This retrospective study show age-dependent expression of ACE2 in nasal epithelium, the first point of contact for SARS-CoV-2 and the human body. This may shed light on why children only appear to account for a small proportion of COVID-19 cases. Angiotensin-converting
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Below is a roundup of some recent developments with law and ethics themes related to the enforcement of public health authority during the pandemic, vulnerable populations, and states reopening. The Americans with Disabilities Act & HIPAA do not bar businesses
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This article reviews the outcome of surgical procedures for asymptomatic undiagnosed COVID-19 patients. Article searches focused on all patients who were preoperatively asymptomatic and not tested for COVID-19 and were conducted on April 4, 2020. The authors identified 4 reports
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This retrospective study assessed the characteristics and early outcomes of 200 patients hospitalized with COVID-19 in the Bronx, focusing on obesity as a risk factor for poor outcomes. Using multivariate analysis, the authors found that severe obesity (BMI≥35), male sex,
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This small study estimated the prevalence of SARS-COV-2 among pediatric cancer patients at Memorial Sloan Kettering Cancer Center in the US. Between March 10 and April 12, 2020, the center performed a total of 335 tests for SARS-CoV-2 among 178
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This summary from the Centers for Disease Control and Prevention (CDC) provides background information on the recently described cases of multisystem inflammatory syndrome in children (MIS-C) associated with coronavirus disease 2019 (COVID-19); and 2) a case definition for this syndrome.
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This study found up-to-date vaccination coverage from children 24 months of age and younger declined in all age cohorts except the birth-dose hepatitis B coverage. Among children aged 5 months, up-to-date status for all recommended vaccines declined from approximately two
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This systematic review and meta-analysis analyzes the COVID-19 disease characterization in pediatric age groups, including the possibility of vertical transmission to neonates. The authors examined articles published up to April 2, 2020. Among these studies, the most frequently reported symptoms
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This systematic review and meta-analysis shows that diabetes mellitus (DM) is associated with mortality, severe COVID-19, acute respiratory distress syndrome (ARDS), and disease progression in patients with COVID-19. The authors examined 6452 patients from 30 studies assessing DM, COVID-19, and
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This study presents new evidence on the potential rise in maternal and child mortality in low-income and middle-income countries if essential health services are disrupted as a result of COVID-19. The authors modeled three hypothetical scenarios in which the coverage
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