Translational Research Development Program
This page lists all Indiana CTSI funding opportunities currently accepting applications. Clicking on the Request For Application (RFA) title will provide you with further details.
The “Click here to start a submission” link at the bottom of each RFA will take you to the Indiana CTSI grants system (which requires login) and allows you to start the application process.
The “Return to your submission” link at the bottom of each RFA will take you to the Indiana CTSI grants system (which requires login) and allows you to return to an application that you have already started (once your account has been created if you are a new user).
The Indiana CTSI also has several resources to assist you as you plan your RFA submission:
ALL OPEN RFAs
Global Health Reciprocal Innovation Planning Award
The goal of this request for applications (RFA) is to facilitate the planning and designing of reciprocal innovation projects focusing on one of the identified priority areas. Activities in this RFA will be implemented through principal investigators from Indiana CTSI institutions (IU, Purdue, and Notre Dame) and collaborative partnerships between Indiana state health partners, nonprofit organizations, educational institutions, health systems, government agencies, and partners from low- or middle-income countries (LMIC). The planning efforts must demonstrate an understanding of shared health challenges in underserved communities in Indiana and LMIC partner sites, as well as a commitment to the development of new programs or partnerships that will result in the development and demonstration of reciprocal innovation projects.
This award is designed to provide preliminary support for investigators to establish partnerships, develop project teams, identify promising health innovations for demonstration, develop evidence to support the demonstration of a reciprocal innovation in Indiana or at an LMIC partner site, conduct training to prepare for a reciprocal innovation demonstration project, and other activities needed to prepare competitive demonstration grant applications for reciprocal innovation.
Applicants may request up to $10,000 for a period of 1 year.
University of Notre Dame Matching Funds: University of Notre Dame Eck Institute for Global Health will provide up to $10,000 matching funds for successful Notre Dame faculty and affiliated members of the Eck Institute for Global Health. Researchers who meet this criterion may submit a budget inclusive of this additional funding. For questions on eligibility, please contact Nydia Morales-Soto (nsoto@nd.edu).
Contact Information: Rish Chauhan O’Brien rchauhan@iu.edu
Files for Investigators
- Webcamp users guide
- Global Health Planning Guidelines
- Global Health Application
- Video: What is Reciprocal Innovation?
- Video: What is the Purpose of the Reciprocal Innovation Planning Grant?
- Video: What is the Selection Committee Looking for in the Reciprocal Innovation Planning Grant Applications?
Click here to start a submission
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Center for Diabetes & Metabolic Diseases Pilot & Feasibility Grant
SUBMISSION DEADLINE: March 27, 2023 (online)
A primary research-related activity of the Center for Diabetes and Metabolic Diseases (CDMD)’s Pilot and Feasibility (P&F) program is to foster the development of new diabetes-related investigators and provide seed-support for innovative, high-risk projects.
The CDMD P&F program has three different grant mechanisms:
- Parent P&F Grants: This mechanism invites applications directed towards basic biomedical, clinical, and/or translational research questions on cellular and molecular metabolism related to diabetes/obesity/metabolic syndrome, clinical and outcomes research in diabetes and obesity, complications of diabetes and obesity, islet function and survival, and nutrition and physiology of diabetes and obesity.
- Alzheimer’s-Focused P&F Grants : This mechanism invites applications focused on diabetes and metabolic disease aspects of Alzheimer’s disease and its related dementias (AD/ADRD)–frontotemporal dementia, Lewy body dementia, vascular cognitive impairment with dementia, and multiple etiology dementias.
- Physician-Scientist P&F Grants: This mechanism invites applications from exceptional emerging physician-scientists holding an MD (or equivalent) or MD/PhD with a patient-oriented diabetes and/or obesity-related clinical research project, who are early in their clinical research careers and show great promise to develop into future independent investigators.
The program is directed at:
Awards are up to $50,000 for one year
Contact Information: Jeffrey S. Elmendorf, PhD jelmendo@iupui.edu
Files for Investigators
Click here to start a submission
Click here to return to your submission
Global Health Reciprocal Innovation Demonstration Grants
FULL SUBMISSION DEADLINE: March 30, 2023 online via link provided by Rish O’Brien
For this funding announcement, the Indiana CTSI encourages applications from individuals with full-time, regular faculty appointments and postdoctoral research associates. Postdoctoral applicants must include their mentor on the investigator team as well as their letter of support in the submission package. This award is designed to support research and demonstrate innovations with a high potential to alleviate the health burden of one of the priority areas. Projects should result in high impact solutions that provide reciprocal benefit to the communities Indiana CTSI institutions serve either at home or abroad, as well as a plan to sustain and expand these efforts into either the partner country or US/Indiana after the end of support from this RFA.
Awards are up to $50,000 for a period of two years.
Submission of a letter of intent is required in order to receive approval for the submission of a full proposal. The letter of intent should address the following elements (see draft linked below):
- Scope and specific aims of the research project
- Project team including US and international partners and collaborators
- The reciprocal nature of the research project
Contact Information: Rish Chauhan O’Brien rchauhan@iu.edu
Files for Investigators
- Global Health Reciprocal Innovation Demonstration Guidelines
- Global Health Reciprocal Innovation Demonstration Application
- Global Health Reciprocal Innovation Demonstration Letter of Intent Template
Translational Population Health Research Award
The goal of the Indiana University School of Public Health - Bloomington is to provide a more holistic model for the field of population health so that the individual, social, environmental and policy factors that support optimal health and wellness have a viable framework from which to approach the current human health conditions. Applications may focus on any aspect of population health but ultimately lead to the improvement of human health outcomes. These applications require a partnership between an IUB faculty member and a public health liaison and / or collaborator at another Indiana CTSI partner institution. PIs are strongly encouraged to include other Indiana CTSI affiliate faculty but this not a requirement. Collaborations need not be established prior to submission but should demonstrate the equal contribution of each team member and how synergism will be achieved.
Applications are expected to have a maximum requested amount of $50,000/year for two years for a total of $100,000.
Contact Information: Joel Ybe jybe@indiana.edu
Files for Investigators
Click here to start a submission
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Indiana CTSI (IUSM) Core Equipment Grant
The Indiana CTSI is seeking proposals from CTSI Designated IU School of Medicine Cores requesting support for the purchase of equipment that will enhance the research environment and contribute to the research mission of the School and the CTSI.
Proposals requesting equipment costing between $5,000 - $100,000 will be accepted. Proposals for equipment costing more than $100,000 will be entertained if matching funds to cover the balance are identified.
Eligibility:
- Only Cores based within the IU School of Medicine are eligible.
- Only CTSI Designated Cores are eligible.
Contact Information:Translational Research Development trnsldev@iu.edu
Files for Investigators
Click here to start a submission
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Pilot Funding for Research Use of Core Facilities
The Indiana CTSI Pilot Funding program is intended to promote the use of technologies and expertise afforded by the Indiana CTSI Core Facilities available at all partner institutions. Successful proposals will demonstrate outstanding scientific merit that can be linked to generating extramural funding or novel intellectual property (IP). Success of the program will be viewed, in part, by the fostering of new funded grants or providing significant contributions to grant renewals. Therefore, proposals will be judged with equal measure on scientific merit and the likelihood of generating new IP or extramural grant support.
Funding is for a maximum requested amount of $10,000; projects are typically two years in duration.
Funding is for utilization of designated Indiana CTSI core facilities only. Information describing each core is available at https://indianactsi.org/servicecores/
A letter from each Core Director where service is required and must be included in the application.
Contact Information:Translational Research Development Program trnsldev@iu.edu
Files for Investigators
Click here to start a submission
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IUSCCC “Near-Miss” NIH R01 Initiative
The IU Simon Comprehensive Cancer Center (IUSCCC) is providing an opportunity to fund cancer focused PI-directed applications to the National Institutes of Health that have been reviewed once and missed the NIH pay line and have a high potential for obtaining external funding. The goal is to increase the cancer focused NIH funding base in the IUSCCC. Non-NCI targeted applications should have significant cancer relevance.
Investigators wishing to apply to this funding mechanism must first submit a draft cover letter (letter of intent) for approval by the IUSCCC Executive Committee before working with a Coordinator to submit a full application. Once approved, the link for submitting the online application will be sent.
Maximum allowable amount for R01, R42 and R44 grants is $50K with P01 and SPORE funding amounts evaluated on a case-by-case basis. .
Contact for Letter of Intent and Questions: Kaitlin Condron kcondron@iu.edu or Crystal Baker crybanks@iupui.edu
Files for Investigators
Stark Neurosciences Pre-Clinical Neuroimaging Pilot Grant
The goal of the Pre-Clinical Neuroimaging Research Pilot Study program is to facilitate the generation of new knowledge in the neurosciences through the development of funded research programs. This mechanism will provide seed-support up to $10,000 for innovative, high-risk animal imaging projects using the Bruker BioSpec 9.4T PET-MRI scanner using the IIBIS In-Vivo Imaging Core.
Applicants (the contact PI) from one of the following three categories are eligible to apply:
Award amount is up to $10,000 for one year.
Contact Information: Yu-Chien Wu, Scientific Director for the Roberts Translational Imaging Facility yucwu@iu.edu
Files for Investigators
Click here to start a submission
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Biomedical Research Grant (BRG)
The Biomedical Research Grant program is open to all IU School of Medicine (IUSM) faculty that are full-time, regardless of tenure status, having an appointment of Assistant/Associate/Full Professor and Assistant/Associate/Full Scientist. In general, two categories of research projects will benefit from this program: 1) research projects of investigators new to IUSM who do not yet have extramural funding and who need support to acquire the preliminary data necessary to compete for extramural funding; 2) research projects of established IUSM investigators who are between funding periods from extramural sources.
Applications are considered small grants and should have a maximum requested amount of $50,000 and be limited to one (1) year duration
Contact Information: 317-278-2822 trnsldev@iu.edu
Files for Investigators
Click here to start a submission
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Research Enhancement Grant (REG)
The IUSM Research Enhancement Program is designed to stimulate research productivity at the statewide Centers for Medical Education (regional campuses) including the Bloomington Medical Sciences Program. This does not include the IUPUI campus. All full-time Center/Medical Sciences faculty, regardless of tenure status, having an appointment of Assistant/Associate/Full Professor or Assistant/Associate/Full Scientist at time of submission, are eligible to apply for a Research Enhancement Grant. Primary appointment must be in the School of Medicine. Faculty in visiting ranks are not eligible for funding through this mechanism.
Applications are considered small grants and should have a maximum requested amount of $50,000 and be limited to one (1) year duration
Contact Information: 317-278-2822 trnsldev@iu.edu
Files for Investigators
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Maternal and Pediatric Precision In Therapeutics (MPRINT) Hub Data and Modeling Knowledge & Research Coordination Center (KRCC) P30 Opportunity Fund Awards
The MPRINT Hub serves as a national resource for expertise in maternal and pediatric therapeutics to conduct and foster therapeutics-focused research in obstetrics, lactation, and pediatrics while enhancing inclusion of people with disabilities. More information about the MPRINT Hub can be found here
This opportunity coordinates and supports the operations of the entire MPRINT Hub, providing a knowledge base that will aggregate and identify knowledge deficits in the principles of maternal and pediatric therapeutics including pharmacokinetics, pharmacodynamics, genetics, proteomics, and metabolomics that inform drug development and regulatory science.
Funding for one year for a combination of clinical fellow / postdoctoral fellow awards up to $25,000 and faculty awards up to $150,000 (total costs) for a total award amount in the range of $500,000.
Contact Information: info@mprint.org
Files for Investigators
Indiana Alzheimer’s Disease Research Center (IADRC) Developmental Project Award
FULL SUBMISSION DEADLINE: April 17, 2023 @ 5:00 PM
This funding mechanism is intended to support investigators in developing preliminary data sufficient to provide a basis for an application for independent research support in Alzheimer’s disease and related dementias (AD/ADRD). Proposals should describe innovative basic, clinical, behavioral, translational, epidemiologic, caregiving, or educational research likely to advance the understanding of the basic and clinical underpinnings of Alzheimer’s disease and related cognitive disorders.
The IADRC Developmental Project Program will award three projects for $50,000 (for a total of up to $100,000) for up to two years.
Contact Information: Sarah Van Heiden svanheid@iu.edu
Files for Investigators
Community Health Partnerships Trailblazer Award
Indiana CTSI Community Health Partnerships is soliciting proposals for collaborative, community-engaged research projects focused on topics that have potential to improve health equity in Indiana. Examples of work we are interested in funding include substance misuse, tobacco use, obesity prevention, infant mortality, cardiovascular disease and diabetes, as well as disparities in rural areas. This RFA encourages and prioritizes projects that have outlined a sustainability plan using existing Indiana CTSI infrastructure (i.e., Connections IN Health, Monon Collaborative) and/or connections to statewide health initiatives.
Eligible projects will propose to either: (1) implement research that has the potential to identify or reduce health inequities; or (2) evaluate an existing health-related program that has the potential to improve health equity. Projects that propose to achieve their objectives by changing (or demonstrating the potential to change) policy, systems, and/or the environment are encouraged.
There must be both 1) a university lead and 2) a community lead for the project, both partners must currently work in an Indiana-based institution or organization.
Funding may be requested up to $25,000 over two years
Contact Information: Community Health Partnerships chep@iupui.edu
Files for Investigators
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Community Health Partnerships (CHeP) Trailblazer Planning Grant
The Indiana CTSI Community Health Partnerships is soliciting proposals for the development of community-university partnerships to improve health, examine social determinants of health, or enhance health equity to result in future collaborative research proposals. The award can be used to establish new partnerships or to strengthen/expand existing community-university partnerships to solve critical health problems affecting Indiana residents. This award will not fund research pilot projects; instead, it will fund activities that help develop partnerships between organizations that have potential to later engage in joint research projects to address health, health equity or social determinants of health. The expected outcome of this award is the development of a future research proposal for opportunities such as the Community Health Partnerships Trailblazer Award. Examples of partnership development activities we are interested in funding include meetings, conferences, travel expenses, and quality improvement assessments.
Awards will be up to $5,000 for one year to allow for partnership growth and collaborative grant proposal development.
Contact Information: chep@iupui.edu
Files for Investigators
Click here to start a submission
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IUSCCC Early Career Investigator Award
SUBMISSION DEADLINE: May 1, 2023
The IU Simon Comprehensive Cancer Center (IUSCCC) and the IUSCCC Junior Faculty Special Interest Group (SIG) are inviting proposals for pilot/feasibility research projects in any area of basic, translational, or clinical cancer research (diagnostics, therapeutics), and population science research (prevention, survivorship, quality of life, epidemiology) that would serve to advance the applicants’ career goals.
The principal investigator must be an Associate level member in an IUSCCC Research Program or an Affiliate IUSCCC member at the level of: Assistant Professor, Research Assistant Professor, Assistant Scientist, Associate Research Professor, or Research Scientist. Current IUSCCC trainee members are also eligible, provided they will have a full faculty appointment and Associate or Affiliate level IUSCCC membership at the time of application submission.
Investigators wishing to apply to this funding mechanism must first submit a Letter of Intent for approval to Steven Verhagen stverhag@iupui.edu Once approved, the link for submitting the online application will be sent.
The duration of this pilot funding is one year, and the budget should not exceed $50,000.
Contact for Letter of Intent and Questions: Steven Verhagen stverhag@iupui.edu
Files for Investigators
DHART SPORE Developmental Research Program (DRP) & Career Enhancement Program (CEP) Awards
The IU School of Medicine Department of Pediatrics is a member of the multi-institutional Developmental and Hyperactive Ras Tumor (DHART) SPORE program. The goal of the SPORE program is to improve the diagnosis and management of tumors arising in persons with neurofibromatosis type 1 (NF1) and other inherited “Rasopathy” syndromes through basic, translational, and clinical research.
IU investigators who lead the DHART SPORE program conduct their research within the Herman B Wells Center for Pediatric Research, a national leader in childhood disease research. To learn more about the DHART SPORE program, including its cores, ongoing projects and overall approach, visit dhartspore.org.
Two funding opportunities are available via this program: the Developmental Research Program (DRP) and the Career Enhancement Program (CEP).
Awards: Funding is available for one or two DRP projects at $50,000 - $75,000 AND two to three CEP projects at $50,000 - $75,000. Awards will be for a 12-month period.
Eligibility: Proposals are accepted from clinical or basic science investigators at any DHART SPORE institution as well as from other academic institutions. See guidelines for additional eligibility criteria
Contact Information: Kevin Shannon / Jaishiri Blakeley kevin.shannon@ucsf.edu jblakel3@jhmi.edu
Files for Investigators
- Webcamp users guide
- DHART SPORE Application
- DHART SPORE Career Enhancement Program (CEP) Guidelines
- DHART SPORE Developmental Research Program (DRP) Guidelines
Click here to start a submission
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Alzheimer’s Disease Pre-clinical Translational Science Grant
Description: This funding opportunity announcement invites applications from all CTSI investigators with a full-time academic appointment for up to $50,000 to support innovative research work that is in scope and aligned with the research activities of the IUSM-Purdue TREAT-AD Center. These include (but are not limited to):
- Bioinformatic analyses and drug target hypothesis generation within neuroinflammatory pathways
- Target validation studies for proposed drug targets
- Innovative chemical biology and cellular pharmacology studies for proposed targets that provide insights to disease initiation and progression
- Structural biology or biophysical studies on proteins proposed as drug targets
- De-novo drug design approaches for proposed targets Novel PET ligands and supporting CSF biomarkers for preclinical studies and clinical trials, etc.
Contact Information: Alan D. Palkowitz, Director for the IUSM-Purdue TREAT-AD Center apalkow@iu.edu
Files for Investigators
- Webcamp users guide
- Alzheimer’s Disease Pre-clinical APPLICATION
- Alzheimer’s Disease Pre-clinical GUIDELINES
Click here to start a submission
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