Biophysics Instrumentation Core (BIC) Facility

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Biophysics Instrumentation Core (BIC) Facility

Biophysics Instrumentation Core (BIC) Facility

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University of Notre Dame


Patricia L. Clark, PhD


The BIC Facility offers 14 complementary instruments dedicated to characterizing biomolecular conformations and interactions, as well as equipment for the isolation and purification of macromolecules. These instruments include:

  • Jasco J-815 circular dichroism spectropolarimeter and Bio-Logic stopped-flow kinetic system
  • Biacore T200 surface plasmon resonance system
  • MicroCal PEAQ-ITC microscale isothermal titration calorimeter
  • Beckman ProteomeLab XL-I analytical ultracentrifuge
  • QuantStudio 3 polymerase chain reaction system
  • AKTA pure 25 M1 protein purification system
  • two TTP Labtech crystallization robots
  • Amersham Typhoon IP phosphorimager
  • Azure c400 gel documentation system
  • five Beckman centrifuges and ultracentrifuges

The BIC employs one full-time PhD-level Staff Scientist who provides equipment training and technical assistance. The BIC Facility is open to outside academic and industry researchers and welcomes both in-person use and mail-in samples for analysis.

|2024-03-28T10:47:31-04:00March 28th, 2024|Comments Off on Biophysics Instrumentation Core (BIC) Facility

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