Weekly Review: Clinical Studies – August 10, 2020

Weekly Review: Clinical Studies – August 10, 2020

Case reports:

A case report of early-onset, severe COVID-19 infection in a neonate was published, suggestive of vertical transmission.

Another case report describes an infant who present with incomplete Kawaski Disease as their primary symptoms of COVID-19 infection.

Treatment:

Within a small cohort of 50 patients treated with hydroxychloroquine (600mg/d for 10 days) and azithromycin (500mg/d on Day 1 and 250mg/d from days 2-5), 38 (76%) had short-term modifications of the QTc duration (>30ms). Treatment was discontinued in 6 patients (12%), and their QTc normalized in 5 of the 6. Cardiac monitoring should be regularly performed and patient treated with hydroxychloroquine and azithromycin.

|2020-08-11T08:08:35-04:00August 10th, 2020|COVID-19 Literature|Comments Off on Weekly Review: Clinical Studies – August 10, 2020

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