The Indiana Clinical and Translational Sciences Institute (CTSI) Research Core Technology Seminar Series is resuming for the fall. The next event will be on Friday, October 8 from 12:00 pm – 1:00pm.
This event will be hosted by the Molecular Evolution, Protein Engineering, and Production Facility.
Seminar title: Protein Engineering and Production
Speaker name and title: Raluca Ostafe, PhD, Director of Molecular Evolution, Protein Engineering, and Production Facility (MEPEP)
Speaker institution: Purdue University
Proteins are the building blocks of life. During this seminar we will take a closer look at how we can use these molecules for multiple biotechnological applications including diagnostics, therapy, chemical synthesis, etc. The proteins, however, mostly need to be engineered at both protein or gene level to meet the conditions required for industrial applications or for production. For example, some enzymes require that are active at extreme conditions, such as high temperature or very low pH. Low cost is in general a main concern for multiple applications therefore engineering cells and proteins for high production is very important. This seminar will describe different problems that we encounter when taking proteins from nature and trying to use them for an industrial application and it will discuss the methods that we are using for making them fit for the biotechnological process.
The purpose of this seminar series is to inform investigators about how existing or new technologies offered by the core facilities at Indiana University, Purdue University and the University of Notre Dame could be useful in advancing their research.
