Metabolite Profiling Facility (MPF) provides both qualitative (comparative analysis) and quantitative (absolute concentrations) metabolite chemical analysis in complex biological systems.
IU Indianapolis
Multiplex Analysis Core (MAC)
The Multiplex Analysis Core (MAC) offers microplate-based immunoassay systems that can perform multiplex analysis of multiple different analytes in a single sample. The MAC uses a Bio-Plex 200 Multiplex System with High Throughput Fluidics based on Luminex technology.
IU Bloomington
NMR Facility
The NMR Facility offers solution NMR spectroscopy services for small and large molecules.
Purdue University
Pharmaceutical Manufacturing Core Facility
Pharmaceutical Manufacturing Core Facility provides support and capabilities for a wide range of research in pharmaceutical development and manufacturing. Technical support for the Facility is provided by the faculty of Industrial and Physical Pharmacy who have extensive pharmaceutical manufacturing experience in both industrial and academic environments.
Purdue University
Pre-Clinical Research Laboratory (PCL)
The Pre-Clinical Research Laboratory (PCL) helps researchers conduct pre-clinical animal research by providing research expertise, technical support, surgical experience, and surgical facilities and equipment. The PCL is a multidisciplinary laboratory where researchers conduct advanced clinical and applied research using induced animal models ranging from rodents to pigs and sheep
IU Indianapolis
Preclinical Innovation Think Tanks
Indiana CTSI Think Tanks are an opportunity for researchers at any of the Indiana CTSI campuses of Indiana University (IU), Purdue University and the University of Notre Dame to get help advancing their discoveries to the market. The Drug and Device Think Tanks each serve as a one-stop shop where investigators can receive guidance from a pool of advisors with a wide range of scientific, technical, clinical, business, and regulatory expertise.
IU Indianapolis
Preclinical Modeling and Therapeutics Core (PMTC)
The Preclinical Modeling and Therapeutics Core (PMTC) facilitates the development of pharmacological and cellular therapies for cancer. It provides advanced resources essential for the preclinical validation of novel drug targets and biomarkers of cancer. The PMTC provides expertise in:
• Cellular response technologies
• Breeding of specialized mouse strains
• Tumor modeling
• In vivo therapeutics efficacy & safety testing
• …
Purdue University
Proteomics Facility
The Purdue Proteomics Facility provides chromatography, mass spectrometry and bioinformatic resources for the research communities on campus and beyond for protein characterization. These services include protein identification, relative and absolute quantitation, mapping post-translational modifications, and discovering new protein complexes and protein-protein interactions from a wide variety of sample types such as gel bands, cell or tissue lysates, and plasma or …
IU Indianapolis
Regenstrief Data Services
Services RDS offerings include, but are not limited to:
• Feasibility
• DIY: i2b2
• Cohorts
• Recruitment Lists
• Registries
• Patient Lists
• Geocoding
• Phenotyping
• Deidentification
• EHR Integration/Innovation
• Application Development
• Application Prototypes
• Natural Language Processing (NLP)
• Data Linkage
• Machine Learning Models …
IU Indianapolis
Research Jam
Research Jam is an interdisciplinary team of healthcare, research, and design professionals. The team uses human-centered design research to collaborate with doctors, patients, and community members in an effort to ensure that health research, interventions, and communications are more relevant to the community they aim to serve. By engaging stakeholders in a co-design process, they are able to assist clients with recruitment strategies, study retention, and protocol …
IU Indianapolis
SNRI Biomarker Core
The Stark Neurosciences Research Institute Biomarker Core provides biomarker services to investigators. Multiplexing of targets in tissues or on a slide, investigators can detect changes in their samples and target specific pathways of interest in disease.
Purdue University
Translational Pharmacology Facility
The PTP Core offers automated blood monitoring in rodents and large animals utilizing stress free sampling through CulexTM technology. We perform a host of services from early lead identification PK and PD assessment through product testing of human formulations in pigs and minipigs, including preclinical formulation development, biodistribution studies, metabolomics analysis, and in vivo toxicological evaluation.
Purdue University
Veterinary Clinical Trials (VCT)
The Veterinary Clinical Trials Support Service (VCT) facilitates veterinary clinical trials and provides expertise and technical support for translational clinical investigations using animal models of spontaneous, naturally-occurring diseases in client-owned animals and for trials leading to novel drugs or devices.