Clinical characteristics

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This article identifies the characteristics of COVID-19 related deaths in a sample population from Italy, describing the clinical course and phenotype of these COVID-19 related deaths in the hospital of young adults (age < 65) as compared to older adults Read More
This article features both a meta-analysis and systematic review on the clinical features of pediatric inpatients with SARS-CoV-2 infection. The authors searched reputable libraries for observational studies and case series to identify clinical features and details on pediatric patients who Read More
Published on :  | By Megan McHenry

Review: Predictors for severe COVID-19 infection

This retrospective chart review found that 1) acute/pre-existing renal disease; 2) oxygen requirement at the time of hospitalization; and 3) initial C-reactive protein were independent predictors for the development of severe COVID19 infections.  A  single-center, retrospective observational study, which included Read More
This case series described 3 patients with typical Guillain-Barre Syndrome preceded by symptoms of (and biologically confirmed) COVID-19, with neurological symptoms appearing within the first 22 days of COVID-19 symptoms.  Patients from Geneva and Lausanne University Hospitals, Switzerland, between March Read More
This case series found hospitalized pediatric patients infected with COVID-19 were significantly younger; more likely to have an underlying comorbidity or coinfection, and more likely to report fever and dyspnea, compared to non-hospitalized COVID-19 pediatric patients. Pediatric patients also likely Read More
Published on :  | By Laramie Mack

Review: COVID-19 and older adults: What we know

This is an overview of COVID-19 in older adults, who are more likely to be infected with the virus and have worse outcomes of COVID-19. Pathophysiology: Angiotensin-converting enzyme-2 (ACE-2) receptor may be a mechanism for cell entry. Since a large Read More
In this study, the diagnosis of influenza-like illness trends with both influenza (which was decreasing up until March) and COVID-19  (which began sharply increasing in March). In 3 of the 4 regions of New York State (not including NYC), the Read More
This retrospective cohort study found that 76.9% of the patients who were hospitalized with Covid-19 and 70.6% of those who died were black, whereas blacks comprise only 31% of the Ochsner Health population (in Louisiana.)  Study occurred within a integrated-delivery Read More
This study systematically analyzed key immunological parameters spanning the course of infection, obtained viral genomes directly from clinical samples, and delineated factors associated with prognosis and epidemiological features. Authors analyzed the clinical, molecular and immunological data from 326 confirmed cases Read More
This meta-analysis found that individuals with either severe cases or non-surviving cases of COVID-19 had lower platelet counts compared to individuals with non-severe and surviving cases, suggesting that thrombocytopenia may be a risk factor for COVID-19 progressing into a more Read More

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