Research Glossary

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Research Glossary2018-08-21T08:07:30-04:00

Clinical research – Clinical research “aims to advance medical knowledge by studying people, either through direct interaction or through the collection and analysis of blood, tissues, or other samples.” (National Institutes of Health)
Clinical trial – A clinical trial “involves research participants. It follows a pre-defined plan or protocol to evaluate the effects of a medical or behavioral intervention on health outcomes. By taking part in clinical trials, participants not only play a more active role in their own health care, but they also can access experimental treatments and help others by contributing to medical research.” (National Institutes of Health)
Community engagement – Community engagement is “the process of working collaboratively with and through groups of people affiliated by geographic proximity, special interest, or similar situations to address issues affecting the well-being of those people.” (U.S. Centers for Disease Control and Prevention)
Cores – The Indiana CTSI enables IU, Purdue and Notre Dame investigators access to more than 80 service cores throughout the state. These service cores provide research expertise and equipment
CTSA Program – The Clinical and Translational Science Awards (CTSA) Program is part of the National Institutes of Health’s (NIH) National Center for Advancing Translational Science (NCATS). The Indiana CTSI is been continuously funded since 2008 by multiple multi-million dollar grants through this program, which funds more than 50 member sites throughout the nation.
KL2 Scholars – KL2 Scholars are exceptional early-career investigators that compete for and are chosen to receive support for their work through the Indiana CTSI.
Indiana Biobank – The Indiana Biobank was established in July 2010 to create a “bank” of biospecimens that are linked to participants’ electronic medical information. Participants are recruited throughout the state of Indiana. Data and specimens are made available to academic and commercial researchers. In addition to banked specimens, the Indiana Biobank offers prospective custom collections to obtain biospecimens and data meeting a researcher’s specific needs.
NCATS – The National Center for Advancing Translational Science (NCATS) is part of the National Institutes of Health (NIH). The Indiana CTSI has been continuously funded since 2008 by multiple multi-million dollar grants through NCATS’ Clinical and Translational Science Awards (CTSA) Program, which funds more than 50 member sites throughout the nation.
PDTs – The Indiana CTSI’s Project Development Teams (PDTs) provide investigators access to experts who can help implement high-quality pilot projects that generate successful external grant submissions. They provide support for researchers and their projects at all stages of the translational research process.
Specimen Storage Facility (SSF) – The Specimen Storage Facility (SSF) currently maintains four mechanical freezer storage sites, a LN2 freezer storage site, and a nucleic acid extraction laboratory. Both investigator- and SSF-owned freezers are monitored and maintained by SSF staff 24/7 to virtually eliminate specimen loss due to freezer failures. Quality is maintained via our contracted independent QA oversight and guidance. Our facility and procedures are ISBER compliant (International Society for Biological and Environmental Repositories).
TL1 research – Basic science at the molecular and cellular levels.
TL2 research – Animal subjects research.
Translational research – Translational research is “the process of turning observations in the laboratory, clinic and community into interventions that improve the health of individuals and the public—from diagnostics and therapeutics to medical procedures and behavioral changes.” (National Center for Advancing Translational Science)

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