Scientific Abstracts

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Single IRB and the CTSI: Liaison Model for the IRB Reliance Process Christine Caldwell Navigating the NIH Single IRB Policy has been challenging for investigators, study teams, and Human Research Protection Programs (HRPP). In response, the Indiana Clinical and Translational Read More
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Indiana Clinical and Translational Sciences Institute (CTSI) – CTSA-wide podcast opportunity Christine Drury and Aaron Carroll, MD, MS Impact: With a current audience of approximately 10,000 listeners, the Indiana Clinical & Translational Sciences Institute sponsored “Healthcare Triage” podcast reaches more Read More
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Closing the Cross-institutional Referral Loop: Applying Human Factors to Improve Consultation Notes April Savoy Objective: Although referrals for specialty consultations are a core clinical process, they are prone to coordination and communication breakdowns that have led to adverse clinical outcomes. This Read More
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Understanding ECM-Based Drug Resistivity in Breast Cancer Sarah Libring, Aparna Shinde, Miad Boodaghidizaji, Alexandra Plummer, Arezoo Ardekani, Mike Wendt, Luis Solorio Impact: A translatable drug-screening assay, loaded with patient samples and tested against all relevant chemotherapeutics would provide clinicians with Read More
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Phenotypic Characterization of Dysmenorrhea: A Pilot Study Chen X. Chen, PhD, MS, RN, Janet S. Carpenter, PhD, RN, FAAN, Evelyn Toh, PhD, Qunfeng Dong, PhD, Xiang Gao, PhD, MS, David E. Nelson, PhD, Fletcher White, MS, PhD, Smriti Iyengar, PhD, Dennis Fortenberry, Read More
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Evaluating the Effect of Prebiotics on the Gut Microbiome Profile and Beta-cell Function in Newly-Diagnosed Type 1 Diabetes  Heba Ismail, MB BCh, MSc, PhD; Carmella Evans-Molina, MD, PhD; Linda A DiMeglio, MD, MPH; Indiana University School of Medicine Background and Objectives: Read More
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Investigation of a Series of 1,4-diaryl-pyrazolo-pyridinones as Anti-Leishmanial Agents Hannah Corman, Douglas A Shoue, Bruce J Melancon, Mary Ann McDowell  Impact: The first-line chemotherapies used to treat leishmaniasis are highly toxic intravenous antimonials yet drug resistance has begun to develop, causing Read More
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Determinants of Antigenicity in Tumor Neoepitopes for the Development of Personalized/Multiple Peptide Vaccines Grant Keller, Department of Chemistry & Biochemistry and Harper Cancer Research Institute, University of Notre Dame; Hakimeh Ebrahimi-Nik, Department of Immunology, University of Connecticut School of Medicine; Read More
Building a Translational Science pipeline: The Indiana CTSI STEM K-12 Program Elmer Sanders, Vanessa Barth, Leigh-Ann Cruz, Sharon Harrison, Amy Hinshaw, Jacob Olson, Ilesha Sherrer, Elvia Solis, Emily Speidell, James McAteer Impact: The Indiana Clinical and Translational Sciences Institute K-12 Read More
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Twenty-four-hour Urinary Sodium Excretion Estimated from a Spot Urine Sample May Be Used as an Indicator of Intake in CKD Patients Andrea J. Lobene,1 Elizabeth R. Stremke,1 Ranjani N. Moorthi,2 Sharon M. Moe,2 Kathleen M. Hill Gallant1 Objectives/Goals: Sodium (Na) Read More

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