This systematic review evaluates the literature and report the maternal and neonatal outcomes associated with COVID-19.
The authors examined 9 articles investigating 92 COVID-19-positive pregnant women and reporting their pregnancy and neonatal outcomes. Overall, they found evidence to suggest that COVID-19-positive pregnant women present with fewer symptoms than the general population and may be RT-PCR negative despite having signs of viral pneumonia. The incidence of preterm births, low birth weight, C-section, NICU admission were also higher than the general population.
Specific findings included:
- 67.4% (62/92) of women were symptomatic at presentation
- RT-PCR was inferior to CT-based diagnosis in 31.7% (26/79) of cases
- Maternal mortality rate was 0% and only one patient required intensive care and ventilation
- 63.8% (30/47) had preterm births, 61.1% (11/18) fetal distress and 80% (40/50) a Caesarean section
- 76.9% (11/13) of neonates required NICU admission and 42.8% (40/50) had a low birth weight
- There was one indeterminate case of potential vertical transmission
- Mean time-to-delivery was 4.3±3.08 days (n = 12) with no difference in outcomes (p>0.05)