Review: Comparison of chest CT findings between COVID-19 pneumonia and other types of viral pneumonia: A two-center retrospective study

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Review: Comparison of chest CT findings between COVID-19 pneumonia and other types of viral pneumonia: A two-center retrospective study

Review: Comparison of chest CT findings between COVID-19 pneumonia and other types of viral pneumonia: A two-center retrospective study

A retrospective review comparing the pulmonary chest CT findings of patients with COVID-19 pneumonia with those with other types of viral pneumonia found that a peripheral distribution, a lesion range > 10 cm, involvement of 5 lobes, presence of hilar and mediastinal lymph node enlargement, and no pleural effusion were significantly associated with 2019-novel coronavirus pneumonia.

  • Review includes 154 patients with RT-PCR-confirmed COVID-19 pneumonia diagnosed between February 11 and 20, 2020, and 100 patients with other types of viral pneumonia diagnosed between April 2011 and December 2020 from two hospitals in China.
  • The results are adjusted for age, sex, and body mass index [BMI] and other significantly associated clinical and imaging characteristics in univariate regression analysis:
  • A peripheral distribution was associated with an OR of 13.04 (95%CI 4.12, 41.27) for COVID-19 pneumonia, compared with a diffuse distribution.
  • A maximum lesion range > 10 cm was associated with an OR of 9.75 (95%CI 3.06, 31.13) for COVID-19 pneumonia, compared with a maximum lesion range ≤ 5 cm
  • The involvement of 5 lobes was associated with an OR of 8.45 (95%CI 2.28, 31.28) for COVID-19 pneumonia, compared with a maximum lesion range ≤ 2
  • No pleural effusion was associated with an OR of 3.58 (95%CI 1.47, 8.72) for COVID-19 pneumonia compared with the presence of pleural effusion.
  • Hilar and mediastinal lymph node enlargement was associated with an OR of 2.79 (95%CI 1.29, 6.02) for COVID-19 pneumonia.
|2020-05-14T11:14:06-04:00May 13th, 2020|COVID-19 Literature|0 Comments

About the Author: Megan McHenry

Megan McHenry
Megan S. McHenry, MD, MS, FAAP is a pediatrician and an Assistant Professor of Pediatrics in the Ryan White Center for Pediatric Infectious Disease and Global Health at Indiana University School of Medicine. Dr. McHenry's research focuses on early childhood development in children living in resource-limited settings. This work is frequently aligned with community-engaged research and dissemination and implementation science frameworks. She primarily conducts research in collaboration with the Academic Model for Providing Access to Healthcare (AMPATH) Research Network in Kenya. Dr. McHenry currently has a career development award through the National Institutes of Health to develop a neurodevelopmental screening program for children born to HIV-infected mothers in Kenya. Dr. McHenry is also the Director of Pediatric Global Health Education and a co-Director of the Morris Green Physician-Scientist Development Program at Indiana University School of Medicine. In additional to global health lectures, she also educates residents and students on early childhood development, basic biostatistical techniques, research methodologies, and research ethics. She mentors multiple pediatric fellows, residents, and medical students interested in early childhood development within global contexts.

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