Cryo-EM Facility

Affiliation :  Purdue University

Director:   Dr. Wen Jiang
Director:   Thomas Klose

Website:  https://cryoem.bio.purdue.edu/

Description:
The Purdue Cryo-EM Facility provides state-of-the-art instruments (FEI Titan Krios with Gatan K2 Summit direct electron detector, FEI Volta phase plate) and expertise for high resolution structure determination of viruses, larger macromolecular complexes, nano-particles, as well as tomographic visualization of virus-cell interactions by cryo-electron microscopy (cryo-EM). The facility staff can provide complete service from sample grid preparation to automated data collection. Experienced users are also allowed to perform sample preparation and data collection tasks themselves at reduced rates. Our facility is available to Purdue, other academic institutes, and industry users.

Policies:

• Cryo-EM Core Policies

Services Offered:

• High-resolution single particle cryo-EM imaging (viruses; macromolecular complexes; nano-particles)
• High-resolution cryo-electron tomographic imaging (pleomorphic viruses; virus/host interactions; cell sections)

Contact Information:
Thomas Klose
Email This Core
765-494-8712