Submission
| Title: | Cognitive Deficits in Acute Opioid Withdrawal: A Review |
| Presenter: | Faizan Khan |
| Institution: | Indiana University Bloomington |
| Authors: | Faizan Khan 1; RA Chambers, MD 2,3; Brett Montieth, MD, MS 3
1 CTSI Undergraduate Summer Research Intern, 2 Professor of Psychiatry, IU School of Medicine, Indianapolis, IN, 3 Laboratory for Translational Neuroscience of Dual Diagnosis & Development |
Abstract
| Background/Significance/Rationale: | Opioid addiction can be characterized by a cycle of use, withdrawal, and relapse. Cognitive deficits during opioid use, maintenance, and long-term abstinence are consistently found in studies. Due to the debilitating withdrawal experience, it is necessary to define the cognitive effects there are to pave the way to a solution. |
| Methods: | A literature review using Google Scholar, PubMed, and a reference list search was conducted for studies on the cognitive effects of opioid withdrawal. |
| Results/Findings: | Cognitive deficits were found during opioid withdrawal. Little research was found; less using human subjects. |
| Conclusions/Discussion: | This lack of literature calls for intentional future research. Due to the many causes of cognitive decline and its intersection with other mental illness, lifestyle choices, and withdrawal effects, it is important to isolate opioid withdrawal in order discern its real impact on cognition. |
| Translational/Human Health Impact: | From this review of this topic, it has become clear that not enough intentional research has been done. Researchers need to dive deeper into cognition and opioid withdrawal to identify the extent of the impairment and the best away to address it. |
