Review: Cardiac MRI of children with multisystem inflammatory syndrome (MIS-C) associated with COVID-19: cCase series

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Review: Cardiac MRI of children with multisystem inflammatory syndrome (MIS-C) associated with COVID-19: cCase series

Review: Cardiac MRI of children with multisystem inflammatory syndrome (MIS-C) associated with COVID-19: cCase series

This case series reviewed the cardiac MRIs of 4 children and adolescents with multisystem inflammatory syndrome in children (MIS-C), with findings favoring post-infectious myocarditis without signs of coronary abnormalities. 

  • Study took place in France
  • All 4 children underwent transthoracic echocardiography and cardiac MRI.
  • Acute myocarditis occurred <1 week after onset of fever and gastrointestinal symptoms.
  • The mean age was 9 years, range 6-12 years, with three being girls.
  • Initial transthoracic echocardiography (ECHO) showed:
    • Severely decreased LV ejection fraction (LVEF) in one patient (LVEF < 30%)
    • Low-normal LVEF in three patients (LVEF > 50%)
    • All 4 had transient systolic dysfunction
  • On follow-up ECHO, all patients recovered normal ventricular function and kinetics in 48 hours to 5 days.
|2020-06-14T08:53:19-04:00June 11th, 2020|COVID-19 Literature|0 Comments

About the Author: Megan McHenry

Megan McHenry
Megan S. McHenry, MD, MS, FAAP is a pediatrician and an Assistant Professor of Pediatrics in the Ryan White Center for Pediatric Infectious Disease and Global Health at Indiana University School of Medicine. Dr. McHenry's research focuses on early childhood development in children living in resource-limited settings. This work is frequently aligned with community-engaged research and dissemination and implementation science frameworks. She primarily conducts research in collaboration with the Academic Model for Providing Access to Healthcare (AMPATH) Research Network in Kenya. Dr. McHenry currently has a career development award through the National Institutes of Health to develop a neurodevelopmental screening program for children born to HIV-infected mothers in Kenya. Dr. McHenry is also the Director of Pediatric Global Health Education and a co-Director of the Morris Green Physician-Scientist Development Program at Indiana University School of Medicine. In additional to global health lectures, she also educates residents and students on early childhood development, basic biostatistical techniques, research methodologies, and research ethics. She mentors multiple pediatric fellows, residents, and medical students interested in early childhood development within global contexts.

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