The Indiana Clinical and Translational Sciences Institute (CTSI) Research Core Technology Seminar Series is resuming for the fall. The next event will be on Friday, November 19 from 12:00 pm – 1:00pm.
Seminar title: NMR of molecules large and small: structure and interactions
Speaker name and title: Evgenii Kovrigin, PhD Director of Magnetic Resonance Research Center
Speaker institution: University of Notre Dame
Hosted by: Notre Dame Magnetic Resonance Research Center
Nuclear Magnetic Resonance (NMR) spectroscopy enables analysis of natural products, metabolites, synthetic drug candidates, peptides, and proteins to determine their purity, structures, and interactions. Compounds in complex mixtures may be identified based on diffusion coefficients as well as by directly fitting the component spectra. Binding interactions are sensitively detected and mapped on the molecular structures while binding kinetics are accessible from NMR line shapes in titration experiments. This seminar will highlight the most NMR prominent capabilities relevant to biomedical research and drug design available to CTSI researchers at the Magnetic Resonance Research Center at the University of Notre Dame.
The purpose of this seminar series is to inform investigators about how existing or new technologies offered by the core facilities at Indiana University, Purdue University and the University of Notre Dame could be useful in advancing their research.
