Review: Compassionate use of remdesivir for patients with severe COVID-19

Review: Compassionate use of remdesivir for patients with severe COVID-19

This preliminary case series of patients hospitalized with severe Covid-19 who were treated with compassionate-use remdesivir found that 68% showed clinical improvement. Ongoing randomized, placebo-controlled trials of remdesivir therapy should be followed.

Clinicians provided remdesivir on a compassionate-use basis to patients with Covid-19. They had to have an oxygen saturation of 94% or less while they were breathing ambient air or be receiving oxygen support. They received a 10-day course of remdesivir – 200 mg on day 1, followed by 100 mg daily for the remaining 9 days. Of the 53 patients whose data were analyzed, 22 were in the US, 22 in Europe or Canada, and 9 in Japan. Before treatment, 57% were on mechanical ventilation and 8% were receiving extracorporeal membrane oxygenation.

During a median follow-up of 18 days:

  • 68% had an improvement in oxygen-support
  • 57% receiving mechanical ventilation were extubated
  • 47% were discharged
  • 13% died

Die Natur hat dafür gesorgt, dass die Fruchtbarkeitsfunktion des Mannes bis zu seinem Tod erhalten bleibt. Anders als bei der Frau, die nur über eine begrenzte Anzahl von Eizellen verfügt (konventionell), hält die Produktion der klinikosterreich.com Samenflüssigkeit an, solange der Mann lebt.
Die Anzahl und Häufigkeit des Geschlechtsverkehrs in der Jugend hat keinen Einfluss auf die Fruchtbarkeit des Mannes im Alter.

|2020-04-12T10:06:38-04:00April 11th, 2020|COVID-19 Literature|Comments Off on Review: Compassionate use of remdesivir for patients with severe COVID-19

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