This case series reports the characteristics, clinical presentation, and outcomes of patients hospitalized with coronavirus disease 2019 (COVID-19) in the New York City area between March 1, 2020, and April 4, 2020.

The authors examined data from 5700 patients with COVID-19 admitted to 12 hospitals in New York City, Long Island, and Westchester County, New York, within the Northwell Health system. Among these  patients, the most common comorbidities were hypertension (56.6%), obesity (41.7%), and diabetes (33.8%). Among patients who were discharged or died (n = 2634), 14.2% were treated in the intensive care unit, 12.2% received invasive mechanical ventilation, 3.2% were treated with kidney replacement therapy, and 21% died.

Other characteristics included:

• Median age was 63 years [interquartile range {IQR}, 52-75; range, 0-107 years]
• 39.7% were female
• At triage, 30.7% of patients were febrile, 17.3% had a respiratory rate greater than 24 breaths/minute, and 27.8% received supplemental oxygen.
• The rate of respiratory virus co-infection was 2.1%.
• A total of 45 patients (2.2%) were readmitted during the study period. The median time to readmission was 3 days (IQR, 1.0-4.5) for readmitted patients.
• Among the 3066 patients who remained hospitalized at the final study follow-up date (median age, 65 years [IQR, 54-75]), the median follow-up at time of censoring was 4.5 days (IQR, 2.4-8.1).

Outcomes were assessed for 2634 patients who were discharged or had died at the study end point. Among these patients:

• During hospitalization, 373 patients (14.2%) (median age, 68 years [IQR, 56-78]; 33.5% female) were treated in the intensive care unit care, 320 (12.2%) received invasive mechanical ventilation, 81 (3.2%) were treated with kidney replacement therapy, and 553 (21%) died.
• Mortality for those requiring mechanical ventilation was 88.1%.
• The median postdischarge follow-up time was 4.4 days (IQR, 2.2-9.3)