Chemical Genomics Facility

/Chemical Genomics Facility/

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Chemical Genomics Facility

Director:   Zhong-Yin Zhang, PhD.
Associate Director:   Lan Chen, PhD.

Website:  https://www.purdue.edu/discoverypark/drug-discovery/resources/cgf/index.php

Description:
The Chemical Genomics Facility\\\\\\\\’s (CGF) mission is to provide expertise and resources to investigators from Purdue and other institutions to access state-of-the- art technologies and instrumentation in high-throughput screening (HTS) and high content screening (HCS), to facilitate the identification of chemical or genomic tools to study biological pathways and the discovery of lead agents for the development of novel therapeutics and diagnostic approaches. The facility is designed to be highly flexible in order to meet the needs of multiple users employing a range of assays from a wide range of disciplines. Our experienced facility staff work closely with each investigator and provide services through all stages of the lead discovery process.

Policies: Services Offered:
  • Consultation on assay development, implementation, validation and miniaturization specific to the target of your interest. Type of assays implemented includes: –In vitro enzymatic activity assays –In vitro protein binding assays –Cell proliferation assays –Cell-based transcription (reporter gene) assays –Image-based cell phenotypic screening assays
  • Pre-plated compound library ready for assays that are performed in 384-(preferred) or 96-well plate format
  • High throughput screening and high content screening using liquid handling robots and automated plate readers and high content imaging acquisition and analysis
  • Assistance with data analysis and compound selection will be provided as needed
  • Post-screen hit validation (dose dependence, binding evaluation, etc.)
Categories for this Core: Keywords for this Core:
high-throughput screening (HTS), high-throughput screening (HTS), high content screening (HCS), high content screening (HCS), biological pathways, biological pathways, discovery, discovery, lead agents, lead agents, novel therapeutics, novel therapeutics, assays, assays, diagnostics, diagnostics, genomics, genomics, chemical, chemical

Contact Information:
Dr. Lan Chen
Email This Core
765-496-6668

By |2019-04-01T17:11:52-04:00October 21st, 2018|Comments Off on Chemical Genomics Facility

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