This observational cohort study sought to determine mortality rates among adults with critical illness from coronavirus disease 2019.

The authors examined 217 critically ill patients with confirmed severe acute respiratory syndrome-CoV-2 disease who were admitted to any of 6 COVID-designated ICUs at 3 hospitals within an academic health center network in Atlanta, Georgia from March 6, 2020, to April 17, 2020.

Main findings included:

• Mortality for those who required mechanical ventilation was 35.7% (59/165)
• 4.8% of patients (8/165) were still on the ventilator at the time of the report
• Overall mortality was 30.9% (67/217)
• 60.4% (131/217) patients survived to hospital discharge
• Mortality was significantly associated with older age, lower body mass index, chronic renal disease, higher Sequential Organ Failure Assessment score, lower PaO2/FIO2 ratio, higher D-dimer, higher C-reactive protein, and receipt of mechanical ventilation, vasopressors, renal replacement therapy, or vasodilator therapy