Medical Technology Advance Program

Medical Technology Advance Program2020-08-12T14:57:21-04:00

Medical Technology Advance Program

The Indiana CTSI Medical Technology Advance Program (MTAP) has assembled a portfolio of technical, regulatory, and related educational resources to enable investigators to develop technologies and speed their progress towards clinical implementation.

MTAP combines technical, regulatory, pre-clinical and translational expertise from the Weldon School of Biomedical Engineering , the College of Veterinary Medicine at Purdue University and IU School of Medicine

Our Services:

  • Facilitate access to advanced biomedical engineering capabilities at Purdue University for the design of medical devices and drug-delivery systems.
  • Assist investigators with regulatory, preclinical and clinical trial planning early in the device development process.
  • Support investigators with a complementary set of educational resources that include courses in medical device regulatory approvals and compliance, preclinical and clinical study design, bioethics and human subjects testing, and biomedical entrepreneurship and commercialization.
  • Foster investigator partnerships with regional medical device and pharmaceutical companies, and subsequent widespread patient access to these technologies.
  • Diminish the gap between engineering discovery and clinical impact through integrative approaches.
Extensive expertise and support are available in six inter-related domains:
The Weldon School of Biomedical Engineering at Purdue has a long and productive history in the design and development of medical devices for a wide array of clinical applications.  With in-house capabilities for materials and electronics fabrication and extensive experience that includes electronic, optical, and mechanical instrumentation; design and fabrication of measurement systems; electrodes; wearable sensors; tissue stimulation and response; implantable electronics; and, experiment and protocol design and logistics, the team can provide a wide range of research and development services. For more information, please contact Kirk Fosterfoster@purdue.edu )
The Weldon School of Biomedical Engineering at Purdue has substantial experience in regulatory issues as they relate to the translation of medical devices from the laboratory into clinical utility. An array of courses are offered to investigators in such topics as regulatory approvals, regulatory compliance, and preclinical and clinical study design for regulatory consideration. In addition, consultation services are available to aid investigators in navigating the technology development path to design approaches and yield data that streamline the FDA approval process. For more information, please contact Aaron Lottes ( lottes@purdue.edu )
The design, construction, and testing of new drug delivery systems involve an integration of engineering and pharmaceutics. The Weldon School of Biomedical Engineering in collaboration with the Purdue College of Pharmacy offer unique capabilities to design and develop innovative systems for such needs as controlled release, injectables, and connected care applications. For more information, please contact Dr. Kinam Park kpark@purdue.edu )
The preclinical studies team at the Purdue Weldon School of Biomedical Engineering collaborates with investigators and provides expertise, resources, and assistance in conducting preclinical studies for medical device development in a wide variety of animal models and procedures.  Technical services available include, but are not limited to:
  • Preview of protocol applications prior to submission
  • Pre-study consultation
  • Training support
  • Pre-surgical and surgical animal study preparation
  • Anesthesia
  • Access to imaging services
  • Aftercare of animals in recovery studies
  • Post-surgical questions/care
For more information please contact Bill Schoenleinschoen@purdue.edu ). In addition, the Pre-Clinical Research Laboratory is a multidisciplinary laboratory where Purdue College of Veterinary Medicine faculty members collaboratively conduct advanced clinical and applied research using induced animal models. For more information, please contact Dr. Gert Breur ( breur@purdue.edu )
The Clinical Trials Group (CTG) is part of the College of Veterinary Medicine  Medical Discovery Resource Unit. The Clinical Trials Group facilitates animal clinical trials within the Purdue Veterinary Teaching Hospital and provides expertise and technical support for translational clinical investigations using spontaneous, naturally-occurring diseases in client-owned animals and for trials leading to novel drugs or devices for use in companion and food animals. Patients are actively recruited for clinical trial research in the ongoing effort to improve the care and treatment of all animals, large and small. View the full list of current clinical trials to learn more. For more information, please contact Dr. George Moore ( gemoore@purdue.edu )
The Histology Laboratory is a division of the Center for Comparative Translational Research at the Purdue College of Veterinary Medicine . The lab, designed to assist Purdue and outside scientists in their preclinical and discovery translational research efforts, is staffed by two full-time technicians. Submitted tissue samples are embedded in paraffin, plastic or OCT medium (frozen tissue). Embedded tissues are sectioned with a rotary microtome (paraffin and plastic), cryostat (frozen tissues), or with EXAKT grinding (plastic embedded undecalcified bone and implants). A variety of histological stains is available and automated immunocytochemistry services are offered. Veterinary pathologists with experience in device associated pathology, drug and toxicologic pathology and infectious disease pathology are available to collaborate and consult on projects. For more information, please contact Dr. Abigail Cox adcox@purdue.edu )

Visit our technology centers sites below for more details on each center:

Get Involved with Indiana CTSI