Affiliation : Purdue University
Zhong-Yin Zhang, PhD.
Associate Director: Lan Chen, PhD.
The Chemical Genomics Facility (CGF) is a charge-for-service facility located at the Purdue Institute for Drug Discovery. The mission of the CGF is to provide expertise and resources to investigators from Purdue and other institutions to access to the state-of-the-art technologies and instrumentation in high-throughput screening (HTS) and high content screening (HCS) campaigns to facilitate the identification of chemical or genomic tools to study biological pathways and the discovery of lead agents for the development of novel therapeutics and diagnostic approaches. The facility is equipped with a variety of chemical libraries including diversity-oriented small molecules, target-based focused libraries, known drugs and bioactives, fragment libraries and siRNA libraries, as well as a full line of advanced robotic instruments. The facility is designed to be highly flexible in order to meet the needs of multiple users employing a range of assays from a wide range of disciplines. Our experienced facility staff work closely with each investigator and provide services through all stages of the lead discovery process, from assay implementation, screening design and execution to hit validation and instrumentation. The facility also provides an opportunity for students and fellows to gain experience and training in HTS and HCS, and promotes highly productive interdisciplinary and collaborative research in drug discovery.
Dr. Lan Chen
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