Biophysics Instrumentation Core (BIC) Facility

University of Notre Dame

Patricia L. Clark, PhD

bic.nd.edu

The BIC Facility offers 13 complementary instruments dedicated to characterizing biomolecular conformations and interactions, as well as equipment for the isolation and purification of macromolecules. These instruments include a Jasco J-815 circular dichroism spectropolarimeter and Bio-Logic stopped-flow kinetic system, a Biacore T200 surface plasmon resonance system, a MicroCal PEAQ-ITC microscale isothermal titration calorimeter, an AKTA pure 25 M1 protein purification system, two TTP Labtech crystallization robots, an Amersham Typhoon IP phosphoimager, an Azure c400 gel documentation system, and five centrifuges and associated rotors, including a Beckman ProteomeLab XL-A analytical ultracentrifuge. The BIC employs one full-time PhD-level Staff Scientist who provides equipment training and technical assistance. The BIC Facility is open to outside academic and industry researchers and welcomes both in-person use and mail-in samples for analysis.

• Giselle Jacobson : gjacobso@nd.edu 574-631-3556