This article highlights the United Nations Communications Response Initiative to combat COVID-19 misinformation.

Secretary-General of the United Nations, Antonio Guterres, raises concerns that the deadly COVID-19 pandemic is creating another dangerous epidemic of misinformation. A global “misinfo-demic” is spreading as people around the world are seeking information to alleviate fears about COVID-19. Not only is false information being perpetuated but so too is harmful health advice. To counteract wild conspiracy theories and hateful, stigmatizing rhetoric created by misinformation, the United Nations created a Communications Response initiative to flood the Internet with facts about COVID-19. Guterres urges individuals to trust in science, responsive and responsible governance and leadership, and each other. To help combat this infodemic of misinformation, government leaders must also communicate evidence-based information to publics.