CTSI Pilot Funding Awards

CTSI Pilot Funding Awards2024-04-24T08:28:16-04:00

Translational Research Development Program

The Indiana Clinical and Translational Sciences Institute (CTSI) is a vital partnership among the leading research universities of Indiana University, Purdue University and the University of Notre Dame as well as life sciences, businesses and community organizations across the state.

To fulfill its mission, it supports individuals and teams in all areas of translational research related to the prevention, diagnosis, and management of human disease.

A current list of current awardees is below to provide examples of the type of projects that the CTSI has invested to help improve human health, as well as to showcase the translational research being done across Indiana.

Current Translational Research Awardees

2023 – Biomedical Research Grant (BRG)

Bidwell, Joseph Indiana University School of Medicine Models for Osteoporosis Therapy
Bopda Waffo, Alain Indiana University School of Medicine Mapping druggable targets and subunit motifs of Ebola virus glycoprotein as a precursor for vaccine development
Brustovetsky, Nickolay Indiana University School of Medicine CRMP2 and mitochondrial dynamics in Alzheimer’s disease
Needham, Brittany Indiana University School of Medicine Electroactive bacteria in gut-host communication
Obeid, Makram Indiana University School of Medicine Hemorrhage-induced inflammasome activation to enhance the emergence of post-traumatic epilepsy in a periadolescent mouse model
Pelletier, Stephane Indiana University School of Medicine Development and universal application of short artificial introns for the generation of conditional alleles in mice
Schmitt, Rebecca Indiana University School of Medicine Evaluation of GNE mutation classes and aberrant autophagy in GNE myopathy
Snell, Laura M Indiana University School of Medicine Exploring beta-2 microglobulin regulation of CD4 T cell exhaustion in chronic viral infection
Snyder, Scott Indiana University School of Medicine 89Zr-Dinutuximab as a companion diagnostic for anti-GD2 immunotherapy in Sarcoma
Yang, Chunlin Indiana University School of Medicine Investigation of the RNA polymerase II CTD of the human pathogen Toxoplasma gondii

2022 – Biomedical Research Grant (BRG)

Absalon, Sabrina Indiana University School of Medicine Deciphering the molecular mechanism of nuclear multiplication during the blood-stage replication of malaria parasite
Bopda Waffo, Alain Indiana University School of Medicine A Novel Biosensor to Monitor the Vaccine Efficacy of Coronavirus Diseases
Borschel, Gregory Indiana University School of Medicine Corneal Neurotization Assessment Registry (CorNeA): Design, Infrastructure, and Feasibility
Burgin, Sarah Indiana University School of Medicine An assessment of molecular diagnostics in otitis media
Capitano, Maegan Indiana University School of Medicine Novel Predictors of Umbilical Cord Blood Hematopoietic Cell Engraftment Efficacy
Dahl, Richard Indiana University School of Medicine MiRNA Programming of the Myeloid anti-Tumor Response
Elmendorf, Jeffrey Indiana University School of Medicine Refining the molecular basis of insulin resistance & diabetes
Harrison, Nicholas Indiana University School of Medicine Central Apnea as a mediator of Right Ventricular-pulmonary vascular uncoupling in Acute Heart Failure (CARV-AHF)
Janosevic, Danielle Indiana University School of Medicine Transcriptomic staging of sepsis-associated acute kidney injury
Layer, Justin Indiana University School of Medicine Probing an Oncoprotein Complex Using Synthetic Antibodies
Lim, Kenneth Indiana University School of Medicine Therapeutic targeting of CKD-associated cardiomyopathy by KL1
Maiers, Jessica Indiana University School of Medicine Elucidating the crucial role of ER proteostasis in Hepatic Fibrogenesis
Mayo, Lindsey Indiana University School of Medicine Mdm2 E3 neddylating activity drives the initiation of metastasis
Nelson, Rick Indiana University School of Medicine Function of TMPRSS in Genetic Hearing Loss
O’Hagan, Heather Indiana University School of Medicine Using lysine demethylase 1 inhibition to target enteroendocrine cells in mucinous colorectal cancer
Pin, Fabrizio Indiana University School of Medicine Deletion of FNDC5/Irisin protects against cancer-induced cachexia syndrome
Richer, Martin Indiana University School of Medicine Regulation of T cell differentiation by the transcription factor AFF3
Robinson, Christopher Indiana University School of Medicine The CD8 T cell response to Coxsackievirus B3
Schwantes-An, Tae-Hwi Indiana University School of Medicine Enhancing risk stratification for survival in PAH: Development of Polygenic Risk Scores
Tran, Ngoc Tung Indiana University School of Medicine CRISPR/Cas9-based correction of FANCC mutations for Fanconi Anemia group C gene therapy
Wang, Meijing Indiana University School of Medicine Sex-related differences in cardiac mitochondrial responses to inflammation following acute injury
Yoder, Rachel Indiana University School of Medicine Pilot Assessment of Integrated Mental Health Treatment for Children and Caregivers

2020 – Biomedical Research Grant (BRG)

Absalon, Sabrina Indiana University School of Medicine Functional investigation of key regulatory proteins in the completion of cell division in malaria parasites.
Biswas, Moanaro Indiana University School of Medicine Engineered TRuC Tregs to prevent germinal center responses to clotting factor VIII in hemophilia
Cornett, Evan Indiana University School of Medicine Regulation of the circadian clock by lysine methylation
DeSmet, Marsha Indiana University School of Medicine Mechanistic Role of Brd4 during Human Papillomavirus Replication
Takagi, Yuichiro Indiana University School of Medicine Structure and function of Mediator CDK8 module

2023 – Clinical & Translational Science (CTS)

Greenfield, Edward Indiana University School of Medicine Validation of a 3D Spheroid Platform to Personalize Oncology Drugs
Kolbinger, Fiona Purdue University Prediction and Early Detection of Pancreatic Cancer Using Multimodal Artificial Intelligence
Leung, Yuk Purdue University Improving Drug Discovery Efficiency for Retinal Degeneration by Functional Drug Screening
Lim, Kenneth Indiana University School of Medicine Creating a novel digital platform for capturing Cardiopulmonary Exercise Testing (CPET) data in Indiana

2022 – Collaboration in Translational Research (CTR)

Abebe, Ephrem Purdue University OTC Senior Station: A Consumer Facing Technology to Improve Medication Safety for Older Adults  
DePaoli-Roach, Anna Indiana University School of Medicine Identification of New Lead Small Molecules for the Treatment of Glycogen Storage Disease Type III; Cori Disease 
Holden, Richard Indiana University School of Medicine–Bloomington OTC Senior Station: A Consumer Facing Technology to Improve Medication Safety for Older Adults  
Honaker, Sarah Indiana University School of Medicine Sleep, feeding, and obesity risk during infancy in African American and Latinx families 
Jin, Xiaoming Indiana University School of Medicine Brain epigenetic mechanism of acupuncture on neuropathic pain 
Lee, Jessica Indiana University Indianapolis Addressing Disparities in Autism Spectrum Disorder (ASD) among Burmese Refugee families in Central Indiana 
Logrip, Marian / Lukkes, Jodi Indiana University Indianapolis / Indiana University School of Medicine Adolescent social isolation effects on alcohol drinking & neuroadaptations in dorsal raphe-basolateral amygdala circuit 
Lu, Tao Indiana University School of Medicine Improving the potency of novel PRMT5 inhibitor with nanocrystal technology to treat pancreatic cancer 
Moding, Kameron Purdue University Sleep, feeding, and obesity risk during infancy in African American and Latinx families 
Otte, Andrew Purdue University Long-acting ketamine for pain due to bone fracture 
Patel, Rita / Gupta, Kunal Indiana University–Bloomington / Indiana University School of Medicine Deep brain stimulation for laryngeal dystonia: from mechanism to optimal application  
Taylor, Rich University of Notre Dame Identification of New Lead Small Molecules for the Treatment of Glycogen Storage Disease Type III; Cori Disease 
White Fletcher Indiana University School of Medicine Long-acting ketamine for pain due to bone fracture 
Yuan, Chongli Purdue University Brain epigenetic mechanism of acupuncture on neuropathic pain 
Zhou, Xiang Purdue University Addressing Disparities in Autism Spectrum Disorder (ASD) among Burmese Refugee families in Central Indiana 

2021 – Collaboration in Translational Research (CTR)

Ferradal, Silvina Indiana University School of Medicine–Bloomington Early prediction of withdrawal in infants with prenatal opioid exposure using quantitative measurements
Goni Cortes, Joaquin Purdue University Uncovering fingerprints of brain network flexibility in alcohol use disorders 
Guo, Feng Indiana University School of Medicine–Bloomington A Tumor-on-a-Chip Platform for Modeling Immuno-Oncology in Prostate Cancer
Han, Bumsoo Purdue University Application of a biomimetic model to assess the effects of perfluoroalkyl substances (PFAS) on pancreatic cancer
Hocevar, Barbara / Kamendulis, Lisa Indiana University School of Medicine–Bloomington Application of a biomimetic model to assess the effects of perfluoroalkyl substances (PFAS) on pancreatic cancer 
Kareken, David Indiana University School of Medicine Uncovering fingerprints of brain network flexibility in alcohol use disorders 
Lu, Xin University of Notre Dame A Tumor-on-a-Chip Platform for Modeling Immuno-Oncology in Prostate Cancer 
O’Sullivan, Thomas D. University of Notre Dame Early prediction of withdrawal in infants with prenatal opioid exposure using quantitative diffuse optical spectroscopy
Raman, Subha / Stewart, Jesse Indiana University School of Medicine / Indiana University Indianapolis Longer-Term Cardiovascular and Psychiatric Consequences of SARS-CoV-2 Infection: Prevalence and Insights into Shared Mechanisms. 
Schlader, Zachary / Basile, David Indiana University–Bloomington / Indiana University School of Medicine Heat waves, aging, and the kidneys 

2023 – Community, Healthcare Delivery & Implementation Science PDT

Halverson, Colin Indiana University School of Medicine Emoji, Ethics, and Professionalism Focus Group Study
Mazurenko, Olena Indiana University Indianapolis Virtual perspective-taking training to reduce pain treatment disparities

2022 – Community, Healthcare Delivery & Implementation Science PDT

Johns, Shelley Indiana University School of Medicine Telephone Acceptance and Commitment Therapy Intervention for Caregivers (TACTICs) of Adults with Alzheimer’s Disease and Related Dementias: Pilot RCT
Vest, Joshua Indiana University Indianapolis Translating existing electronic data into computable social factor phenotypes
Vest, Joshua Indiana University Indianapolis IUCRC Phase 1: Center for Population Health Analytics & Technology (CPHAT)

2023 – Concepts to Clinic PDT

Brutkiewicz, Randy Indiana University School of Medicine MR1/MAIT cell axis in tau pathology
Plotkin, Lilian Indiana University School of Medicine Use of Novel Mice to Image Apoptotic Osteocytes
Powell, Nicholas Indiana University School of Medicine Discovery of mechanism-related biomarkers of CYP2C19 downregulation in NAFLD
Sheets, Patrick Indiana University School of Medicine Elucidating sex-specific disruption of mPFC circuits in chronic pain states
Yu, Andy Indiana University School of Medicine Function and mechanism of CD1d-mediated neuroinflammation after spinal cord injury

2022 – Concepts to Clinic PDT

Brutkiewicz, Randy Indiana University School of Medicine Modulating Neuroinflammation After Spinal Cord Injury
Callaghan, Tom Indiana University School of Medicine Addressing the Musculoskeletal Phenotype in Hypermobile Ehlers-Danlos Syndrome: Biomarker Pilot Study
Coggan, Andrew Indiana University Indianapolis Kynurenine and NAD+ as Biomarkers of ICU Acquired Weakness in Older Adults
Corson, Tim Indiana University School of Medicine Efficacy studies of SH-11037, a therapy for neovascular eye disease 
Gupta, Kunal Indiana University School of Medicine RNA sequencing of the whole dentate gyrus in early temporal lobe epileptogenesis
Hall, Mark Purdue University Cdc14 phosphatase roles in fungal drug resistance and pathogenesis
Hato, Takashi Indiana University School of Medicine Mechanisms of sepsis-induced organ failure
Jackman, Christopher Indiana University School of Medicine Bone effects of anti-CGRP medications for Migraine
Kacena, Melissa Indiana University School of Medicine In vivo SARS-CoV-2 exposure via dental aerosol in a COVID-19 mouse model
Khan, Babar Indiana University School of Medicine Improving sleep in acute respiratory failure ICU survivors
Lasagna-Reeves, Cristian Indiana University School of Medicine The role of Bassoon on pathological tau propagation in Alzheimer’s disease (AD) and other Tauopathies
Lockett, Angelia Indiana University School of Medicine S1P Induces Activation of the Mitochondrial Unfolded Protein Response to Promote Vascular Cell Proliferation in PAH
Maiers, Jessica Indiana University School of Medicine Elucidating the role of ATF6a as a critical pro-fibrogenic transcription factor in Hepatic Stellate Cells
Munoz Ramirez, Braulio Alfredo Indiana University School of Medicine Role of mu-opioid receptor activation on inhibitory transmission in dorsal striatum
Niziolek, Paul Indiana University School of Medicine MRI Determination of Femoral Neck Cortical Porosity in Chronic Kidney Disease Metabolic Bone Disease (CKD-MBD)
Plotkin, Lilian Indiana University School of Medicine Gonadal vs chromosomal sex and osteocytic miR21 in the control of bone mass and strength
Samala, Niharika Indiana University School of Medicine Sarcopenia in NASH Cirrhosis
Tesini Roseguini, Bruno Purdue University Home based leg heat therapy to combat age-related loss of skeletal muscle mass and function
Tran, Taun Indiana University School of Medicine Evaluating the dynamics and function of naturally acquired humoral immune responses to Plasmodium vivax vaccine candidate antigens in a longitudinal study

2020 – Concepts to Clinic PDT

Ballinger, Tarah Indiana University School of Medicine Impact of mechanical signals on bone and muscle composition in early stage breast cancer patients receiving aromatase inhibitors
Lu, Xin University of Notre Dame Generation of HA-tagged PYGO2 CRISPR knock-in mice at Jackson Laboratory

2023 – Core Pilot

Recipient
Institution
Title
Core(s)
Location(s)
Adams, Katrina University of Notre Dame Profiling neural stem and progenitor cells in Multiple Sclerosis Genomics and Bioinformatics Core Facility University of Notre Dame
Adeoye-Olatunde, Omolola Purdue University Evaluating the Impact of a Coach-Led Mobile Health (mHealth) Intervention on Hypertension Management in Nigeria Biostatistics and Health Data Science Core Indiana University School of Medicine
Androphy, Elliot Indiana University School of Medicine Proteomic Analysis of the alpha-COP interactome Center for Proteome Analysis Indiana University School of Medicine
Bidelman, Gavin Indiana University School of Medicine–Bloomington Characterizing the functional role of auditory corticofugal efferent pathways to human hearing using in-vivo multimodal neuroimaging Imaging Research Facility Indiana University–Bloomington
Brault, Jeffrey Indiana University School of Medicine Mitochondrial DNA mutations as a component of skeletal muscle atrophy Center for Medical Genomics Indiana University School of Medicine
Chan, Shing Fai Indiana University School of Medicine Serum Lipidomic Profiling and Lipid Metabolite Biomarker Discovery in Patients with Hemorrhagic Myocardial Infarction Metabolite Profiling Facility Purdue University
Custer, Sara Indiana University School of Medicine Axon-TRAP to survey local translation in mouse motor neurons Center for Medical Genomics Indiana University School of Medicine
Dahl, Richard Indiana University School of Medicine Determining the Contribution of Metabolic Disruption to the Anti-Inflammatory Phenotype of MIRC11-/- Macrophages Metabolite Profiling Facility Purdue University
Dydak, Ulrike Purdue University MRI Evaluation of Molecular Mechanisms of Perfusion and Renal Viability of Ex-Vivo Kidneys to Indicate Transplant Outcomes MRI Facility Purdue University
Gomes, Catia Indiana University School of Medicine Transcriptional profiling of human reactive astrocytes after complement pathway modulation Center for Medical Genomics Indiana University School of Medicine
Graham, Brett Indiana University School of Medicine Determination of the Altered Metabolome at Single Fiber Resolution in a Mouse Model of Mitochondrial Myopathy Metabolite Profiling Facility Purdue University
He, Qiuhong Purdue University Development of methods for simultaneous imaging of glioma markers MRI Facility Purdue University
Huot, Joshua Indiana University School of Medicine Transcriptional profiling of human reactive astrocytes after complement pathway modulation Genome Editing Center Indiana University School of Medicine
Lim, Kenneth Indiana University School of Medicine Development of A Novel a-Klotho Proteomic Assay Center for Proteome Analysis Indiana University School of Medicine
Lu, Tao Indiana University School of Medicine Critical role of novel NF-kB O-GlcNAcylation in pancreatic cancer Preclinical Modeling and Therapeutics Core Indiana University School of Medicine
Mukherjee, Angana University of Notre Dame Genomic Architecture of Unique Artemisinin Resistant Plasmodium falciparum from Bangladesh Genomics and Bioinformatics Core Facility University of Notre Dame
Noinaj, Nicholas Purdue University Structural characterization of novel inhibitors against Neisserial BAM Cryo-EM Facility Purdue University
O’Hagan, Heather Indiana University School of Medicine–Bloomington Elucidating the mechanism by which LSD1, CoREST2, and STAT3 promote enteroendocrine cell differentiation in mucinous colorectal cancer Center for Genomics and Bioinformatics Indiana University–Bloomington
Pelletier, Stephane Indiana University School of Medicine Lipid metabolism defects in SCYL1 deficiency syndrome Metabolite Profiling Facility Purdue University
Schutzman, Linda Indiana University School of Medicine Investigation of cellular adhesion molecules in pulmonary artery thrombosis following blunt thoracic trauma Indiana Center for Biological Microscopy Indiana University School of Medicine
Smith, Brenda Indiana University School of Medicine Profiling Candidate Xenometabolites Altered in Response to Prebiotic and Exercise for Improving Skeletal Health Metabolite Profiling Facility Purdue University
Smith, Gerald Indiana University School of Medicine–Bloomington Neurosteroid Metabolism and Evolution of Sexually Dimorphic Behavior Laboratory for Biological Mass Spectrometry Indiana University–Bloomington
Surowiec, Rachel Indiana University Indianapolis Improving Bone Stress Injury Prediction using Ultrashort Echo Time (UTE) Magnetic Resonance Imaging MRI Facility Purdue University
Tilston-Lunel, Natasha Louise Indiana University School of Medicine Identification of the cellular interacting partners of Oropouche virus non-structural protein NSs Center for Proteome Analysis Indiana University School of Medicine
Tran, Ngoc Tung Indiana University School of Medicine Targeting protein arginine methyltransferase 1 for multiple myeloma treatment In Vivo Therapeutics Core Indiana University School of Medicine
Witczak, Carol Indiana University School of Medicine Synthesis of a glucose photolabeling reagent for the identification of novel glucose transporters in skeletal muscle Chemical Genomics Core Facility Indiana University School of Medicine
Zhao, Bo Indiana University School of Medicine Generation of Knock-in Mice Expressing Fluorescently Tagged RIPOR2 Genome Editing Center Indiana University School of Medicine

2022 – Core Pilot

Recipient
Institution
Title
Core(s)
Location(s)
Conroy, Andrea Indiana University School of Medicine Lipid peroxidation as a modifiable target in severe malaria associated acute kidney injury  Proteomics Facility Metabolite Profiling Facility Purdue University
Das, Arupratan Indiana University School of Medicine Investigating glaucoma neuroprotection effect on the visual pathway of mice brain  In-Vivo Imaging Core Indiana University School of Medicine
Duffield, Giles University of Notre Dame The impact of Artificial light at night on Aedes aegypti biting behavior: a genomics analysis of the Zika mosquito brain   Genomics and Bioinformatics Core Facility University of Notre Dame
Ferdig, Michael University of Notre Dame Optimizing bulk segregant analysis of drug resistance in Plasmodium falciparum  Genomics and Bioinformatics Core Facility University of Notre Dame
He, Qiuhong Purdue University Fast Biomarker Imaging for Early Detection of Neoadjuvant Chemotherapy Response in Triple Negative Breast Cancer (TNBC) using pi-SelMQC Methods  In-Vivo Imaging Core Indiana University School of Medicine
Henderson, Gregory Purdue University Electron microscopy to assess cellular responses to altered fatty acid trafficking  Life Science Microscopy Facility Purdue University
Hetrick, William Indiana University School of Medicine–Bloomington Cerebellar Involvement in Social Cognition Processes in Schizophrenia  Imaging Research Facility Indiana University–Bloomington
Hockerman, Gregory Purdue University Characterization of beta cell-specific IRBIT knock out mice  Islet and Physiology Core Proteomics Facility Indiana University School of Medicine / Purdue University
Huot, Joshua Indiana University School of Medicine Tumor-derived FGF21 mediates musculoskeletal wasting in colorectal cancer  Genome Editing Center Indiana University School of Medicine
Little, Dianne Purdue University Histology of the Humeral Head and Glenoid in Asymptomatic Primary Glenohumeral Osteoarthritis Histology Research Laboratory Purdue University
Luo, Wei Indiana University School of Medicine The regulation of cross-reactivity in germinal center B cell response  Center for Medical Genomics Indiana Center for Biological Microscopy Indiana University School of Medicine
Ma, Yao-Ying Indiana University School of Medicine Highly Sensitive MRI to detect age and environmental effects in addiction models  In-Vivo Imaging Core Indiana University School of Medicine
Nelson, Rick Indiana University School of Medicine Multiomic Landscape of Human Vestibular Schwannomas  Center for Medical Genomics Indiana University School of Medicine
Patzke, Christopher University of Notre Dame Generation and Analysis of Translational Neural Cell Culture Models for Kabuki Syndrome: A Developmental Disorder Causing Intellectual Disability   Genomics and Bioinformatics Core Facility University of Notre Dame
Pierchala, Brian Indiana University School of Medicine Identification of the neuronal populations that underly the sense of taste  Center for Medical Genomics Indiana University School of Medicine
Tepper, Robert Indiana University School of Medicine Chronic Developmental Hypoxia Suppresses Airway Reactivity  Center for Medical Genomics Indiana University School of Medicine
Thompson, William Indiana University Indianapolis Generation of a Transgenic Mouse to Drive/Restore Perlecan Expression  Genome Editing Center Indiana University School of Medicine
Tillman, Emma Indiana University School of Medicine Cystic fibrosis transmembrane conductance regulator modulator plasma concentrations and correlation with mental and physical health adverse drug reactions  Clinical Pharmacology Analytical Core Indiana University School of Medicine
Vaughan, Kevin University of Notre Dame A Chemical Library Screen for Inhibitors of VRK1 Chemical Genomics Core Facility Purdue University
Weaver, Abigail University of Notre Dame A Deeper Dive into the Biofilm Architecture of Microbes Causing Prosthetic Joint Infection  Optical Microscopy Core University of Notre Dame
Yeh, Elizabeth Indiana University School of Medicine Phosphorylation-mediated Regulation of the Rubicon Interactome  Center for Proteome Analysis Indiana University School of Medicine

2021 – Core Pilot

Recipient
Institution
Title
Core(s)
Location(s)
Adeoye-Olatunde, Omolola Purdue University Social Determinants of Health and Medication Adherence among Chronically Ill Older Adults in the United States  Biostatistics and Health Data Science Core Indiana University School of Medicine
Atwood, Brady Indiana University School of Medicine Proteomic assessment of brain mechanisms underlying sex-specific effects of prenatal methadone exposure on alcohol-related behaviors   Center for Proteome Analysis Indiana University School of Medicine
Blazer-Yost, Bonnie Indiana University Indianapolis Characterization and Optimization of Target Compounds to Treat Hydrocephalus  Clinical Pharmacology Analytical Core Indiana University School of Medicine
Chang, Leifu Purdue University Mechanisms for inhibition of the Csy complex by anti-CRISPR proteins Cryo-EM Facility Purdue University
Cross, Tzu-Wen Purdue University Link between gut microbiome and brain proteome relevant to Parkinson’s Disease pathology   Proteomics Facility Purdue University
Datta, Meenal University of Notre Dame The myeloid “mechanome”: Identifying new treatment targets in glioblastoma Genomics and Bioinformatics Core Facility University of Notre Dame
De Luca, Thomas Indiana University School of Medicine Spatial metabolomics of sepsis-induced kidney injury in the diabetic milieu Metabolite Profiling Facility Purdue University
Ejendal, Karin Purdue University Analysis of the developing proteome in a mouse model of autism spectrum disorder  Proteomics Facility Purdue University
Engle, Staci Indiana University Indianapolis Role of hedgehog signaling in energy homeostasis and obesity Center for Proteome Analysis Indiana University School of Medicine
Gangopadhyay, Ishanti Indiana University School of Medicine–Bloomington Word learning mechanisms in bilingual children with Autism Spectrum Disorder: The use of social-pragmatic cues Biostatistics Consulting Center Indiana University–Bloomington
Greenfield, Edward Indiana University School of Medicine Regulation of Macrophage Subsets by Orthopaedic Wear Particles  Center for Medical Genomics Indiana University School of Medicine
Hall, Mark Purdue University Proteomic characterization of Cdc14 phosphatases in fungal pathogens  Proteomics Facility Purdue University
Howe, Erin University of Notre Dame Identification of the Rab11 interactome Proteomics Facility Purdue University
Huang, Jui-Yen Indiana University School of Medicine–Bloomington Elucidating molecular mechanisms underlying astrocytic FGFRs deficiency-induced neuroinflammation  Center for Medical Genomics Indiana University School of Medicine
Hundley, Heather Indiana University School of Medicine Identification of RNA editase-associated modulators of neurodegeneration in a Parkinson disease model  Flow Cytometry Core Facility Center for Genomics and Bioinformatics Indiana University–Bloomington
Kacena, Melissa Indiana University School of Medicine Skeletal Changes Following SARS-CoV-2 Infection Histology and Histomorphometry Core Indiana University School of Medicine
Kirchmaier, Ann Purdue University Metabolic Impacts on DNA Repair Center for Medical Genomics Bioinformatics Core Indiana University School of Medicine
Kitase, Yukiko Indiana University School of Medicine Osteocyte Energy Metabolism Under Mechanical Loading Histology and Histomorphometry Core Center for Medical Genomics Indiana University School of Medicine
Kono, Tatsuyoshi Indiana University School of Medicine Visualization of calcium dyshomeostasis in the pathogenesis of diabetes Indiana Center for Biological Microscopy Indiana University School of Medicine
Landreth, Gary Indiana University School of Medicine Therapeutic potential of the niacin receptor (HCAR2) in Alzheimer’s disease  Center for Medical Genomics Clinical Pharmacology Analytical Core Bioinformatics Core Indiana University School of Medicine
Lu, Tao Indiana University School of Medicine Characterization of the pharmacokinetic and metabolic properties of novel small molecule PRMT5 inhibitors Clinical Pharmacology Analytical Core Indiana University School of Medicine
Malek, Sarah Purdue University Fourier-transform infrared spectroscopy as a potential diagnostic and predictive biomarker of hip osteoarthritis  Biospecimen Management Core Indiana University School of Medicine
McDowell, Mary Ann University of Notre Dame Transcriptomics to Elucidate Methods of Lab-Induced Drug Resistance in Leishmania donovani Genomics and Bioinformatics Core Facility University of Notre Dame
Meyer, Jason Indiana University Indianapolis Proteomic analysis of reactive human astrocytes and derived soluble factors  Center for Proteome Analysis Indiana University School of Medicine
O’Hagan, Heather Indiana University School of Medicine–Bloomington Elucidating the role of DNA methylation and chromatin accessibility alterations in platinum-induced gene repression.  Center for Genomics and Bioinformatics Indiana University–Bloomington
O’Hagan, Heather Indiana University School of Medicine–Bloomington Elucidating the role of the AKT-EZH2-ß-catenin axis in mediating the transcriptional response to reactive oxygen species in colorectal cancer Center for Genomics and Bioinformatics Indiana University–Bloomington
Pattabiraman, Padmanabhan Indiana University School of Medicine Small Molecule screen to identify novel activators to lower intraocular pressure Chemical Genomics Core Facility Indiana University School of Medicine
Patton, John Indiana University Indianapolis Genetic Stability of Rotavirus Expression Platforms  Center for Genomics and Bioinformatics Indiana University–Bloomington
Sajdyk, Tammy Indiana University School of Medicine Evaluation of feasibility of a one-on-one personalized exercise intervention in adolescent and young adult cancer survivors  Regenstrief Data Services Regenstrief Institute
Schmidt, Nathan Indiana University School of Medicine Microbiome Impact in the Susceptibility of Red Blood Cell to Malaria Infection Flow Cytometry Resource Facility Indiana University School of Medicine
Schorey, Jeff University of Notre Dame Identifying to the species and subspecies level the non-tuberculosis mycobacteria present in sputum samples obtained from patients in Kenya, Africa Genomics and Bioinformatics Core Facility University of Notre Dame
Shannahan, Jonathan Purdue University Enhanced Resolution of Pulmonary Lipid Alterations via Mass Spectrometry Imaging Metabolite Profiling Facility Purdue University
Subramanian, Ramaswamy Purdue University Structure of Glycosomal Nucleotide Sugar Transporter – A Novel Target Against Disease-Causing Kinetoplastid parasites Cryo-EM Facility Purdue University
Tesini Roseguini, Bruno Purdue University Home-based leg heat therapy to combat age-related loss of skeletal muscle mass and function MRI Facility Purdue University
Wisner, Krista Indiana University School of Medicine–Bloomington A Biobehavioral Process Model of Persecutory Ideation in Early Psychosis  Imaging Research Facility Indiana University–Bloomington
Zhang, Li Indiana Biosciences Research Institute To measure islet antigens of type 1 diabetes using a highly multiplexed immunofluorescence assay  Indiana Center for Biological Microscopy Indiana University School of Medicine
Zhang, Siyuan University of Notre Dame Dissecting Breast Cancer and Therapy-induced Evolution of Myeloid Lineage by CITEseq  Genomics and Bioinformatics Core Facility University of Notre Dame

2020 – Core Pilot

Recipient
Institution
Title
Core(s)
Location(s)
Baker, Lane Indiana University School of Medicine–Bloomington Blood Brain Barrier Model Center for Genomics and Bioinformatics Indiana University–Bloomington
Bruzzaniti, Angela Indiana University Indianapolis Bone-cell specific actions of Kalirin  Histology and Histomorphometry Core Indiana University School of Medicine
Chan, Deva Purdue University Multi-Modal Magnetic Resonance Imaging for Functional Assessment of Tissue Repair  MRI Facility Purdue University
Clapp, David Indiana University School of Medicine FANCA-Dependent Mitotic Interactions Center for Proteome Analysis Indiana University School of Medicine
Daleke, David Indiana University School of Medicine–Bloomington Toward the cryo-EM structure of a P4-type ATPase monomer, Atp8a1  Electron Microscopy Center Indiana University–Bloomington
Das, Arupratan Indiana University School of Medicine Isolation and Characterization of Mitochondria to Investigate Mitochondrial Optic Neuropathy  Center for Proteome Analysis Flow Cytometry Resource Facility Center for Electron Microscopy Indiana University School of Medicine
Demas, Gregory Indiana University School of Medicine–Bloomington Steroidogenic Enzyme Regulation of Aggression  Laboratory for Biological Mass Spectrometry Indiana University–Bloomington
Dykhuizen, Emily Purdue University The Role of Polybromo1 (PBRM1) Loss in Checkpoint Inhibition Immunotherapy for Renal Cell Carcinoma  Biological Evaluation Purdue University
Elmendorf, Jeffrey Indiana University School of Medicine Imaging skeletal muscle insulin resistance in live mice Indiana Center for Biological Microscopy Indiana University School of Medicine
Fishel, Melissa Indiana University School of Medicine Pre-clinical pilot study to evaluate non-cytotoxic epigenetic therapy for pancreatic cancer  In Vivo Therapeutics Core Indiana University School of Medicine
Gao, Ming Indiana University School of Medicine–Northwest-Gary Analysis of RNA Helicase Me31B and Its Interacting RNAs by RNA sequencing  Center for Genomics and Bioinformatics Indiana University–Bloomington
Gavin, Tim Purdue University Aging and skeletal muscle exosome miRNA-seq  Center for Medical Genomics Bioinformatics Core Indiana University School of Medicine
Hoang, Quyen Indiana University School of Medicine High-throughput chemical screening against the Parkinson’s disease-associated protein LRRK2  Chemical Genomics Core Facility Indiana University School of Medicine
Kalinovsky, Anna Indiana University School of Medicine–Bloomington Effects of Phytocannabinoids on Cerebellar Axon Growth and Fasciculation  Light Microscopy Imaging Center Indiana University–Bloomington
Lu, Hui-Chen Indiana University School of Medicine–Bloomington Elucidate NMNAT2’s roles in brain health with longitudinal PET-MRI  In-Vivo Imaging Core Indiana University School of Medicine
Lu, Kun-Han Purdue University 4D MRI assessment of gastric motility after selective vagotomies in rats  MRI Facility Purdue University
Lu, Xin University of Notre Dame Go Keto: A New Paradigm to Enhance Cancer Immunotherapy  Freimann Life Sciences Center University of Notre Dame
Naidu, Samisubbu Indiana University School of Medicine Induction of Mitophagy in Endothelial Cells from Pulmonary Arterial Hypertension  Center for Electron Microscopy Indiana University School of Medicine
Newton, Irene Indiana University School of Medicine–Bloomington Understanding Bifidobacterium’s Presence in Infants Using Novel Sequencing  Center for Genomics and Bioinformatics Indiana University–Bloomington
Noinaj, Nicholas Purdue University Unraveling zinc piracy in Neisseria  Cryo-EM Facility Purdue University
Pestilli, Franco Indiana University School of Medicine–Bloomington Development and Validation of a Visual Field Mapping Protocol in Children Imaging Research Facility Indiana University–Bloomington
Snyder, Margie Purdue University Feasibility Pilot of Linking Patient-Reported Outcomes Collected in Community Pharmacies with Electronic Health Record Data  Regenstrief Data Services Regenstrief Institute
Takagi, Yuichiro Indiana University School of Medicine Structure of the Mediator complex of transcription regulation  Cryo-EM Facility Purdue University
Tang, Pei-Ciao Indiana University School of Medicine Regulation of Early Ectodermal Development Center for Medical Genomics Indiana University School of Medicine
Thompson, William Indiana University Indianapolis Generation of a Novel Mouse Model to Restore/Overexpress the a2d1 VSCC Subunit  Genome Editing Center Indiana University School of Medicine
Tisdale, James Purdue University Risk of Drug-Induced QT Interval Prolongation and Associated Proarrhythmia in Patients with Heart Failure with Preserved Ejection Fraction  Regenstrief Data Services Regenstrief Institute
Walczak, Claire Indiana University School of Medicine–Bloomington Single Cell Seq to Identify Heterogeneity in Polyploid Cells  Center for Genomics and Bioinformatics Indiana University–Bloomington
Warden, Stuart Indiana University Indianapolis Impact of physical activity on hip bone and cartilage health  In Vivo Therapeutics Core Indiana University School of Medicine
Yang, Danzhou Purdue University Structure Study of Nucleolin-MYC promoter DNA G-quadruplex Complex Cryo-EM Facility Purdue University
Ziarek, Joshua Indiana University School of Medicine–Bloomington Molecular mechanisms of arrestin activation  NMR Facility Indiana University–Bloomington

2022 – COVID-19 PDT

Agley, Jon Indiana University School of Medicine–Bloomington Pilot Study of a Brief Informational Intervention for COVID-19 Misinformation Prophylaxis
Connors, Jill Indiana University School of Medicine Addressing Mental Health Needs of Health Care Workers through Peer Support Groups During the COVID-19 Crisis
Gletsu-Miller, Nana Indiana University School of Medicine–Bloomington Associations between Nutritional Status of Vitamin D, Iron and Magnesium and Disease Severity of COVID-19
Kacena, Melissa Indiana University School of Medicine The role of megakaryocytes in regulating COVID-19 disease progression: A mouse model
Lim, Kenneth Indiana University School of Medicine Klotho-FGF23: Critical Biomarkers and Therapeutic Targets for Acute Kidney Injury (AKI) in COVID-19
Maupome, Gerardo Indiana University Indianapolis Hispanic COVID-19 Rapid Response Study: Characterization of Knowledge, Attitudes and Behaviors about COVID-19 Pandemic among Hispanic Respondents in Indiana
Minor, Kyle Indiana University Indianapolis How COVID-19 Impacts Daily Life: Comparing Serious Mental Illness and Healthy Adult Populations Pre-Post Social Distancing
Wang, Sophia Indiana University School of Medicine The Role of COVID-19 Endothelial Cell Dysfunction in Post-Intensive Care Unit (ICU) Depression and Anxiety Disorders

2020 – COVID-19 PDT

Baker, Brian University of Notre Dame Interrogating SARS-CoV-2 CTL antigens for immunobiology and potential T cell based vaccine strategies
Eckardt, Christopher Purdue University Ecological Momentary Assessment of Intimate Partner Violence During and After the COVID-19 Pandemic
Figueiredo, Marxa Purdue University Developing Targeted Therapeutics for Protecting and Treating COVID-19 Lung Disease

2023 – Grant Linking Universitywide Expertise (GLUE)

Hajos, Norbert / Wang, Nian Indiana University–Bloomington / Indiana University School of Medicine Brain-wide changes in connectome upon amygdala-driven epileptic seizures

2022 – Grant Linking Universitywide Expertise (GLUE)

Mitra, Anirban / Zhang, Chi Indiana University–Bloomington / Indiana University School of Medicine Regulation of ovarian cancer metastatic colonization through clonal selection  

2023 – Human Health & Biomedical Technology PDT

Byrn, Stephen / Clase, Kari Purdue University A platform for enhancing the potency of drugs
Chaudhry, Faria Purdue University Evaluating the impact of a community health worker for diabetes management in selfemployed women in India
Fernandes, Igor Purdue University Mapping the central and peripheral causes of autonomic dysfunction in pulmonary arterial hypertension
Koss, Wendy Purdue University Sex differences in the timing and severity of cognitive deficits and pathology using the 3xTg mouse model of Alzheimer’s disease
Metskas, Lauren / Kuhn, Richard Purdue University Fluorescent labeling of bunyavirus for in vivo assembly studies

2022 – Human Health & Biomedical Technology PDT

Bowman, Aaron / Rochet, Jean-Christophe Purdue University Sex Differences in Neuropathology and Excitotoxicity in a Stem Cell Model of Alzheimer’s Disease
Chaudhry, Faria Purdue University Evaluating the impact of a community health worker for diabetes management in selfemployed
Das, Chittaranjan Purdue University Identification of host targets of a bacterial effector with a novel deADP-ribosylase activity
Running, Cordelia / Gletsu Miller, Nana Purdue University Trading Sugar for Sparkle

2021 – Human Health & Biomedical Technology PDT

Bhunia, Arun Purdue University Fate of LAP as Excipient during Drug Delivery
Cooks, Robert Graham Purdue University Walk-up system to sample breath, perform MS and output Y/N respiratory infection status
DeMaria, Andrea Purdue University Improving Overall Quality of Life for Uterine Fibroid Patients
Hu, Chang-Deng Purdue University Cryo-EM Structural Analysis of PRMT5 in Complex with pINIn
Kimbrough, Adam Purdue University Exploring sex differences in how the brain responds to oxycodone use
Yang, Yang Purdue University The role of oxytocin in a mouse model of Scn2a deficiency

2020 – Human Health & Biomedical Technology PDT

Cross, Tzu-Wen Purdue University Gut microbiome and estrogen receptor signaling: potential implication on gastrointestinal-related disease
Foti, Daniel Purdue University Developing a novel protocol for home-based electroencephalography assessment of families affected by Angelman syndrome
Roseguini, Bruno Purdue University Heat therapy to improve skeletal muscle function in a model of Duchenne muscular dystrophy

2022 – Human Health & Biomedical Technology PDT / Women’s Global Health Institute

LaRoche, Kathryn Purdue University Exploring Patient Experiences with Miscarriage Care in Indiana in the Midst of a Shifting Regulatory Environment
Main, Russell / Figueriredo, Marxa Purdue University Maximizing peak bone mass: Interactions among genetics and mechanical loading

2023 – Large Collaborative Grant

Breathett, Khalid Indiana University School of Medicine Changing Generational Trajectory of CVD with the Adult Children and Grandchildren of WHI (TRAJECTORY Study)
Kacena, Melissa Indiana University School of Medicine Integrating clinical and preclinical data to identify novel therapeutics for chronic fracture pain
Lamb, Bruce Indiana University School of Medicine Genetic Alterations in Microglia and AD
Mosley, Amber Indiana University School of Medicine Thermal proteome profiling technologies to provide a mechanistic understanding of human genetic and epigenetic based diseases

2022 – Neuroscience / Cancer PRMC

Engleman, Eric Indiana University School of Medicine Modeling the interaction of alcohol and aging in Alzheimer’s disease
Lukkes, Jodi Indiana University School of Medicine Neural mechanisms underlying the effects of adolescent social isolation on stress-related serotonergic systems
O’Leary, Heather Indiana University School of Medicine Mechanisms and Targeting of Oxygen (O2) Mediated Calcium (Ca2+) Regulation in Malignant Hematopoietic Cells
Rietz, Anne Indiana University School of Medicine A pilot study to determine the spatial transcriptome in the spinal cord of SMA and control mice at postnatal day 4
Sharma, Tasneem Putliwala Indiana University School of Medicine Therapeutic intervention to target human glaucoma pathogenesis
Walker, Brian Indiana University School of Medicine Abnormal RNA processing in the pathogenesis and treatment of multiple myeloma

2022 – Obesity / Metabolism PRMC

DiMeglio, Linda / Hilliard, Marisa Indiana University School of Medicine Supporting HCL in early childhood (SHYNE): A randomized trial of a tailored educational and behavioral intervention for families of young children with type 1 diabetes
Dong, Charlie Indiana University School of Medicine PNPLA3 high-risk variant in alcoholic liver disease
Flak, Jonathan Indiana University School of Medicine Identifying the details of the VMH PACAP–>PAC1R system to reveal novel mechanisms required for energy expenditure control

2023 – Pediatric Fellowship

Adaikalam, Stephanie Indiana University School of Medicine Tracheomalacia in bronchopulmonary dysplasia: new insight on mechanism
Brown, Amber Indiana University School of Medicine Investigating the Feasibility and Safety of Osteopathic Medical Treatment in the Pediatric Oncology Inpatient Setting
Guerrro, Natalie Indiana University School of Medicine The Role Of Care-Oriented Behaviors In Adolescence As A Potential Moderating Factor In The Relationship Between Racial Discrimination And Mental Health
Huynh, Brittany Indiana University School of Medicine Adolescent and Caregiver Perspectives on Contraceptive Decision Making in the Setting of Teratogen Use and Rheumatic Disease

2022 – Pediatric Fellowship

Denizli, Merve Indiana University School of Medicine Novel Role of HSPC in Regulating Glucose Metabolism in Offspring of Obese Mice
Irwin, Caitlin Indiana University School of Medicine Optimizing Macronutrient Delivery in Human Breastmilk
Ray, Lauren Indiana University School of Medicine Incorporating mind-body skills with diabetes education in adolescents with type 1 diabetes

2020 – Pediatric Fellowship

Fairman, Korre Indiana University School of Medicine Disrupted cardiogenesis in Shroom 3 loss-of-function mice embryos in vivo
Malin, Stefan Indiana University School of Medicine Development of a Simulation-Based EMR Training Curriculum for Pediatric Resident
Severyn, Nicholas Indiana University School of Medicine Lung development under hypoxic conditions in a rat model 
Theisen, Alexandra Indiana University School of Medicine The Evaluation of Ovarian Reserve Using Anti-Mullerian Hormone in Young Women Diagnosed with Systemic Rheumatic Disease Compared to Controls

2023 – Pediatrics PDT

Kao, Shih-Chun Purdue University Supporting high-intensity interval training with mindfulness for enhancing childhood executive function
Sharp, Sacha Indiana University School of Medicine Improving Access to Quality Healthcare for Black Birthing People

2022 – Pediatrics PDT

Moding, Kameron Purdue University Objective remote assessments of family sleep and stress
Rodriguiz, Gabriela Indiana University School of Medicine Characterizing Usual Care for Youth with Disruptive Behavior Disorders in Indiana Community Mental Health Centers
Williams, Amy Indiana University School of Medicine Examination of mechanisms contributing to impact of insomnia on chronic pain risk and outcomes in pediatric patients

2021 – Pediatrics PDT

Aguilar, R. Claudio Purdue University Evaluating therapeutic strategies against Lowe syndrome

2020 – Pilot Funding

Clemmer, David Indiana University School of Medicine–Bloomington Developing Techniques for analysis of exosomes associated with wound healing

2023 – Postdoc Challenge

Recipient
Institution
Title
Core(s)
Location(s)
Dutta, Sayanta Indiana University School of Medicine Restoration of mitochondrial homeostasis for glaucoma neuroprotection Indiana University School of Medicine Center for Electron Microscopy Indiana University School of Medicine
Ekpruke, Carolyn Indiana University School of Medicine–Bloomington Assessing sex differences in the impact of a ketogenic diet on airway inflammatory cell response in allergen-challenged mice Flow Cytometry Core Facility Indiana University–Bloomington
Sohal, Ikjot Singh Purdue University Classification of human lung tumor specimens based on immune contexture Biospecimen Collection and Banking Core Histology Research Laboratory Indiana University School of Medicine / Purdue University
Souza, Rodolpho Ornitz Oliveira Indiana University School of Medicine Uncovering the role of Myosin A in Toxoplasma gondii mitochondrial biology by live imaging Indiana Center for Biological Microscopy Indiana University School of Medicine
Yu, Tao Indiana University School of Medicine Targeting Glutamine-Glutamate-Glutathione Axis Potentiates Immune Checkpoint Blockade Therapy in Colorectal Cancer Center for Medical Genomics Indiana University School of Medicine

2022 – Postdoc Challenge

Recipient
Institution
Title
Core(s)
Location(s)
Ahn, Taeyong Indiana University School of Medicine The use of nano‐liquid chromatography (LC‐MS) mass spectrometry for the identification of potential protein biomarker candidates related to an anterior cruciate ligament (ACL) injury Center for Proteome Analysis Indiana University School of Medicine
Ahn, Taeyong Indiana University School of Medicine The use of nano‐liquid chromatography (LC‐MS) mass spectrometry for the identification of potential protein biomarker candidates related to an anterior cruciate ligament (ACL) injury Center for Proteome Analysis Indiana University School of Medicine
Barboi, Cristina Indiana University Indianapolis Outcome analysis of intraoperative therapeutic interventions relative to the risk associated with progressive hypotension Regenstrief Data Services Regenstrief Institute
Barboi, Cristina Indiana University Indianapolis Outcome analysis of intraoperative therapeutic interventions relative to the risk associated with progressive hypotension Regenstrief Data Services Regenstrief Institute
Burke, Andrew Indiana University School of Medicine Contribution of social circuits to social familiarity-induced anxiolysis Behavioral Phenotyping Core Indiana University School of Medicine
Burke, Andrew Indiana University School of Medicine Contribution of social circuits to social familiarity-induced anxiolysis Behavioral Phenotyping Core Indiana University School of Medicine
Dou, Xiaozheng University of Notre Dame Structure-based drug design and investigation of cruentaren A analogs Magnetic Resonance Research Center Mass spectrometry and Proteomics Facility University of Notre Dame
Gampala, Silpa Indiana University School of Medicine Deciphering the effects of Ref‐1 redox inhibition on pancreatic cancer metabolism using non‐targeted global metabolomic profiling Metabolite Profiling Facility Purdue University
Gampala, Silpa Indiana University School of Medicine Deciphering the effects of Ref‐1 redox inhibition on pancreatic cancer metabolism using non‐targeted global metabolomic profiling Metabolite Profiling Facility Purdue University
Iyer, Shalini Purdue University Using mass spectrometry to characterize Ub‐related bacterial effectors from Legionella pneumophila Proteomics Facility Purdue University
Liffner, Benjamin Indiana University School of Medicine Proximal labelling of a kinase to identify proteins involved in mitosis of malaria parasites Center for Proteome Analysis Indiana University School of Medicine
Liffner, Benjamin Indiana University School of Medicine Proximal labelling of a kinase to identify proteins involved in mitosis of malaria parasites Center for Proteome Analysis Indiana University School of Medicine
Ma, Jing Indiana University School of Medicine Characterization of neutrophils-released EV-miRNA cargo in alcoholic hepatitis patients Center for Medical Genomics Indiana University School of Medicine
Ma, Jing Indiana University School of Medicine Characterization of neutrophils-released EV-miRNA cargo in alcoholic hepatitis patients Center for Medical Genomics Indiana University School of Medicine
Menon, Aishwarya Vijayan Purdue University Wound closure ability of a bio‐based tissue sealant Histology Research Laboratory Pre-Clinical Research Laboratory Purdue University

2021 – Postdoc Challenge

Recipient
Institution
Title
Core(s)
Location(s)
Chen, Xiaoling Purdue University Optogenetic method for synaptic weight mapping Bindley Bioscience Center Purdue University
Gomes, Catia Indiana University School of Medicine High-throughput screening to identify compounds able to block Glaucomatous Retinal Ganglion Cell degeneration Chemical Genomics Core Facility Indiana University School of Medicine
Huot, Joshua Indiana University School of Medicine Mediator of Musculoskeletal Deficits in Cancer Cachexia Genome Editing Center Indiana University School of Medicine
Reyes Fernandez, Perla Indiana University Indianapolis Regulation of Bone Mechanosensation via Proteoglycan-Based Matrix Tethers Histology and Histomorphometry Core Indiana University School of Medicine
Wright, Christian Indiana University Indianapolis Differential Expression Responses of Osteocytes to Mechanical Loading Following Knockout of the a2d1 Voltage Sensitive Calcium Channel Subunit Following Knockout of the α2δ1 Voltage Sensitive Calcium Channel Subunit Center for Medical Genomics Indiana University School of Medicine
Yen, Yu-Chen Purdue University Cryo-EM structure of adenylyl cyclase 5 in complex with Gβγ Cryo-EM Facility Purdue University
Zuilkoski, Caitlin Indiana University School of Medicine–Bloomington Elucidating the Role of Autophagy in Meiotic Progression Laboratory for Biological Mass Spectrometry Light Microscopy Imaging Center Indiana University–Bloomington

2023 – Research Enhancement Grant (REG)

Boone, David Indiana University School of Medicine Functional role for Thy1 (CD90) in colitis
Schwarz, Margaret Indiana University School of Medicine Epigenetic regulation of vascular remodeling in pulmonary hypertension

2022 – Research Enhancement Grant (REG)

Hollenhorst, Peter Indiana University School of Medicine–Bloomington Targeting cell type specific functions of the transcription factor ERG in prostate cancer 

2020 – Research Enhancement Grant (REG)

Schwarz, Margaret Indiana University School of Medicine Impact of Methionine Metabolism on lung disease of prematurity 

2023 – Sarah Roush

Martinez, Pablo Indiana University School of Medicine Therapeutic target of Bassoon for the treatment of tauopathies

2021 – Sarah Roush

Gomes, Catia Indiana University School of Medicine Inhibition of A1 astrocyte-induced neurodegeneration by targeting complement C3 

2023 – Showalter

Absalon, Sabrina Indiana University School of Medicine MCMCBP: a guardian of genome integrity during P. falciparum asexual replication
Barwinska, Daria Indiana University School of Medicine Assessment of the role of CD90+ proximal tubule cells in adaptive kidney repair in health and disease
Chen, Qiuyan Indiana University School of Medicine Structural Basis of Cancer Metastasis Mediated by Arrestin2 and STAM1 
Kuhn, Diane Indiana University School of Medicine Patient-Centeredness in Value-Based Emergency Care: A Mixed Methods Analysis of Patient Experience Data 
Metzger, Corinne Indiana University School of Medicine Exploring impacts of opioids and alternate therapies on bone in CKD 
Misra, Jagannath Indiana University School of Medicine Mechanisms of activation of eIF2 kinase GCN2 in response to UV exposer 
Needham, Brittany Indiana University School of Medicine Assessment of the role of CD90+ proximal tubule cells in adaptive kidney repair in health and disease
Pattabiraman, Padmanabhan Indiana University School of Medicine Novel Intraocular Pressure Lowering Strategy Targeting Lipid Biogenesis in Trabecular Meshwork 
Schutzman, Linda Indiana University School of Medicine Investigation of cellular adhesion molecules in pulmonary artery thrombosis following blunt thoracic trauma 
Templin, Andrew Indiana University School of Medicine Receptor interacting protein kinase signaling in ß-cell death and islet immune responses 
Tilston-Lunel, Natasha Louise Indiana University School of Medicine Comparative pathogenesis of OROV and OROV reassortants in a murine model 
Wang, Nian Indiana University School of Medicine A Novel Imaging Method for Diagnosis of Alzheimer’s Disease  

2022 – Showalter

Biswas, Moanaro Indiana University School of Medicine Targeting BAFF for modulation of adaptive immune responses to factor VIII replacement therapy 
Bogatcheva, Natalia Indiana University School of Medicine Small-molecule dual PARP1-PDL1 inhibitor as a mitigator of influenza-induced lung injury 
Canfield, Scott Indiana University School of Medicine–Terre Haute Blood-Brain Barrier Breakdown in Alzheimer’s Disease 
Cornett, Evan Indiana University School of Medicine Regulation of neuronal differentiation by lysine methylation
Das, Arupratan Indiana University School of Medicine Use of Human stem cell derived Retinal Ganglion Cells to investigate Nrf2 as therapeutic target for glaucomatous optic neuropathy 
Flak, Jonathan Indiana University School of Medicine Identifying novel CNS mechanisms that stimulate energy expenditure 
Janosevic, Danielle Indiana University School of Medicine The study of transcription and translational mediators of sepsis-associated kidney injury in the diabetic milieu. 
Lim, Kenneth Indiana University School of Medicine The Myocardial Cytoskeleton in Chronic Kidney Disease (CKD) 
Maiers, Jessica Indiana University School of Medicine ER-associated Degradation Drives Liver Fibrosis 
Naidu, Samisubbu Indiana University School of Medicine Non-canonical activation of SREBP1 in cardiovascular pathologies 
Schlecht, Stephen Indiana University School of Medicine Does the timing of ACL reconstructive surgery have an impact on long-term autograft outcomes? 
Shahbazi, Reza Indiana University School of Medicine Elucidating the role of exosomal communication in cancer bone metastasis for developing potent targeted therapeutics 
Sierra Potchanant, Elizabeth Indiana University School of Medicine Targeting PLK1 as a novel synthetic lethality strategy for acute myeloid leukemias with Fanconi anemia pathway mutations 
Snell, Laura Indiana University School of Medicine Elucidating Mechanisms of CD4 T Cell Cytotoxicity Following anti-PDL1 Immunotherapy 
Spaeth, Jason Indiana University School of Medicine Dynamic regulation of Pdx1 and islet ß-cell function by the Nucleosome Remodeling and Deacetylase complex 
Stewart, Lauren Indiana University School of Medicine Pilot study of home-based walking program after acute pulmonary embolism in patients with metabolic syndrome risk factors 
Tran, Ngoc Tung Indiana University School of Medicine Homology-Independent Targeted Integration mediated gene therapy for Fanconi Anemia group C 
Vilseck, Jonah Indiana University School of Medicine Accelerating Structure-Based Lead Optimization with AI-Inspired Molecular Generation and Fast Free Energy Calculations 
Yuan, Xue Indiana University School of Medicine Junctional epithelial stem cells as a therapeutic target for periodontal disease 
Zang, Yong Indiana University School of Medicine Transparent and efficient dose-finding clinical trial designs for targeted therapies and immunotherapy 
Zhang, Ji Indiana University School of Medicine Regulation of iron-dependent histone demethylation by amino acid starvation 
Zhang, Xinna Indiana University School of Medicine Identification of epigenetic inhibitors to sensitive triple negative breast cancer to immunotherapy 

2023 – Structural and Social Determinants of Health PDT

Shi, Yiyu University of Notre Dame Promoting Fairness in AI-Enabled Healthcare through Unsupervised Federated Learning: A Pilot Study

2022 – Structural and Social Determinants of Health PDT

Simon, Kosali / Gupta, Sumedha Indiana University–Bloomington / Indiana University Indianapolis Policy, economic and social determinants of health in Medicare populations

2023 – Trailblazer

Ballinger, Tarah / Hayes, Lisa Indiana University School of Medicine / 4-Ever-Pink Leveraging a community partnership to implement cascade risk assessment in Black families affected by breast cancer
Fodstad, Jill / Dwenger, Deanna Indiana University School of Medicine / Indiana Department of Corrections Taking a LEAP Forward: Assessing Initial Outcomes from a Training and Program Model for Improving Care in an Indiana Juvenile Correctional Setting for Incarcerated Hoosier Autistic Youth
Janota, Andrea / Parlett, Tyne Indiana University School of Medicine / Cultivating a Belonging Culture Expansion of a Student-Centric LGBTQIA+ Extension for Community Healthcare Outcomes (ECHO) Presentation Series
Jo, Soojung / Coddington, Jennifer Purdue University / Purdue’s North Central Nursing Clinics The Role of Social Media in COVID-19 and Influenza Vaccine Uptake in Rural Indiana
Lieberman, Marya / Cogdell, Joanne University of Notre Dame / Naxos Neighbors, LLC Implementing Community Drug Checking to Inform Personal and Community Harm Reduction Responses in a Regulation Restrictive Community
Miller, Michelle/Emery, Rachel Indiana University School of Medicine / LMH Women’s Health Center Trauma Informed Screening, Assessment, and Treatment for PTSD in Rural Pregnant Individuals
Wilburn, Victoria / Cochran, Nicki Indiana University Indianapolis / Overdose Lifeline, Inc Occupational Therapy as Part of an Interdisciplinary Model of Recovery Housing: A Feasibility Study

2022 – Trailblazer

Brandon-Friedman, Richard / Miller, Marissa Indiana University Indianapolis / Trans Solutions Research and Resource Center, LLC Pilot Testing the VISION Program to Enhance the Wellbeing of Transgender People of Color 
Cecil, Kara / Stinson, Kelsey University of Indianapolis / CICOA Aging and In-Home Solutions Hidden Families: Identification of and Assistance for Vulnerable Caregivers 
Franks, Melissa / Riggin, Katrina Purdue University / Indiana University Health Promoting Physical Activity Among Female Patients Following Cardiac Rehabilitation 
Hernandez, Elaine / Hicks, Ivan Indiana University–Bloomington / First Baptist Church North Indianapolis An Opportunity for Racial Equity in Health Care Access 
Macey, Erin / Rusnak, Colleen Indiana University Indianapolis / Indiana Health Fund Impact of Medical Debt Relief for Pregnant/Postpartum Women 
Peterson, Zoe / Shipley, Meagan Indiana University–Bloomington / Indiana University Health Healthy Relationships and Rural Youth: Evaluation of A Professional Development Training for Youth-Serving Adult Mentors 
Tucker-Edmonds, Brownsyne / Voisard, Andrea Indiana University School of Medicine / Goodwill of Central and Southern Indiana Nurse-Family Partnership Understanding birth team dynamics at Eskenazi Health and birth outcomes of Medicaid recipients who are MDwise members served by doulas  

2021 – Trailblazer

Galaviz, Karla / Stowers, Jill Indiana University–Bloomington / Indiana University Health Peer Recruitment in HIV Prevention
Gregory, Virgil / Muhammad, John Indiana University Indianapolis / Fathers and Families Center A Community Partner-University Collaboration for Increasing African American Men’s Access to Professional Mental Health Services: A Structural Equation
Jacob, Seethal / Meier, Emily Indiana University School of Medicine / Indiana Hemophilia and Thrombosis Center Sickle Cell Trait Education for Adolescents and Young Adults
Kong, Nan / Moore, Sheri Purdue University / National Alliance on Mental Illness West Central Indiana Examining the effect of community-based programs in coping with stress during COVID-19 recovery
Michael, Nancy / Gaudern, Carey University of Notre Dame / Beacon Health System – Community Impact Building Trauma-Informed Communities through NEAR Science and Change Theory
Renbarger, Kalyn / Hess, Cori Ball State University / Muncie Maternal Mental Health Coalition Mitigating the Effects of COVID-19 on Maternal Mental Health Through a Community-University Partnership
Rodriguez, Natalia / Kajumulo, Kelly Purdue University / Planned Parenthood Great Northwest, Hawaii, Alaska, Indiana, Kentucky Examining multilevel determinants of cervical cancer and acceptability of screening innovations to address disparities among Hispanic women in Lake County,Indiana
Wells, Ellen / Evans, T. Eric Purdue University / Blackford County Concerned Citizens Rural Environmental Health Assessment and Neighborhood-Specific Public Health Plan for Hartford City Using a Community-Engaged Approach

2020 – Trailblazer

Abebe, Ephrem / Wheeler, Holly Purdue University / Family Voices Indiana Medication Access and Safety for Children with Special Healthcare Needs (CSHCNs) During the COVID-19 Pandemic 
Hannon, Tamara / Gough, Tyler Indiana University School of Medicine / Indy Urban Acres Expanding Veggie Box Access to Neighbors (EVAN) 
Howland, Allison / Norris, Katherine Indiana University / Homes 4 Homeless Hotels to Home: A study of ethical, low-barrier approaches to episodic homelessness in Monroe County, Indiana 
Rodriguez, Natalia / Layton, Jennifer Purdue University / LTHC Homeless Services Mitigating COVID-19 Impacts on the Homeless Population of Tippecanoe County: A CHW-Led Approach 
Simpson, Vicki / Archibald, Lorra Purdue University / Healthy Communities of Clinton County Using Social Network Analysis to Create an Effective Health Coalition to Support A Systems Level Approach to Improve Health Outcomes and Reduce Disparities 
Spence, Lisa / Parker, Robin Indiana University–Bloomington / Indiana University Health Effect of Adding a Registered Dietitian in a Team Based Approach for Management of Type 2 Diabetes
Yeager, Valerie / Berman, Kathy Indiana University Indianapolis / About Special Kids Supporting Families and Children with Complex Health and Social Needs: Evaluating About Special Kids’ Participation in Care Conferences

2019 – Trailblazer

Amireault, Steve / Lowry, Kristen Purdue University / Purdue Extension Factors Associated with the Maintenance of Physical Activity Beyond Program Termination: A Longitudinal Investigation Among Rural Older Adults 
Greene, Alison / Sherwood Laughlin, Catherine / Bruner, Kathy / Greathouse, Lisa Indiana University–Bloomington / Monroe County Community School Corporation / Indiana University Health Sexual Health Equity for School-Aged Youth with Special Needs 
Lefever, Jennifer / Botchway, Marian / Zeltwanger, Todd University of Notre Dame / Cultivate Food Rescue Food for Families: The impact of a backpack program on lessening child hunger, improving school attendance, behavior and academic outcomes 
Nault Connors, Jill / Hayden, Julie Indiana University Indianapolis / National Alliance on Mental Illness (NAMI) of Greater Indianapolis Building Grass Roots Advocacy through Photovoice for Improved Policy and Practice Targeting Health & Healthcare Needs Among Individuals with Mental Illness 
Weathers, Tess / Girls, Nikki Indiana University Indianapolis / Concord Neighborhood Center Exploring the life expectancy gap in the Near-Southside as a bridge to action for a healthier community 
Wilburn, Victoria / Wonnell, Robin Indiana University Indianapolis / Overdose Lifeline, Inc Life Skills: The Power of Doing 

2023 – Trailblazer Planning

Bucher, Sherri / Cochran, Nicki Indiana University Indianapolis / Overdose Lifeline, Inc The Central Indiana C4HOPE Coalition to support substance use disorder recovery among pregnant and mothering women and their children
Erniosho, Temitope / McKamey, Jessica Indiana University–Bloomington / Bloomfield Eastern-Greene County Public Library A Community-Academic Partnership to Promote Nutrition Using a Community Garden
Greene, Alison / Cox, Missy Indiana University–Bloomington / Jackson County Drug Court Building a Community-Academic Partnership to Improve Drug Court Process & Practice: Jackson County Drug Court and IU School of Public Health-Bloomington
Gregory, Virgil / Vaughn, Darlene Indiana University Indianapolis / ROCFK Examining Childhood Trauma Readiness among Youth Workers
Higley, Keeley / Kasting, Monica / Vivo, Sarah Indiana University School of Medicine / Purdue University / Indiana Immunization Coalition Purdue University- Indiana Immunization Coalition Partnership to Enhance the Health Emerging Adult Leaders Program

2022 – Trailblazer Planning

Fodstad, Jill / Dwenger, Deanna Indiana University School of Medicine / Indiana Dept of Corrections Improving Care for Incarcerated Hoosier Youth with Autism Spectrum Disorder through Developing an Indiana Department of Corrections Staff Training
Klitzman, Melissa / Davis, Tiffany Indiana University School of Medicine / Marion County Public Health Department Community-University Partnership Establishing a Black Peer-Led Lactation Support Group for NICU Families
Kostrominova, Tatiana / Walker, Roland Indiana University Northwest / Gary Health Department Building partnership for reducing health disparities in the City of Gary through research and education
Miller, Michelle/Emery, Rachel Indiana University School of Medicine / LMH Women’s Health Center Building Partnerships for Trauma-Informed Care in Rural Perinatal Populations
Weber, Zachary / Parlett, Tyne Indiana University Indianapolis / Cultivating a Belonging Culture Development of a Student-Centric LGBTQIA+ Extension for Community Healthcare Outcomes (ECHO) Presentation Series

2021 – Trailblazer Planning

Brandon-Friedman, Richard / Miller, Marissa Indiana University Indianapolis / Trans Solutions Research and Resource Center, LLC Building Community Partnerships to Enhance the Safety and Well-being of Transgender People of Color 
Frederickson Comer, Karen / Robertson, Richard Indiana University Indianapolis Strategic Needs Assessment for Physicians’ Initiative for Demographic Analysis
Jones, Carmen / Cripe, Nancy Sue Purdue University / Carroll-White Counties CASA Child Welfare Training for Court Appointed Special Advocate (CASA) Volunteers
Magan, Amy / Stinson, Kelsey University of Indianapolis / Center for Aging & Community UIndy-CICOA Partnership for Innovations in Healthy Aging
Michael, Nancy / White, Cassy University of Notre Dame / St. Joseph County Department of Health Developing Collaborative Public Health Approaches for Positive and Adverse Childhood Experiences 
Trainor, Kristin / Hudson, Ken Indiana University Indianapolis / Whitely Community Council Whitely Community Council and Ball State University: Partnership for Improved Health Outcomes 
Tucker-Edmonds, Brownsyne / Maxey, Rachel / Voisard, Andrea Indiana University School of Medicine / MDWise and GoodwillIndy Working Group of University and community partners to learn about Indiana maternal mortality and morbidity rates and examine the potential patient value-add of the Eskenazi Doula Pilot 

2020 – Trailblazer Planning

Enane, Leslie Anne / Koch, Sarah Indiana University School of Medicine / Marion County Health Department Building Partnerships in Tuberculosis and Refugee Health Care in Indiana
Renbarger, Kalyn / Hess, Cori Ball State University / Muncie and Delaware County Maternal Mental Health Coalition A Community-University Partnership Aimed to Improve Maternal Mental Health in Delaware County
Rodriquez, Natalia / Gonzalvo, Jasmine / Meredith, Ashley / Ruiz, Yumary / Hart, Margarita Purdue University / Indiana Community Health Worker Association Indiana Community Health Workforce Development Institute
Simpson, Vicki / Archibald, Lorra Purdue University / Healthy Communities of Clinton County Enhancing an Academic-Community Partnership to Improve Outcomes

2019 – Trailblazer Planning

Abebe, Ephrem / Akers, Jennifer Purdue University / Family Voices Indiana Community-Academic Partnership for Improved Medication Use Outcomes 
Cherian, Joseph / Shaw, Gillian University of Notre Dame / enFocus Building a partnership between the University of Notre Dame, the St. Joseph County Health Department, and enFocus to work towards a lead-safe county 
Knapp, Doug / Street, Tim Indiana University–Bloomington / Bradford Woods The Development of Camp Chrysalis – A transformational program for the management of obesity and pre-diabetic conditions in adolescents.  
Kong, Nan / Moore, Sheri Purdue University / National Alliance on Mental Illness West Central Indiana Smartphone-based Socio-behavioral Monitoring Tool Development for Early Detection and Prevention of Major Depression 
P’Pool, April / Berman, Kathy Indiana University Indianapolis / About Special Kids Teaching Medical Students About Social Determinants of Health Through Partnership with About Special Kids and Care Conferences 
Wadelton, Christina / Mouhiuddin, Salma / Beaty, Victoria Indiana University Indianapolis / Growing Places Indy / IU Health Addressing Food Insecurity in Children with Special Needs through Urban Gardening 

2023 – Translational Population Health (TPH)

Capone, Drew Indiana University School of Medicine–Bloomington Baseline evaluation of a city-wide sanitation intervention in Quelimane, Mozambique
Del Rio, Michelle Indiana University School of Medicine–Bloomington A community-engaged intervention for reducing lead exposure in a high-risk population
Pickett. Andrew Indiana University School of Medicine–Bloomington Characterizing Social Network Support for Physical Activity among Sexual and Gender Minority (SGM) Caregivers of People Living with Alzheimer’s Disease (AD) and Related Dementias (AD/ADRD)

2022 – Translational Population Health (TPH)

Jordan, Evan / Johns, Shelley Indiana University–Bloomington / Indiana University School of Medicine A just in time mobile stress intervention for cancer survivors

IP Filings Based on CTSI Projects

We would like to thank the Innovation and Commercialization Office at Indiana University, the Office of Technology Commercialization at Purdue University, and the Idea Center at the University of Notre Dame for their assistance in publishing this webpage. Each of these offices helps to identify, protect and commercialize technology that comes from discoveries and innovations made by their researchers. Examples of previously awarded projects that have resulted in IP or commercialization include:

2008 - Awards Resulting in IP Protection and Commercialization Activities

Won, You-Yeon Purdue Radiation-Controlled Release of Drugs for Chemo-Radiotherapy

2010 - Awards Resulting in IP Protection and Commercialization Activities

Cooks, Robert Graham Purdue Morphologically Friendly Tissue Imaging

2012 - Awards Resulting in IP Protection and Commercialization Activities

Boudouris, Bryan Purdue Functional Filtration Membranes
Rickus, Jenna Purdue Multianalyte Sensing

2015 - Awards Resulting in IP Protection and Commercialization Activities

Figueiredo, Marxa L Purdue Anti-Angiogenesis Compound Targets Laminin Receptor in Cancer Cells
Thompson, David Purdue Method Produces Cyclodextrin with Polyrotaxane has Potential as Part of Treatment of Neimann-Pick Disease Type C
Won, You-Yeon Purdue Using Nanoparticles for Cancer Therapy

2016 - Awards Resulting in IP Protection and Commercialization Activities

Shi, Riyi Purdue Portable Diagnostic Tool for Blast Injury and Other Traumatic Brain Injuries

2017 - Awards Resulting in IP Protection and Commercialization Activities

Chen, Peng-Shen Indiana University Use of Subcutaneous Nerve Stimulation to Sprout Nerves
Corson, Timothy Indiana University Novel Method of Using Soluble Epoxide Hydrolase Inhibitors
Emir, Uzay E Purdue Noninvasive Ultra-short Acquisition Delay Magnetic Resonance Spectroscopy Measurement
Lu, Tao Indiana University PRMT5 Inhibitors for the Treatment of Cancer

2018 - Awards Resulting in IP Protection and Commercialization Activities

Merrell, Jonathan Indiana University Revised Smart Inhaler
Mirmira, Raghu Indiana University Method for predicting susceptibility to hyperglycemia and type 1 diabetes

2020 - Awards Resulting in IP Protection and Commercialization Activities

Ekser, Burcin Indiana University In Vitro Model for the Study of Liver Disease
Androphy, Elliot Indiana University Small Molecule Covalent Inhibitors of the HPV E6 Protein
van Kessel, Julia Indiana University Novel Antibiotics

For additional, campus-specific information about project innovation and entrepreneurship please contact them using the information below.

Office of Technology Commercialization (OTC) The Convergence Center 101 Foundry Drive, Suite 2500 West Lafayette, IN 47906 Phone: 765-588-3475 Email: OTCIP@prf.org www.prf.org/innovation-and-entrepreneurship www.prf.org/otc

University of Notre Dame Licensing & Business Development The Idea Center 574-631-8825 cjennin5@nd.edu https://ideacenter.nd.edu

Indiana University Innovation and Commercialization Office 518 Indiana Avenue Indianapolis, IN 46202 317-274-5905 ico@iu.edu https://research.iu.edu/innovation-commercialization

Get Involved with Indiana CTSI