Translational Research Development Program
This page lists all Indiana CTSI funding opportunities currently accepting applications. Clicking on the Request For Application (RFA) title will provide you with further details.
The “Click here to start a submission” link at the bottom of each RFA will take you to the Indiana CTSI grants system (which requires login) and allows you to start the application process.
The “Return to your submission” link at the bottom of each RFA will take you to the Indiana CTSI grants system (which requires login) and allows you to return to an application that you have already started (once your account has been created if you are a new user).
The Indiana CTSI also has several resources to assist you as you plan your RFA submission:
ALL OPEN RFAs
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IUSM Eligible |
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Collaboration focused |
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IU / IUB / IUI Eligible |
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Education focused |
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Purdue Eligible |
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Innovation focused |
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Notre Dame Eligible |
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Institutional resource award |
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Non-CTSI Eligible |
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IU Simon Comphrehensive Cancer Center |
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Indiana Biomedical Research Institute |
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Click the buttons above to open the all the corresponding RFAs
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All Open RFAs
Research Project Development Teams (PDTs)
RESEARCH PROJECT DEVELOPMENT TEAMS (PDTS): Rolling submission
$ / IUSM / IU / PU / ND
Research Project Development Teams (PDTs) are groups of experienced senior faculty located on each of the Indiana CTSI campuses who will connect you with resources, collaboration opportunities, and small (typically up to $15,000) awards for preliminary or additional data. Each PDT is designed around a common research theme.
There are biostatisticians and regulatory experts on each team, and add other experts are added as needed when you meet with the team to discuss your application. You will have access to the expertise and knowledge you need all in one place.
The PDT application process is contingent on the stage of the project. Please read the descriptions below and use the application link for the stage that is most appropriate for your proposal.
- PROJECT REFINEMENT: seeking first grant submission and additional resources, e.g. pilot funding, collaborators, regulatory support, statistical support
- PROJECT REVISION: seeking assistance after first round grant submission and possible resources for a resubmission
Contact: Tammy Sajdyk tsajdyk@iu.edu
Click here to start a project refinement submission
Click here to start a project revision submission Click here to return to your submission
Cancer Center “Near-Miss” NIH R01 Initiative
NOTICE OF INTENT (NOI) DEADLINE: Rolling submission to Crystal Banks crybanks@iu.edu or Kaitlin Evans kcondron@iu.edu
FULL SUBMISSION DEADLINE: Rolling submission after NOI
$$ / CC
The IU Simon Comprehensive Cancer Center is providing an opportunity to fund cancer focused PI-directed applications to the National Institutes of Health that have been reviewed once and missed the NIH pay line and have a high potential for obtaining external funding. The goal is to increase the cancer focused NIH funding base. Non-NCI targeted applications should have significant cancer relevance. Investigators wishing to apply to this funding mechanism must first submit their project to the IU External Resubmission Grant opportunity for funding consideration. If the project is not funded at the University level, an investigator can submit the project to the Cancer Center’s Near-Miss initiative for funding consideration. Investigators wishing to apply to this funding mechanism must first submit a draft cover letter (letter of intent) for approval by the Cancer Center’s Executive Committee before working with a Coordinator to submit a full application. Once approved, the link for submitting the online application will be sent. Maximum allowable amount for R01, R42 and R44 grants is $50K with P01 and SPORE funding amounts evaluated on a case-by-case basis.
Contact for Notice of Intent and Questions:
Kaitlin Evans
kcondron@iu.edu or Crystal Banks
crybanks@iu.edu
Files for Investigators
Click here to return to your submission
Cancer Center Community-Academic Collaborative Program Award
$ / C / CC
LETTER OF INTENT (LOI) SUBMISSION DEADLINE: Rolling submission via email to crybanks@iu.edu
FULL SUBMISSION DEADLINE: Rolling submission Investigators wishing to apply to this funding mechanism must first submit a Letter of Intent for approval to crybanks@iu.edu Once approved, the link for submitting the online application will be sent.
IU Simon Comprehensive Cancer Center, Office of Community Outreach and Engagement is inviting collaborative proposals for implementing evidence-based cancer related programs within the community. Proposals should focus on the cancer burden in Indiana. The program should have an evaluation component and priority will be given to one of the major cancer burdens in Indiana including lung, breast, colon, pancreas, prostate and cervical. We are particularly interested in programs that can lower risk behaviors related to cancers which drive cancer incidence and morbidity. Of particular interest are community-led programs that will increase our reach or understanding of the underserved populations in Indiana. The project must be co-led by an CC faculty member and community advocate or partner.
The duration of this funding is one year, and the budget should not exceed $15,000.
Contact: Crystal Baker crybanks@iu.edu
Files for Investigators
- Webcamp users guide
- CC Community-Academic Collaborative Program Application
- CC Community-Academic Collaborative Program Guidelines
Indiana Department of Health Trauma System Development Grant
SUBMISSION DEADLINE: Rolling submission.
$$$ / N
The Indiana Department of Health’s Division of Trauma and Injury Prevention has been provided funding to support quality improvement projects and the ongoing development of the statewide trauma system. To aid in the implementation of trauma system projects, the Indiana Department of Health will fund the following strategies. Applicants must implement projects that target at least one strategy but can address multiple strategies if appropriate.
- Strategy 1:Trauma System Development
- Strategy 2: Quality Improvement
- Strategy 3: Trauma and Non-Trauma Center Engagement
- Strategy 4: Injury Prevention Programming
This request for application (RFA) is designed for all interested entities wishing to submit proposals for trauma system development under the core strategies outlined above. Funding decisions for all proposals submitted under this program will be made following a review process by the Indiana Trauma Care Commission (TCC) and IDOH.
Eligible applicants might include hospitals, hospital networks, first responder agencies, statewide organizations, and entities with previous experience leading quality improvement activities. An entity may submit more than one proposal.
Applicants will be allocated a set dollar amount based on the project scope and potential impact to address outlined strategies and improve Indiana’s trauma system. NOTE: If your application is selected for funding, IDOH will work with you to create the ID numbers defined below that are requested in the application form. These numbers are necessary prior to the finalization of a contract with the State. If you have these numbers already established, please include them in your application. AOS (Auditor of State) Supplier ID: This number is created by the State Comptroller’s Office and is required for you to receive a contract, purchase order, or receive a payment from the State of Indiana. It requires a W-9 Form AND a Direct Deposit Form Tax ID/EIN: An Employer Identification Number (EIN) is also known as a Federal Tax Identification Number and is used to identify a business entity. The Internal Revenue Service (IRS) issues this number. IDOA Bidder ID: IDOA Supplier Portal, a ten-digit number assigned to companies when they register to bid on solicitations for new state contracts without having to detail certain corporation specifics on each submitted bid. You must have an IDOA Bidder ID. Register here
Contact: : indianatrauma@health.in.gov
Files for Investigators
- WebCAMP User’s Guide
- Trauma System Development Application
- Trauma System Development Guidelines
- Trauma System Development Budget Template (NOTE: FY24 and FY25 budget totals can be different based on the needs of the proposal. The budget totals for each year do not need to match.)
- Trauma System Development Informational Webinar
Click here to start a submission
Click here to return to your submission
Large Collaborative Grant RFA
SUBMISSION DEADLINE: Rolling Submission
$$ / IUSM
This Executive Associate Dean for Research (EADR) sponsored program is intended to support large, collaborative, interdisciplinary grants including, but not limited to, program project grants (P01s), center grants (P30s, P50s, P60s), and cooperative agreements (U54s). The goal of this initiative is to bring together faculty of Indiana University School of Medicine (IUSM) to collaborate and develop novel concepts that advance the mission and research goals of IUSM. These funds must be used for experiments to generate data to support the grant application. Support for this program is dependent on the availability of funds from the EADR. Please see RFA linked below for details.
Contact: trnsldev@iu.edu
Files for Investigators
Click here to return to your submission
Center for Diabetes & Metabolic Diseases Pilot & Feasibility Grant
LETTER OF INTENT (LOI) DEADLINE: Monday February 24, 2025 @ 5:00 PM EST
jelmendo@iu.edu
FULL SUBMISSION: Monday March 24, 2025 (online)
$$ / IUSM / IU / ND / PU / IBRI
A primary research-related activity of the Center for Diabetes and Metabolic Diseases (CDMD)’s Pilot and Feasibility (P&F) program is to foster the development of new diabetes-related investigators and provide seed-support for innovative, high-risk projects.
The CDMD P&F program has three different grant mechanisms:
- Parent P&F Grants: This mechanism invites applications directed towards basic biomedical, clinical, and/or translational research questions on cellular and molecular metabolism related to diabetes/obesity/metabolic syndrome, clinical and outcomes research in diabetes and obesity, complications of diabetes and obesity, islet function and survival, and nutrition and physiology of diabetes and obesity.
- Alzheimer’s-Focused P&F Grants : This mechanism invites applications focused on diabetes and metabolic disease aspects of Alzheimer’s disease and its related dementias (AD/ADRD)–frontotemporal dementia, Lewy body dementia, vascular cognitive impairment with dementia, and multiple etiology dementias.
- Physician-Scientist P&F Grants: This mechanism invites applications from exceptional emerging physician-scientists holding an MD (or equivalent) or MD/PhD with a patient-oriented diabetes and/or obesity-related clinical research project, who are early in their clinical research careers and show great promise to develop into future independent investigators.
The program is directed at:
- Category 1: New investigators without current or past NIH research support as a PD/PI with any current or past support from other sources being modest
- Category 2: Established investigators with no previous work in diabetes who wish to apply their expertise to a problem in diabetes research
- Category 3: Established investigators in diabetes who propose testing innovative ideas that represent clear departure from ongoing research interests
- Category 4: Investigators developing new research techniques/technologies that could be used in a CDMD Core facility
Awards are up to $50,000 for one year
Contact: Jeff Elmendorf jelmendo@iu.edu
Files for Investigators
Click here to return to your submission
Stark Neurosciences Pre-Clinical Neuroimaging Pilot Grant
SUBMISSION DEADLINE: March 31, 2025
$ / IUSM / IU / PU / ND
The goal of the Pre-Clinical Neuroimaging Research Pilot Study program is to facilitate the generation of new knowledge in the neurosciences through the development of funded research programs. This mechanism will provide seed-support up to $10,000 for innovative, high-risk animal imaging projects using the Bruker BioSpec 9.4T PET-MRI scanner using the IIBIS In-Vivo Imaging Core.
Applicants (the contact PI) from one of the following three categories are eligible to apply:
Contact: Contact Information: Yu-Chien Wu, Scientific Director for the Roberts Translational Imaging Facility yucwu@iu.edu
Files for Investigators
Click here to return to your submission
Indiana CTSI (IUSM) Core Equipment Grant
SUBMISSION DEADLINE: March 31, 2025
$ / $$ / $$$ / IUSM
The Indiana CTSI is seeking proposals from Indiana CTSI Designated IU School of Medicine Cores requesting support for the purchase of equipment that will enhance the research environment and contribute to the research mission of the School and the Indiana CTSI.
Proposals requesting equipment costing between $5,000 - $100,000 will be accepted. Proposals for equipment costing more than $100,000 will be entertained if matching funds to cover the balance are identified.
Eligibility:
- Only Cores based within the IU School of Medicine are eligible.
- Only Indiana CTSI Designated Cores are eligible.
Contact: Translational Research Development / 317-278-2822 trnsldev@iu.edu
Files for Investigators
Click here to return to your submission
Translational Population Health Research Award
SUBMISSION DEADLINE: March 31, 2025
$$$ / C / IUSM / IU / PU / ND / N
Population health research advances the promotion and protection of the health of communities and populations, emphasizing healthy lifestyles, social determinants of health, and health care equity, quality, and accessibility. To facilitate this approach, IU Research at Indiana University-Bloomington, in partnership with the Indiana Clinical and Translational Science Institute (CTSI) is accepting applications for the Translational Population Health Research Award program. Applications may focus on any aspect of population health, but meritorious projects should result in an external submission to NIH, NSF, DoD, USDA or comparable agency and ultimately lead to the improvement of population health outcomes. These applications require one or more of the following features:
- A partnership between an IUB faculty member and a community or public health liaison (e.g., non-profit organization, local public health department) external to IUB
- A transdisciplinary collaboration among two or more investigators from different IUB departments or schools
- A collaborator at another Indiana CTSI partner institution (IUSM, IUI, University of Notre Dame, Regenstrief Institute or Purdue).
Contact Information: Joel Ybe jybe@iu.edu
Files for Investigators
Click here to return to your submission
Pilot Funding for Research Use of Core Facilities
SUBMISSION DEADLINE: March 31, 2025
$ / IUSM / IU / PU / ND / R
The Indiana CTSI Pilot Funding program is intended to promote the use of technologies and expertise afforded by the Indiana CTSI Core Facilities available at all partner institutions. Successful proposals will demonstrate outstanding scientific merit that can be linked to generating extramural funding or novel intellectual property (IP). Success of the program will be viewed, in part, by the fostering of new funded grants or providing significant contributions to grant renewals. Therefore, proposals will be judged with equal measure on scientific merit and the likelihood of generating new IP or extramural grant support. Funding is for a maximum requested amount of $10,000; projects are typically two years in duration. Funding is for utilization of designated Indiana CTSI core facilities only. Information describing each core is available at https://indianactsi.org/servicecores/
Contact: Translational Research Development / 317-278-2822 trnsldev@iu.edu
Files for Investigators
Click here to return to your submission
Cancer Center Junior Faculty Pilot Award
EXTENDED NOTICE OF INTENT (NOI) SUBMISSION DEADLINE: March 28, 2025 @ 5PM emailed to vlclemen@iu.edu
EXTENDED FULL SUBMISSION DEADLINE: May 15, 2025 @ 5PM
$$ / CC
The IU Simon Comprehensive Cancer Center and the Cancer Center Junior Faculty Special Interest Group (JFSIG) are inviting proposals for pilot/feasibility research projects in any area of basic, translational, or clinical cancer research (diagnostics, therapeutics), and population science research (prevention, survivorship, quality of life, epidemiology) that would serve to advance the applicants’ career goals.
The principal investigator must be an Associate level member in a Cancer Center Research Program (CPC, EDT, HHM or TMM) or an Affiliate Cancer Center member at the level of: Assistant Professor, Research Assistant Professor, Assistant Scientist, Associate Research Professor, or Research Scientist. Current post-docs and residents/fellows are also eligible, provided they will have a full-time faculty appointment and will be an Associate or Affiliate level Cancer Center member at the time of full application submission.
Notification of Intent can be submitted without Cancer Center membership approval; however, membership approval must be received by the full application deadline of May 15, 2025. To apply for Cancer Center membership, investigators will need to fill out an application via this link and must do so by March 28th, 2025. Please note that membership is not guaranteed; applicants must meet membership criteria as outlined on the website. Applications are reviewed by Cancer Center leadership and the investigator will be notified of member status ~3-4 weeks after application submission.
The duration of this pilot funding is one year, and the budget should not exceed $50,000.
Contact: Contact: Vicki Clements
vlclemen@iu.edu
Files for Investigators
Biomedical Research Grant (BRG)
SUBMISSION DEADLINE: May 1, 2025
$$ / IUSM
The Biomedical Research Grant program is open to all IU School of Medicine (IUSM) faculty that are full-time, regardless of tenure status, having an appointment of Assistant/Associate/Full Professor and Assistant/Associate/Full Scientist. In general, two categories of research projects will benefit from this program: 1) research projects of investigators new to IUSM who do not yet have extramural funding and who need support to acquire the preliminary data necessary to compete for extramural funding; 2) research projects of established IUSM investigators who are between funding periods from extramural sources.
Applications are considered small grants and should have a maximum requested amount of $50,000 and be limited to one (1) year duration
Contact: 317-278-2822 trnsldev@iu.edu
Files for Investigators
Click here to return to your submission
Research Enhancement Grant (REG)
SUBMISSION DEADLINE: May 1, 2025
$$ / IUSM
The IUSM Research Enhancement Program is designed to stimulate research productivity at the statewide Centers for Medical Education (regional campuses) including the Bloomington Medical Sciences Program. This does not include the IU Indianapolis campus. All full-time Center/Medical Sciences faculty, regardless of tenure status, having an appointment of Assistant/Associate/Full Professor or Assistant/Associate/Full Scientist at time of submission, are eligible to apply for a Research Enhancement Grant. Primary appointment must be in the School of Medicine. Faculty in visiting ranks are not eligible for funding through this mechanism.
Applications are considered small grants and should have a maximum requested amount of $50,000 and be limited to one (1) year duration
Contact: 317-278-2822 trnsldev@iu.edu
Files for Investigators
Click here to return to your submission
Global Health Reciprocal Innovation Demonstration Grants
LETTER OF INTENT (LOI) SUBMISSION DEADLINE: February 24, 2024 via email to Sarah Glock sardowns@iu.edu and Dr. Laura Ruhl ljruhl@iu.edu
FULL SUBMISSION DEADLINE: April 14, 2025 online
$$ / C / I / IU / IUSM / ND / PU
This request for applications seeks to leverage the global health research partnerships of three of the Indiana CTSI partner institutions (IU, Purdue, and Notre Dame) to develop, test and translate innovations with a high potential to (1) address a significant health challenge that is shared across Indiana and global settings and (2) that disproportionately affects marginalized/ underserved populations. Projects can focus on a specific disease condition(s) or health or social system challenge that affects health outcomes and/or access to and quality of health care. Principal Investigators from Indiana CTSI institutions must submit a multiple PI (MPI) application for this RFA, ensuring a minimum of 2 MPIs. At least one PI must be from an Indiana CTSI institution, and another PI should represent a LMIC institution/organization or a community-based organization (CBO) in Indiana. Submission of a letter of intent is required in order to receive approval for the submission of a full proposal. Awards are up to $50,000 for a period of two years.
Contact: Sarah Glock sardowns@iu.edu and Dr. Laura Ruhl ljruhl@iu.edu
Global Health Reciprocal Innovation Planning Grants
SUBMISSION DEADLINE: April 14, 2025
$ / C / I / IU / IUSM / ND / PU
The goal of this request for applications (RFA) is to facilitate the planning and designing of reciprocal innovation projects focusing on one of the identified priority areas. Projects must be led by a principal investigator from one of the three research Indiana CTSI institutions (IU, Purdue, and University of Notre Dame) as part of a collaborative partnership with local partners (e.g., Indiana state health partners, nonprofit organizations, educational institutions, health systems, government agencies) and global partners from low- or middle-income countries (LMIC). Successful applicants will demonstrate an understanding of shared health challenges in underserved communities in Indiana and LMIC settings as well as a commitment to the development of new programs or partnerships that will result in the development and demonstration of reciprocal innovation projects in the future. This award is designed to support the preliminary phase of partnership development and project planning. It may be used to support: travel to engage partners, development of project teams, identifying promising health innovations for demonstration, development of evidence to support the demonstration of a reciprocal innovation in Indiana or LMIC setting, training to prepare for a reciprocal innovation demonstration project, and other activities needed to prepare competitive demonstration grant applications for reciprocal innovation. Applicants may request up to $10,000 for a period of 1 year.
Contact: Sarah Glock sardowns@iu.edu and Dr. Laura Ruhl ljruhl@iu.edu
Files for Investigators
Click here to return to your submission
Community Health Partnerships (CHeP) Trailblazer Planning Grant
LETTER OF INTENT (LOI) DEADLINE: September 17, 2025 via email to
chep@iu.edu
FULL SUBMISSION DEADLINE: October 1, 2025
$ / IUSM / C / IU / PU / ND / N
The Indiana CTSI Community Health Partnerships (CHeP) is soliciting proposals for the development of community-university partnerships to improve health, examine social determinants of health (SDoH), or enhance health equity, to result in future collaborative research proposals. The award can be used to establish new partnerships or to strengthen/expand existing community-university partnerships to solve critical health problems affecting Indiana residents. This award will not fund research pilot projects; instead, it will fund activities to help develop partnerships between organizations that have potential to later engage in joint research projects to address health, health equity, or SDoH. The expected outcome of this award is the development of a future research proposal for opportunities such as the Community Health Partnerships Trailblazer Award (Trailblazer Award). Examples of partnership development activities we are interested in funding include meetings, conferences, travel expenses, stakeholder interviews, and quality improvement assessments. There must be at least one university-based partner and one community-based partner. All partners must currently be employed in Indiana-based institutions or organizations. Awards will be up to $5,000 for one year to allow for partnership growth and collaborative grant proposal development.
Contact: chep@iu.edu
Files for Investigators
Click here to return to your submission
Community Health Partnerships (CHeP) Trailblazer Award
LETTER OF INTENT(LOI) DEADLINE: May 19, 2025 via email to
chep@iu.edu
FULL SUBMISSION DEADLINE: June 2, 2025
$ / IUSM / C / IU / PU / ND / N
The Indiana CTSI Community Health Partnerships (CHeP) is soliciting proposals for collaborative, community-engaged research projects focused on topics that have potential to improve health, examine social determinants of health (SDoH), or enhance health equity. This RFA encourages and prioritizes projects that have outlined a sustainability plan that incorporates or utilizes existing Indiana CTSI infrastructure (i.e., Connections IN Health, Monon Collaborative, etc.) and/or connections to statewide health initiatives. This RFA accepts projects which propose to serve any of the counties of Indiana, and given the paucity of projects in public health regions 1 (Lake, Porter, LaPorte, Newton, and Jasper counties) and 7 (Vermillion, Parke, Putnam, Vigo, Clay, Owen, Sullivan, and Greene counties), we especially encourage projects with a focus on those regions. Eligible projects will propose to: (1) implement exploratory research that has the potential to identify or reduce health inequities, or impact SDoH; (2) evaluate a program that has the potential to improve health equity or impact SDOH; or (3) implement and do a preliminary evaluation of a health-related program. Health equity, briefly defined, is “the state in which everyone has a fair and just opportunity to attain their highest level of health” (CDC). Projects that propose to achieve their objectives by changing (or demonstrating the potential to change) policy, systems, and/or the environment are encouraged. (See FAQ page for more on health equity.) There must be both 1) a university lead and 2) a community lead for the project, both partners must currently work in an Indiana-based institution or organization. Funding may be requested up to $25,000 over two years.
Contact: chep@iu.edu chep@iu.edu
Files for Investigators
Click here to return to your submission
A statewide partnership with Indiana University, Purdue University, the University of Notre Dame, and the Regenstrief Institute
HITS Building, 410 West 10th Street, Suite 1000, Indianapolis, IN 46202 (317) 278-CTSI (2874)
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