clinical research

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Clinical Characteristics Within a cohort study of 1641 adult patients with SARS-CoV-2, an elevated red blood cell distribution width (RDW) at admission and increasing RDW during hospitalization were associated with statistically higher increased in mortality risk.   Within this meta-analysis Read More
Clinical Characteristics: Within this surveillance cohort of 598 hospitalized pregnant women with COVID-19, 55% were asymptomatic at admission. Among these pregnant women, 2% had pregnancy losses during COVID-19-associated hospitalizations and were experienced by both symptomatic and asymptomatic women. Inflammation: Within Read More
Clinical Characteristics In this case series of 91 children who tested positive for COVID-19 in Korea, 22% were asymptomatic. These children were tested for COVID-19 when they had a history of close contact with confirmed cases. Only 8.5% of symptomatic Read More
Clinical Characteristics This prospective observational cohort study describes the clinical characteristics of 651 children and adolescents from England, Wales, and Scotland, of which 52 met WHO criteria for MIS-C. In addition to the WHO diagnostic criteria, children with MIS-C were Read More
Transmission A small study of 18 breastfeeding women with COVID-19 found that SARS-CoV-2 RNA was found in only one sample, and a viral culture from that sample was negative. This suggests that breast milk is an unlikely source of infection Read More
Personal Protective Equipment A quality improvement study looking at comparative fitted filtration efficiencies for various mask styles found N95 makes had efficiencies of 98.%; surgical mask with ties was 71.5%; procedure mask with ear loops was 38.1%. Used and/or expired Read More
Clinical Testing and Evaluations In a cohort of 145 patients with mild to moderate COVID-19 illness, replication of SARS-CoV-2 in older children led to similar levels of viral RNA as adults, but significantly greater amounts are detected in children younger Read More
Vaccine Update:  The mRNA-1273 vaccine (from Moderna and NIAID) induced anti-SARS-COV-2 immune responses (anti-Spike-2P glycoprotein antibody) in all participants and no trial-limiting safety concerns were identified. Epidemiology: During hospital-wide SARS-CoV-2 antibody (Ab) screening in healthcare workers (HCW) and staff in Read More

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