Service Cores

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Service Cores

Indiana CTSI Research Service Cores and Resources

The Indiana CTSI Research Service Cores and Resources are your aid to locate instrumentation and services suited to your research. A listing of a Core’s capabilities, contact information, and website address can be found by clicking their ‘Learn More’ button. All of the Designated Service Cores are eligible for CTSI Core Pilot grants and Post-Doc grants
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Purdue University

Non-Designated Service Resource

Bindley Bioscience Center

Biomolecular technologies, imaging and cytomics, bioinformatics support, and bionanotechnology with an emphasis on nanochemistry and functionalization of nanomaterials.

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Purdue University

Non-Designated Service Resource

Bioinformatics Core

The Bioinformatics Core provides data analysis services for genomics, proteomics and metabolomics data.

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IU Indianapolis

Designated Service Core

Bioinformatics Core

The Bioinformatics Core provides advanced computation and informatics approaches to analyze large and complex biological datasets.

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IU Indianapolis

Designated Service Core

Biospecimen Collection and Banking Core

The IUSCCC Biospecimen Collection and Banking Core (BC2) provides an extensive collection of well-annotated samples from patients with malignancy and normal controls to support studies exploring the biologic basis of cancer, move basic findings to the clinic, and probe the biology underlying clinical and population phenomena. 

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IU Indianapolis

Designated Service Core

Biostatistics and Health Data Science Core

The Biostatistics and Health Data Science Core collaborates with investigators in the planning, statistical design, data management, and analysis of health related clinical, laboratory and epidemiological research projects. Grant development assistance is provided without charge.

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IU Indianapolis

Designated Service Core

Cellular Response Technologies Core

Conduct validated and highly reproducible in vitro and in vivo angiogenesis, endothelial, hematopoietic and multi-parametric flow cytometry assays and their role in normal and patient-related hematologic and cardiovascular disorders. The ABC also manages an IncuCyte Zoom and Seahorse XFp.

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Purdue University

Non-Designated Service Resource

Center for Comparative Translational Research

Translational research spans the continuum in which research findings from the researcher’s lab are moved to the patients ‘bedside’ (human) or ‘barn’ (animal). The Center for Comparative Translational Research (CTR) wants to make bridging the gap between benchtop and bedside/barn easier by helping researchers conduct comparative animal studies using induced and spontaneous disease models. It does so by facilitating, coordinating, integrating …

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IU Indianapolis

Designated Service Core

Clinical Pharmacology Analytical Core (CPAC)

The Clinical Pharmacology Analytical core provides drug and metabolite concentrations from a variety of biological matrices such as (but not limited to): plasma, urine, CSF, and tissue using HPLC-MS/MS. Additional services include protein binding of drugs, formulation studies, drug stability, drug metabolism, and metabolite screening.

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IU Bloomington

Designated Service Core

Flow Cytometry Core Facility (FCCF)

The IU-B FCCF provides flow cytometry analysis, sorting and cell counting services, access to flow cytometry data analysis software, assistance with experimental design, and houses a mobile (on a cart) flow cytometry analyzer and a large particle sorter.

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IU Indianapolis

Designated Service Core

Flow Cytometry Resource Facility (FCRF)

The Flow Cytometry Resource Facility (FCRF) provides flow cytometric analysis and cell sorting services as well as flow cytometric image analysis.

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IU Indianapolis

Designated Service Core

Histology and Histomorphometry Core (HHC)

Histology and Histomorphetry Core (HHC) provides histological and histomorphometric services for basic science (non-clinical) research. Mineralized (plastic embedded), soft tissue (paraffin embedded), and cryopreserved specimens can be processed by the facility.

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IU Indianapolis

Non-Designated Service Resource

Human Vascular Imaging Core (HVIC)

The HVIC performs functional and anatomic vascular imaging measuremetns (flow-mediated dilation and carotid intima-media thickness).

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IUSM South Bend

Designated Service Core

Imaging and Flow Cytometry Core Facility

Standard confocal or multiphoton resources for imaging live or fixed samples and a 5 color flow cytometric analyzer are available. Data analysis software for each resource is also available on site.

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Purdue University

Designated Service Core

Imaging Facility

The Bioscience Imaging Facility, Purdue University, is a 24hr/7day access core facility specializing in confocal microscopy, multi-photon and light sheet microscopy, pre-clinical molecular and nuclear imaging and computed tomography (mCT) with offline analysis workstations.

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IU Indianapolis

Non-Designated Service Resource

Immunohistochemistry Research Lab (IHC Research Lab)

The Immunohistochemistry Research Lab specializes in assisting researchers with histologic and immunohistochemical labeling of cells or tissue sections as well as collaborations with surgical pathologists.

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IU Indianapolis

Designated Service Core

In Vivo Therapeutics Core (IVT)

The In Vivo Therapeutics Core (IVTC) supports the research and development of safe and more efficacious drug treatment. The IVTC provides cost-effective and comprehensive services including, but not limited to, on-site breeding facilities as well as a numerous in vivo pharmacology models to facilitate the development and testing of novel pharmacological & cellular therapies.

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IU Indianapolis

Designated Service Core

In-Vivo Imaging Core

The In-Vivo Imaging Core provides imaging services for clinical trials, observational, and preclinical studies. We also provide radiochemistry support for molecular imaging. Currently, the Imaging Core is equipped with state-of-the-art imaging systems, including 3T MRI scanners, PET-CT scanners, Bruker 9.4 T preclinical PET-MRI scanner, a Siemens Eclipse Medical Cyclotron, and Radiochemistry Facilities. Highly skilled faculty and staff are available to assist with research …

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IU Indianapolis

Designated Service Core

Indiana Center for Biological Microscopy (ICBM)

The ICBM provides researchers with access to laser-scanning confocal, 2-photon and epi-fluorescence microscopes (http://www.medicine.iupui.edu/ICBM/USING-THE-FACILITY).  Center personnel train individual researchers to use all imaging systems and provide expert help in the design, conduct and analysis of imaging studies.  As necessary, center personnel can also be hired to conduct microscopy studies for laboratories lacking the necessary expertise.

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IU Indianapolis

Designated Service Core

Islet and Physiology Core

The Islet and Physiology Core of the Center for Diabetes and Metabolic Diseases provides investigators with the capability to obtain high quality rodent pancreatic islets for study.  The Core also provides services for islet transplantation and will assist investigators who wish to perform immunohistochemistry, immunofluorescence, and/or analysis of beta cell mass on whole pancreata from mouse and rat models. 

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Notre Dame

Designated Service Core

Mass Spectrometry and Proteomics Facility

Analysis of large and small molecules using several ionization methods, low or high resolution, hyphenated techniques, proteomics, and metabolomics.

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IU Bloomington

Non-Designated Service Resource

Mass Spectrometry Facility

The Indiana University Mass Spectrometry Facility (MSF) provides qualitative and quantitative small molecule mass spectrometry data. It also confirms chemical formulae of novel compounds by accurate mass spectrometry.

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IU Indianapolis

Designated Service Core

Multiplex Analysis Core (MAC)

The Multiplex Analysis Core (MAC) offers microplate-based immunoassay systems that can perform multiplex analysis of multiple different analytes in a single sample. The MAC uses a Bio-Plex 200 Multiplex System with High Throughput Fluidics based on Luminex technology.

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IU Bloomington

Designated Service Core

NMR Facility

The NMR Facility offers solution NMR spectroscopy services for small and large molecules.

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IU Bloomington

Non-Designated Service Resource

Oxidative Stress and Environmental Analysis Core

The Oxidative Stress Environmental Analysis Core laboratory has established a number of measurements for assessing oxidative stress and damage in a variety of biological samples with excellent accuracy and reproducibly using state of the art LC-MSMS, GC, and PCR equipment.

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IU Bloomington

Non-Designated Service Resource

Physical and Biochemistry Instrumentation Facility (PBIF)

The PBIF provides resources to characterize particle properties as well as macromolecular interactions.

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Purdue University

Designated Service Core

Pre-Clinical Research Laboratory (PCL)

The Pre-Clinical Research Laboratory (PCL) helps researchers conduct pre-clinical animal research by providing research expertise, technical support, surgical experience, and surgical facilities and equipment. The PCL is a multidisciplinary laboratory where researchers conduct advanced clinical and applied research using induced animal models ranging from rodents to pigs and sheep

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IU Indianapolis

Designated Service Core

Preclinical Modeling and Therapeutics Core (PMTC)

The Preclinical Modeling and Therapeutics Core (PMTC) facilitates the development of pharmacological and cellular therapies for cancer. It provides advanced resources essential for the preclinical validation of novel drug targets and biomarkers of cancer. The PMTC provides expertise in:
• Cellular response technologies
• Breeding of specialized mouse strains
• Tumor modeling
• In vivo therapeutics efficacy & safety testing
• …

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Purdue University

Designated Service Core

Proteomics Facility

The Purdue Proteomics Facility provides chromatography, mass spectrometry and bioinformatic resources for the research communities on campus and beyond for protein characterization. These services include protein identification, relative and absolute quantitation, mapping post-translational modifications, and discovering new protein complexes and protein-protein interactions from a wide variety of sample types such as gel bands, cell or tissue lysates, and plasma or …

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IU Indianapolis

Non-Designated Service Resource

SNRI Biomarker Core

The Stark Neurosciences Research Institute Biomarker Core provides biomarker services to investigators. Multiplexing of targets in tissues or on a slide, investigators can detect changes in their samples and target specific pathways of interest in disease. 

|2024-03-28T10:47:31-04:00March 28th, 2024|Comments Off on Service Cores

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