Review: SARS-Cov-2 in Spanish intensive care – early experience with 15-day survival in Vitoria

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Review: SARS-Cov-2 in Spanish intensive care – early experience with 15-day survival in Vitoria

Review: SARS-Cov-2 in Spanish intensive care – early experience with 15-day survival in Vitoria

This study reports the epidemiology of the first patients who were admitted to the ICU with confirmed infection by SARS-CoV-2 in Vitoria, Spain. Findings suggests that a strategy of right oxygenation avoiding non-invasive mechanical ventilation was life-saving. After 15 days of ICU admission, half of patients remained intubated, whereas one third died.

The authors examined data from all consecutive COVID-19 adult patients between March 4, 2020 and March 31, 2020. Patients were followed until ICU death or discharge. Mortality was assessed in those who completed 7-days of ICU stay.

They identified 48 patients with confirmed SARS-CoV-2. Characteristics of these patients included:

  • Median [interquartile range (IQR)] age was 63 [51-75] years.
  • 27 were male.
  • Symptoms began a median of 7 [5-12] days before ICU admission.
  • The most common comorbidities were obesity (n = 48%), arterial hypertension (n = 44%) and chronic lung disease (n = 37%).
  • All patients were admitted by hypoxemic respiratory failure.
  • None received non-invasive mechanical ventilation.
  • Forty-five (94%) underwent intubation, 3 HFNT, 1 (2%) extracorporeal membrane oxygenation (ECMO) and 22 (49%) required prone position.
  • After 15 days, 14/45 (31%) intubated patients died (13% within one week), 10 (22%) were extubated, and 21/45 (47%) underwent mechanical ventilation.
  • 6 patients had documented co-infection.
  • Procalcitonin plasma above 0.5 µg/L was associated with 16% vs. 19% (p = 0.78) risk of death after 7 days.
  • Seven-day mortality in SARS-CoV-2 requiring intubation was lower than 15%, with 80% of patients still requiring mechanical ventilation.
|2020-04-13T13:31:56-04:00April 13th, 2020|COVID-19 Literature|Comments Off on Review: SARS-Cov-2 in Spanish intensive care – early experience with 15-day survival in Vitoria

About the Author: Erika Cheng

Erika Cheng

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