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Service Cores

Indiana CTSI Research Service Cores and Resources

The Indiana CTSI Research Service Cores and Resources are your aid to locate instrumentation and services suited to your research. A listing of a Core’s capabilities, contact information, and website address can be found by clicking their ‘Learn More’ button. All of the Designated Service Cores are eligible for CTSI Core Pilot grants and Post-Doc grants
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IU Indianapolis

Designated Service Core

Advanced Biomedical IT Core

Provide software and technology solutions for research, especially for projects that involve electronic protected health information (ePHI).

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IU Indianapolis

Designated Service Core

Behavioral Phenotyping Core (BPC)

The BPC advises upon and/or conducts behavioral experiments in rats or mice. Assays include assessments of general sensory and motor function, cognitive processing, affective reactivity, and PK/PD relationships in drug evaluations.

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Purdue University

Non-Designated Service Resource

Bindley Bioscience Center

Biomolecular technologies, imaging and cytomics, bioinformatics support, and bionanotechnology with an emphasis on nanochemistry and functionalization of nanomaterials.

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IU Indianapolis

Non-Designated Service Resource

Biochemical Genetics Laboratory

Our laboratory provides clinically validated liquid chromatography tandem mass spectrometry testing for researchers interested in quantifying metabolites in a wide range of biospecimens with a particular focus on amino acid, organic acid, and acylcarnitine analyses.

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IU Indianapolis

Designated Service Core

Bioinformatics Core

The Bioinformatics Core provides advanced computation and informatics approaches to analyze large and complex biological datasets.

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Purdue University

Non-Designated Service Resource

Bioinformatics Core

The Bioinformatics Core provides data analysis services for genomics, proteomics and metabolomics data.

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Purdue University

Designated Service Core

Biological Evaluation (BE-SR)

The Biological Evaluation Shared Resource performs highly customizable efficacy testing of novel drug or therapies for antitumor activity. We also acquire blood or tissues for pharmacokinetic or pharmacodynamic analyses.

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Notre Dame

Non-Designated Service Resource

Biophysics Instrumentation Core (BIC) Facility

The BIC Facility offers sophisticated instrumentation dedicated to characterizing biomolecular conformations and interactions, as well as equipment for the isolation and purification of macromolecules for subsequent detailed biophysical analysis.

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IU Indianapolis

Designated Service Core

Biospecimen Management Core (CTSL/SSF)

The CTSI Biospecimen Management Core consists of the Specimen Storage Facility (SSF) and the Clinical and Translational Support Laboratory (CTSL), which together offer cost efficient sample processing & storage services with a focus on consistent quality and sample integrity.

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IU Bloomington

Designated Service Core

Biostatistics Consulting Center

The Biostatistics Consulting Center provides study design and data analysis for health-related research, including study design, grant or protocol development, sample size and power calculations, data management, data analysis, and scientific writing. Support can range from hourly support on a short-term project to including a biostatistician on a long-term grant collaboration.

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IU Indianapolis

Designated Service Core

Biostatistics Core

The Biostatistics Core collaborates with investigators in the planning, statistical design, data management, and analysis of health related clinical, laboratory and epidemiological research projects. Grant development assistance is provided without charge.

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Purdue University

Non-Designated Service Resource

Birck Nanotechnology Center

Nanofabrication cleanroom, bio-pharma clean room, nanometrology laboratories, nanomanufacturing laboratories, microelectronics and microfuidics fabrication and testing laboratories, 3D cell culture and tissue chip laboratories

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Purdue University

Non-Designated Service Resource

Bone and Body Composition Core

The Bone and Body Composition Core provides services and methods of determining bone density, bone geometry and body composition in humans and small animals. The core provides technical services and includes tissue processors, microtomes, and several microscopes with software for capturing histomorphometric measurements. The core can provide training and access to these machines.

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IU Indianapolis

Non-Designated Service Resource

Cell and Gene Therapy Manufacturing

The Cell and Gene Therapy Manufacturing (CGTM) Facility collaborates with investigators through all phases of cell and gene therapy manufacturing, from pre-clinical design through treatment of patients. The facility is under the direction of Emily Hopewell, PhD, and comprises the Cell Immunotherapy and Transduction Facility (CIT), the Vector Production Facility (VPF), and the Bioprocess Development and Cell Manufacturing Lab (BDL). Each section of the CGTM is led by a …

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IU Indianapolis

Designated Service Core

Cellular Response Technologies Core

Conduct validated and highly reproducible in vitro and in vivo angiogenesis, endothelial, hematopoietic and multi-parametric flow cytometry assays and their role in normal and patient-related hematologic and cardiovascular disorders. The ABC also manages an IncuCyte Zoom and Seahorse XFp.

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Purdue University

Non-Designated Service Resource

Center for Comparative Translational Research

Translational research spans the continuum in which research findings from the researcher’s lab are moved to the patients ‘bedside’ (human) or ‘barn’ (animal). The Center for Comparative Translational Research (CTR) wants to make bridging the gap between benchtop and bedside/barn easier by helping researchers conduct comparative animal studies using induced and spontaneous disease models. It does so by facilitating, coordinating, integrating and stimulating …

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IU Bloomington

Non-Designated Service Resource

Center for Evaluation, Policy, and Research (CEPR)

CEPR provides rigorous, high-quality, non-partisan evaluation, policy analyses, and research for meaningful, useful, and actionable data for clients and project stakeholders. Clients include international, federal and state agencies, public and private organizations, and foundations and endowments working across a range of fields and disciplines.

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IU Bloomington

Designated Service Core

Center for Genomics and Bioinformatics (CGB)

The CGB offers a wide range of genomic services, including high-throughput DNA/RNA extraction, library preparation, next-generation sequencing, and bioinformatic analysis.

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IU Indianapolis

Designated Service Core

Center for Medical Genomics (CMG)

The Center for Medical Genomics provides high-throughput genomics services including: genomic DNA sequencing, transcriptome RNA sequencing, miRNA sequencing, methylome or targeted methylation sequencing, protein DNA/RNA interaction (ChIP-seq, ATAC-seq and CLIP-seq), 10x single cell or single nuclei sequencing, and SNP genotyping.

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IU Indianapolis

Designated Service Core

Center for Proteome Analysis

The IUSM Center for Proteome Analysis provides numerous types of mass-spectrometry based proteomics services, including global proteome quantitation, affinity purification-mass spectrometry, targeted mass spectrometry analysis for precise quantitation, post-translational modification analysis, and a variety of consulting services.

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Notre Dame

Non-Designated Service Resource

Center for Research Computing

The CRC houses two complementary resources: the High-Performance Computing section, providing over 35,000 cores of computational power with the associated support infrastructure for both hardware and installed software, and the Cyberinfrastructure section, empowering Faculty and industry partners to develop research software and environments that support advanced data and information processing services including acquisition, storage, management, integration, mining and …

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IU Bloomington

Designated Service Core

Center for Survey Research (CSR)

Leading academic research center providing expert research design, sampling, questionnaire design, interface development and programming, data collection, data processing, and analysis services for wide range of qualitative and quantitative research projects. Partnering on cutting-edge research that involves surveys, interviews, focus groups, or structured observations.

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Notre Dame

Non-Designated Service Resource

Center for Zebrafish Research

3,000 sq. ft. facility consisting of 8 double-sided racks and 38 single-sided racks, maintained independently. Separate room houses the nursery.

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IU Indianapolis

Designated Service Core

Chemical Genomics Core Facility

The Core aims to provide sophisticated high-throughput screening, high content analysis, small molecule inhibitor design and synthesis, characterization, structural elucidation, qualification and quantification from small molecule to large protein to Indiana University investigators and industrial researchers as well.

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Purdue University

Designated Service Core

Chemical Genomics Facility (CGF)

The Chemical Genomics Facility (CGF) provides affordable access to large chemical and CRISPR libraries and state-of-the-art instrumentation in high-throughput screening (HTS) and high content screening (HCS) campaigns to facilitate the identification of chemical or genomic tools to study biological pathways and the discovery of lead agents for the development of novel therapeutics and diagnostic approaches. The facility also provides assistance in assay development and hit …

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IU Indianapolis

Non-Designated Service Resource

Chemical Synthesis and Organic Drug Lead Development

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IU Bloomington

Designated Service Core

CISAB Mechanisms of Behavior Laboratory

The Mechanisms of Behavior Core offers the equipment, reagents, bench space, and expertise to answer questions related to the roles of genetics and hormones in relation to animal behavior.

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IU Indianapolis

Designated Service Core

Clinical Pharmacology Analytical Core (CPAC)

The Clinical Pharmacology Analytical core provides drug and metabolite concentrations from a variety of biological matrices such as (but not limited to): plasma, urine, CSF, and tissue using HPLC-MS/MS. Additional services include protein binding of drugs, formulation studies, drug stability, drug metabolism, and metabolite screening.

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Purdue University

Designated Service Core

Cryo-EM Facility

The Purdue Cryo-EM facility provides access to state-of-the-art instrumentation enabling users to collect data for high-resolution single particle reconstructions and tomographic studies of cells and larger complexes.

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IU Bloomington

Non-Designated Service Resource

Drosophila Genomics Resource Center

Resource center providing cDNAs, plasmids, Drosophila cell lines, transgenic cell line and authentication service.

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IU Bloomington

Designated Service Core

Electron Microscopy Center (IUB-EMC)

The IU Bloomington Electron Microscopy Center (IUB-EMC) provides equipment, services and expertise for biological and material science electron microscopy.

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IU Indianapolis

Non-Designated Service Resource

Electrophysiology Core

The Electrophysiology Core performs rodent brain slice electrophysiological recordings to measure brain cell function.

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Purdue University

Designated Service Core

Flow Cytometry and Cell Sorting Facility

The Purdue Flow Cytometry Core Facility provides instrumentation, data analysis software, training and technical expertise for flow cytometry analysis and cell sorting. Our capabilities also include the characterization of genome and transcriptomes using the Fluidigm C1 and 10X Genomics systems, in partnership with the Purdue Genomics Core Facility.

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IU Bloomington

Designated Service Core

Flow Cytometry Core Facility (FCCF)

The IU-B FCCF provides flow cytometry analysis, sorting and cell counting services, access to flow cytometry data analysis software, assistance with experimental design, and houses a mobile (on a cart) flow cytometry analyzer and a large particle sorter.

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IU Indianapolis

Designated Service Core

Flow Cytometry Resource Facility (FCRF)

The Flow Cytometry Resource Facility (FCRF) provides flow cytometric analysis and cell sorting services as well as flow cytometric image analysis.

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Notre Dame

Designated Service Core

Freimann Life Sciences Center (FLSC)

The Freimann Life Sciences Center is comprised of 2 state-of-the-art animal facilities equipped to house a wide variety of vertebrates. FLSC’s key goals are to support the University of Notre Dame’s teaching and research. The Center is fully accredited by the Association for Assessment and Accreditation of Laboratory Animal Care International.

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IU Indianapolis

Designated Service Core

Genome Editing Center

The Indiana University Genome Editing Center (IUGEC) is a shared resource whose mission is to provide Indiana University and external investigators access to state-of-the-art genome editing technologies by assisting with the generation of genetically modified mouse models and cell lines in a time- and cost-effective manner.

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Notre Dame

Designated Service Core

Genomics and Bioinformatics Core Facility (GBCF)

The Genomics & Bioinformatics Core Facility (GBCF) at the University of Notre Dame offers comprehensive services and support for state-of-the-art genomics experiments and bioinformatics analysis. This includes next generation Illumina sequencing, a variety of standard and specialty DNA and RNA library construction methods, consultation, and analysis support.

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Purdue University

Designated Service Core

Genomics Facility

The Purdue Genomics Core provides both next generation – Illumina NovaSeq and MiSeq – and Sanger sequencing with an additional method to provide entire plasmid sequences for less than $35 via a service called “WideSeq”.

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IU Indianapolis

Designated Service Core

HANDS In Autism Interdisciplinary Training & Resource Center

The HANDS (Helping Answer Needs by Developing Specialists) in Autism® Interdisciplinary Training & Resource Center is located within the Department of Psychiatry at the Indiana University School of Medicine. The HANDS team offers services including:
(1) recruitment,
(2) behavioral, educational, functional, and/or vocational assessment of individuals across a broad range of ages and functioning levels, and
(3) program evaluation efforts targeted to a range of …

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IU Indianapolis

Designated Service Core

Histology and Histomorphometry Core (HHC)

Histology and Histomorphetry Core (HHC) provides histological and histomorphometric services for basic science (non-clinical) research. Mineralized (plastic embedded), soft tissue (paraffin embedded), and cryopreserved specimens can be processed by the facility.

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Purdue University

Designated Service Core

Histology Research Laboratory (HRL)

The Histology Research Laboratory is a full service histology laboratory that provides general histology, immunohistochemistry, frozen sectioning, decalcified and undecalcified bone histology, and slide digitization services. Board certified veterinary pathologists are also available for consultation.

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IU Indianapolis

Non-Designated Service Resource

Human Vascular Imaging Core (HVIC)

The HVIC performs functional and anatomic vascular imaging measuremetns (flow-mediated dilation and carotid intima-media thickness).

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IU South Bend

Designated Service Core

Imaging and Flow Cytometry Core Facility

Standard confocal or multiphoton resources for imaging live or fixed samples and a 5 color flow cytometric analyzer are available. Data analysis software for each resource is also available on site.

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Purdue University

Designated Service Core

Imaging Facility

The Bioscience Imaging Facility, Purdue University, is a 24hr/7day access core facility specializing in confocal microscopy, multi-photon microscopy, pre-clinical molecular and nuclear imaging and computed tomography (mCT) with offline analysis workstations.

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IU Bloomington

Designated Service Core

Imaging Research Facility (IRF)

The IRF is a state-of-the-art neuroimaging facility that enables cutting-edge neuroscience research and training using non-invasive imaging methodologies, including both MRI and EEG.

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IU Indianapolis

Non-Designated Service Resource

Immunohistochemistry Research Lab (IHC Research Lab)

The Immunohistochemistry Research Lab specializes in assisting researchers with histologic and immunohistochemical labeling of cells or tissue sections as well as collaborations with surgical pathologists.

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IU Indianapolis

Designated Service Core

In Vivo Therapeutics Core (IVT)

The In Vivo Therapeutics Core (IVTC) supports the research and development of safe and more efficacious drug treatment. The IVTC provides cost-effective and comprehensive services including, but not limited to, on-site breeding facilities as well as a numerous in vivo pharmacology models to facilitate the development and testing of novel pharmacological & cellular therapies.

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IU Indianapolis

Designated Service Core

In-Vivo Imaging Core

The In-Vivo Imaging Core provides imaging services for clinical trials, observational, and preclinical studies. We also provide radiochemistry support for molecular imaging. Currently, the Imaging Core is equipped with state-of-the-art imaging systems, including 3T MRI scanners, PET-CT scanners, Bruker 9.4 T preclinical PET-MRI scanner, a Siemens Eclipse Medical Cyclotron, and Radiochemistry Facilities. Highly skilled faculty and staff are available to assist with research …

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IU Indianapolis

Designated Service Core

Indiana Center for Biological Microscopy (ICBM)

The ICBM provides researchers with access to laser-scanning confocal, 2-photon and epi-fluorescence microscopes (http://www.medicine.iupui.edu/ICBM/USING-THE-FACILITY).  Center personnel train individual researchers to use all imaging systems and provide expert help in the design, conduct and analysis of imaging studies.  As necessary, center personnel can also be hired to conduct microscopy studies for laboratories lacking the necessary expertise.

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IU Indianapolis

Designated Service Core

Infectious Diseases Laboratory (IDL)

The Infectious Diseases Laboratory (IDL) is skilled at performing clinical research studies including the evaluation of new molecular technologies for the diagnosis of a wide array of sexually transmitted pathogens, developing novel assays to meet the needs of individual research collaborators, and tailoring services to successfully meet study objectives. The laboratory has the capability to identify and type human papillomavirus (HPV) using molecular assays that can classify …

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Notre Dame

Designated Service Core

Integrated Imaging Facility (NDIIF)

The Notre Dame Integrated Imaging Facility (NDIIF) is a state-of-the-art research core that makes available to the Notre Dame science and engineering community, as well as external customers, an integrated suite of sophisticated microscopes and imaging stations. The NDIIF also provides resident professional staff (three Ph.D.-level imaging specialists and two technicians) to guide the non-expert users. 

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Notre Dame

Designated Service Core

Integrated Imaging Facility – Histology Core (NDHC)

The Notre Dame Histology Core (NDHC) provides a means to examine biological processes in mice, rats, frogs, zebra fish, fruit flies, sheep bone, and even human tissue by use of immunohistochemical techniques and pathology.

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IU Indianapolis

Non-Designated Service Resource

Investigational Agent Acquisition Program

Goal: The goal of the CTSI Investigational Agent Acquisition Program (IAAP) is to assist CTSI investigators seeking investigational agents for use in clinical trials.

Scope: The IAAP program will assist in acquiring drugs, neutraceuticals, biologics or other materials to be used in a Investigational New Drug Application or IND-exempt clinical trial.

Eligibility: Any faculty within the CTSI member institutions.

Overview: Moving bench …

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IU Indianapolis

Designated Service Core

Islet and Physiology Core

The Islet and Physiology Core of the Center for Diabetes and Metabolic Diseases provides investigators with the capability to obtain high quality rodent pancreatic islets for study.  The Core also provides services for islet transplantation and will assist investigators who wish to perform immunohistochemistry, immunofluorescence, and/or analysis of beta cell mass on whole pancreata from mouse and rat models. 

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IU Indianapolis

Designated Service Core

IUSM Center for Electron Microscopy (iCEM)

The Indiana University School of Medicine Electron Microscopy Center is a full service research laboratory providing both Transmission and Scanning Electron Microscopy. The service provided can apply both traditional methods and recent technical developments to suit the investigator’s needs.

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Notre Dame

Non-Designated Service Resource

Keck Center for Transgene Research (resources)

Unique research resources available for collaboration

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IU Indianapolis

Non-Designated Service Resource

Laboratory Animal Resource Center (LARC)

The Laboratory Animal Resource Center (LARC) contributes to and enhances the services and collaborative efforts of medical research at IU School of Medicine. In addition to the provision of basic husbandry for a wide variety of laboratory animal species, the veterinary staff and other highly experienced laboratory animal professionals of the IU School of Medicine LARC provide training, supplies, and specialized service support for medical research.

Mission

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IU Bloomington

Designated Service Core

Laboratory Animal Resources (LAR)

LAR provides housing, food, water, bedding, enrichment and medical care for animals housed in LAR animal facilities to be used for research. Research is overseen by an Institutional Animal Care and Use Committee (IACUC) and the Institutional Official and is accredited by AAALAC International and their three primary standards (The Guide for the Care and Use of Laboratory Animals, Guide for the Care and Use of Agricultural Animals in Research and Teaching, and the European …

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IU Bloomington

Designated Service Core

Laboratory for Biological Mass Spectrometry (LBMS)

The LBMS uses mass spectrometry to characterize proteins as well as other biologically-derived molecules. It specializes in the characterization of protein post-translational modifications, including glycosylation, phosphorylation, acetylation and persulfidation (S-sulfhydration). We also have an emphasis on identification of protein-interactions (including determination of protein-protein crosslinks) and quantitative comparisons of complex samples.

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Purdue University

Designated Service Core

Life Science Microscopy Facility

The Life Science Microscopy Facility (LSMF) is an electron microscopy core with both service and individual use options.

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IU Bloomington

Designated Service Core

Light Microscopy Imaging Center (LMIC)

The LMIC provides access and training for confocal and super-resolution light microscopy systems with support for experimental design and data visualization.

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IU Bloomington

Designated Service Core

Macromolecular Crystallography Facility Integrated with the Crystallization Automation Facility (MCF/CAF)

The Macromolecular X-ray Crystallography Facility provides all resources for Crystal Screening and Optimization, Data Collection and Structure Determination of macromolecules.

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Notre Dame

Non-Designated Service Resource

Magnetic Resonance Research Center

The Magnetic Resonance Research Center (MRRC) supports research in chemistry, biochemistry, molecular biology, engineering and related fields. The MRRC operates six solution-state NMR spectrometers (400 to 800 MHz), a solid-state 300 MHz NMR instrument, and an X-band EPR spectrometer. Most instruments are equipped with sample changers for increased sample throughput. See the MRRC website for more information.

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Notre Dame

Designated Service Core

Mass Spectrometry and Proteomics Facility

Analysis of large and small molecules using several ionization methods, low or high resolution, hyphenated techniques, proteomics, and metabolomics.

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IU Bloomington

Designated Service Core

Mass Spectrometry Facility

The Indiana University Mass Spectrometry Facility (MSF) provides qualitative and quantitative small molecule mass spectrometry data. It also confirms chemical formulae of novel compounds by accurate mass spectrometry.

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Purdue University

Designated Service Core

Metabolite Profiling Facility (MPF)

The Metabolite Profiling Facility (MPF) provides both qualitative (comparative analysis) and quantitative (absolute concentrations) metabolite chemical analysis in complex biological systems.

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IU Bloomington

Non-Designated Service Resource

METACyt Biochemical Analysis Center

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Notre Dame

Non-Designated Service Resource

Molecular Structure Facility

The Molecular Structure Facility at the University of Notre Dame provides for X-Ray structural studies of small (ca. 2kDa) molecules. The Facility has the capability to examine a wide range of molecules from “light atom” biologically relevant to metal-complexed compounds which can be readily analyzed using non-destructive techniques.

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IU Indianapolis

Designated Service Core

Multiplex Analysis Core (MAC)

The Multiplex Analysis Core (MAC) offers microplate-based immunoassay systems that can perform multiplex analysis of multiple different analytes in a single sample. The MAC uses a Bio-Plex 200 Multiplex System with High Throughput Fluidics based on Luminex technology.

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IU Bloomington

Designated Service Core

NMR Facility

The NMR Facility offers solution NMR spectroscopy services for small and large molecules.

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IU Indianapolis

Non-Designated Service Resource

Ossabaw Swine Resource

The overall goal of the core is to provide Ossabaw miniature swine, technical resources, and tissues for preclinical translational research. Please see also our website for additional description, research articles, etc. We have the only research and large-scale breeding colony of Ossabaw swine in the world that is certified to have a gene mutation, the metabolic syndrome, and heart disease. The striking similarities between swine and human biochemistry, physiology, and …

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IU Bloomington

Non-Designated Service Resource

Oxidative Stress and Environmental Analysis Core

The Oxidative Stress Environmental Analysis Core laboratory has established a number of measurements for assessing oxidative stress and damage in a variety of biological samples with excellent accuracy and reproducibly using state of the art LC-MSMS, GC, and PCR equipment.

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Purdue University

Non-Designated Service Resource

Pharmaceutical Manufacturing Core Facility

Pharmaceutical Manufacturing Core Facility provides support and capabilities for a wide range of research in pharmaceutical development and manufacturing. Technical support for the Facility is provided by the faculty of Industrial and Physical Pharmacy who have extensive pharmaceutical manufacturing experience in both industrial and academic environments.

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IU Bloomington

Designated Service Core

Physical and Biochemistry Instrumentation Facility (PBIF)

The PBIF provides resources to characterize particle properties as well as macromolecular interactions.

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Purdue University

Designated Service Core

Pre-Clinical Research Laboratory (PCL)

The Pre-Clinical Research Laboratory (PCL) helps researchers conduct pre-clinical animal research by providing research expertise, technical support, surgical experience, and surgical facilities and equipment. The PCL is a multidisciplinary laboratory where researchers conduct advanced clinical and applied research using induced animal models ranging from rodents to pigs and sheep

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IU Indianapolis

Non-Designated Service Resource

Preclinical Innovation Think Tanks

Indiana CTSI Think Tanks are an opportunity for researchers at any of the Indiana CTSI campuses of Indiana University (IU), Purdue University and the University of Notre Dame to get help advancing their discoveries to the market. The Drug and Device Think Tanks each serve as a one-stop shop where investigators can receive guidance from a pool of advisors with a wide range of scientific, technical, clinical, business, and regulatory expertise.

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IU Indianapolis

Designated Service Core

Preclinical Modeling and Therapeutics Core (PMTC)

The Preclinical Modeling and Therapeutics Core (PMTC) facilitates the development of pharmacological and cellular therapies for cancer. It provides advanced resources essential for the preclinical validation of novel drug targets and biomarkers of cancer. The PMTC provides expertise in:
• Cellular response technologies
• Breeding of specialized mouse strains
• Tumor modeling
• In vivo therapeutics efficacy & safety testing
• Hematopoietic …

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Purdue University

Designated Service Core

Proteomics Facility

The Purdue Proteomics Facility provides chromatography, mass spectrometry and bioinformatic resources for the research communities on campus and beyond for protein characterization. These services include protein identification, relative and absolute quantitation, mapping post-translational modifications, and discovering new protein complexes and protein-protein interactions from a wide variety of sample types such as gel bands, cell or tissue lysates, and plasma or serum. …

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Purdue University

Designated Service Core

Purdue MRI Facility

The Purdue MRI Facility houses two 3T full body MRI systems and one 7T small bore (animal) MRI system that are available for research involving MRI, MR spectroscopy, and other MR applications.

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IU Indianapolis

Designated Service Core

Regenstrief Data Services

Services RDS offerings include, but are not limited to:

• Feasibility
• DIY: i2b2
• Cohorts
• Recruitment Lists
• Registries
• Patient Lists
• Geocoding
• Phenotyping
• Deidentification
• EHR Integration/Innovation
• Application Development
• Application Prototypes
• Natural Language Processing (NLP)
• Data Linkage
• Machine Learning Models …

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IU Indianapolis

Non-Designated Service Resource

Research Jam

Research Jam is an interdisciplinary team of healthcare, research, and design professionals. The team uses human-centered design research to collaborate with doctors, patients, and community members in an effort to ensure that health research, interventions, and communications are more relevant to the community they aim to serve. By engaging stakeholders in a co-design process, they are able to assist clients with recruitment strategies, study retention, and protocol …

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IU Indianapolis

Non-Designated Service Resource

SNRI Biomarker Core

The nanoString nCounter Analysis system utilizes a novel fluorescent color-coded molecular barcode technology coupled with single molecule imaging to perform digital nucleic acid (RNA and DNA) counting. This technology enables investigators to profile hundreds of targets simultaneously, up to 800 mRNA or miRNA targets in a single reaction for many kits.

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IU Indianapolis

Designated Service Core

3D Bioprinting Core (3DBPC)

We provide 3D bioprinting services with the Regenova Bio 3D Printer to generate tissue models (e.g., bone and liver) and we provide FABRICA bioreactor platforms to properly perfuse bioprinted tissue models with blood or cell culture media.

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IU Indianapolis

Designated Service Core

Tissue Procurement and Distribution Core

The Tissue Core strives to provide the best quality research specimens for basic, clinical and translational studies. Specimens with confirmed histology and diagnosis are available from surgical or other clinical procedures within 90 minutes post-excision/extraction from a large variety of cancers and other diseases.

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Purdue University

Designated Service Core

Transgenic and Genome Editing Facility (TGEF)

Offering transgenic and CRISPR-mediated targeted gene editing in mice and rats; gene-targeting in mouse embryonic stem cells (ES) cells; embryo and sperm cryopreservation; in vitro fertilization; rederivation for importation or clean-up of infected lines. Also offering assistance with project design and mouse/rat breeding colony maintenance.

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IU Indianapolis

Designated Service Core

Translation Core

The Translation Core provides services that facilitate the conduct of research involving human subjects, including supplying low-cost, high-quality analyte measurements for a variety of hormones, cytokines, lipids and other analytes. Translation Core human studies services include phenotyping (i.e. GTT, clamp studies, tracer studies), and access to a biobank of human tissues and serum.

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Purdue University

Designated Service Core

Translational Pharmacology Facility

The PTP Core offers automated blood monitoring in rodents and large animals utilizing stress free sampling through CulexTM technology. We perform a host of services from early lead identification PK and PD assessment through product testing of human formulations in pigs and minipigs, including preclinical formulation development, biodistribution studies, metabolomics analysis, and in vivo toxicological evaluation.

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IU Indianapolis

Non-Designated Service Resource

Translational Research Core (TRC)

The Translational Research Core specializes in assisting researchers with the identification/development and analysis of laboratory correlates in translational research.

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IU Indianapolis

Non-Designated Service Resource

Vector Production Facility (IUVPF)

IUVPF produces retroviral and lentiviral vectors for both pre-clinical and FDA Phase I/II human gene therapy clinical trials.

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Purdue University

Non-Designated Service Resource

Veterinary Clinical Trials (VCT)

The Veterinary Clinical Trials Support Service (VCT) facilitates veterinary clinical trials and provides expertise and technical support for translational clinical investigations using animal models of spontaneous, naturally-occurring diseases in client-owned animals and for trials leading to novel drugs or devices.

|2021-09-20T07:53:05-04:00September 20th, 2021|Comments Off on Service Cores

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