The Indiana CTSI Translational Informatics Program offers a range of tools and technologies to help investigators access data, perform queries, and share information.

The following is a (growing) list of tools available to investigators through this site as well as externally.

Prospective Patient Search and Cohort Discovery

  1. i2b2:  i2b2 is an open-source web-based tool provided by the Indiana CTSI and Regenstrief Institute to investigators for de-identified clinical data queries with minimal risk to patient privacy.  Additional resources for discovering and analyzing patient data are provided by the Regenstrief Data Core

Collaboration and File Sharing

  1. Box (Indiana University): Box is a no-cost cloud storage and collaboration environment available to students, faculty, and staff at Indiana University for sharing documents securely. For more information, see the FAQ.
  2. Box and other tools at Notre Dame available through the Shared File Space site.
  3. FileLocker at Purdue University PURR and FileLocker Purdue University
  4. Research Data Sharing: See REDCap below.
  5. SciValReSEARCH Connect: This program enables researchers to find scientists who are conducting research in similar areas, or have useful complementary expertise.

Data Capture & Management

  1. REDCap(Research Electronic Data Capture): REDCap is an easy-to-use database management tool used to capture, use, and share research data. It is also a tool to create, conduct, and manage online surveys.


  1. Thomson Reuters Services:  Thomson Reuters Services include access to MetaCore™, a pathway analysis suite and MetaDrug™, small molecule analysis tool. Access is provided to investigators at Indiana, Purdue, and Notre Dame Universities at a significantly reduced rate.
  2. QIAGEN Ingenuity Pathway Analysis:  A powerful analysis and search tool that uncovers the significance of ‘omics data and identifies new targets or candidate biomarkers within.

Biomedical Databases

  1. GOBIOM Biomarkers Database:  GOBIOM is a comprehensive collection of all clinically evaluated biomarkers associated with different therapeutic areas reported in global clinical trials and preclinical markers in patients. Access is free investigators at IU, Purdue and Notre Dame and is supported by the Indiana CTSI Bioinformatics CORE and Indiana Institute for Personalized Medicine.

Search & Discovery

  1. Direct2Experts:  Direct2Experts is a search tool which provides easy online access to profile information on faculty researchers across the country. The Indiana CTSI is one of 29 institutions in the CTSA Consortium participating in the program.
  2. MedLine Plus:  MedlinePlus has extensive information from the National Institutes of Health and other trusted sources on over 975 diseases and conditions. There are directories, a medical encyclopedia and a medical dictionary, health information in Spanish, extensive information on prescription and nonprescription drugs, health information from the media, and links to thousands of clinical trials. MedlinePlus is updated daily.
  3. Quertle Qexplorer™:  Qexplorer™ is an innovative tool for and investigating the biomedical literature. It is geared to active life science professionals, including researchers and health care providers, and is designed to save them considerable time and effort in finding the literature they need. Qexplorer™ simultaneously searches multiple sources of life science literature, including the PubMed, NIH Grant Applications and TOXLINE.

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