Cryo-EM at IUSM Center for Electron Microscopy (iCEM)
Speaker: Natalia de Val, Senior Scientist Thermo Fisher Scientific
Hosted by: IUSM Center for Electron Microscopy (iCEM) Dr. Quyen Hoang, Ph.D, Director IU School of Medicine
Description: As the saying goes, a picture is worth a thousand words. Transmission electron microscopy (TEM) is an important technology in cell and structural biology that creates images of cells by passing an electron beam through the sample. Recent advancements in cryo-EM have enabled imaging of proteins and cellular structures at atomic resolution from purified proteins in vitro as well as in situ as they exist in the cell. This seminar will describe the capabilities of the Glacios cryo-TEM at iCEM and provide an overview of additional new capabilities that are possible with add-on accessory instruments. Examples of recent results and insights obtained from this instrument related to cancer and other diseases will be highlighted.
