Hydroxychloroquine

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Clinical characteristics and lab results to predict severity of infection In this retrospective study, authors attempt to identify early clinical and laboratory factors that may predict severe COVID-19 infection. Two cohorts were designed among 198 patients to designate those with Read More
The Moral Determinants of Health – legendary health care researcher Donald Berwick authors a Viewpoint in the Journal of the American Medical Association arguing for health professionals and systems embracing the moral determinants of health, including a “strong sense of Read More
This randomized trial showed that hydroxychloroquine did not prevent presumed/confirmed COVID-19 when used as post-exposure prophylaxis within 4 days of high- or moderate-risk COVID-19 exposure. This randomized, double-blind, placebo-controlled trial occurred across the United States and parts of Canada Enrolled Read More
THE ARTICLE DISCUSSED HAS BEEN RETRACTED. CLICK HERE TO SEE THE RETRACTION NOTICE. A multinational registry analysis found no evidence of benefit of hydroxychloroquine or chloroquine when used either alone or with a macrolide.  Using an international, observational registry across Read More
Among 1438 patients hospitalized with COVID-19 in metropolitan New York in this publication, treatment with hydroxychloroquine, azithromycin, or both was not associated with significantly lower in-hospital mortality. A retrospective study aimed to describe the association between use of hydroxychloroquine, with Read More
This analysis from experts on the ethics of pandemic drug and vaccine research raises significant concerns about promoting the use of unproven off-label uses drugs as part of COVID-19 response efforts. While acknowledging there is limited evidence for its effectiveness, Read More

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